Effect of mode of administration on guaifenesin pharmacokinetics and expectorant action in the rat model

Pulmonary Pharmacology and Therapeutics

Volumn 22, Issue 3, 2009, Pages 260-265

  Kagan, Leonid ^a   Lavy, Eran ^b   Hoffman, Amnon ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Expectorant; Gastric stimulation; Local action; Pharmacokinetics pharmacodynamics; Region specific absorption; Respiratory secretion; Vagal reflex

Indexed keywords

GUAIFENESIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BRONCHUS SECRETION; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG MECHANISM; GASTROINTESTINAL TRACT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH ABSORPTION; SYSTEMIC CIRCULATION;

ALGORITHMS; ANIMALS; COLORING AGENTS; COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPECTORANTS; GUAIFENESIN; INJECTIONS, INTRAVENOUS; INTUBATION, GASTROINTESTINAL; MALE; MODELS, STATISTICAL; PHENOLSULFONPHTHALEIN; RATS; RATS, WISTAR; RESPIRATORY SYSTEM;

EID: 67349254121     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2008.12.020     Document Type: Article

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