The relation of testosterone levels with fatigue and apathy in Parkinson's disease

Clinical Neurology and Neurosurgery

Volumn 111, Issue 5, 2009, Pages 412-414

  Kenangil, Gülay ^a   Orken, Dilek Necioglu ^a   Ur, Emel ^a   Forta, Hulki ^a   Celik, Munevver ^a  

^a SISLI ETFAL TRAINING AND RESEARCH HOSPITAL   (Turkey)

Author keywords

Apathy; Disease severity; Fatigue; Parkinson's disease; Testosterone

Indexed keywords

TESTOSTERONE;

ADULT; APATHY; APATHY EVALUATION SCALE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; FATIGUE; FATIGUE SEVERITY SCALE; HUMAN; MALE; PARKINSON DISEASE; PATHOPHYSIOLOGY; RATING SCALE; TESTOSTERONE BLOOD LEVEL; UNIFIED PARKINSON DISEASE RATING SCALE;

ACTIVITIES OF DAILY LIVING; AGED; AGED, 80 AND OVER; ANTIPARKINSON AGENTS; FATIGUE; HUMANS; LEVODOPA; MALE; MIDDLE AGED; PARKINSON DISEASE; SEVERITY OF ILLNESS INDEX; TESTOSTERONE;

EID: 67349248431     PISSN: 03038467     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clineuro.2008.11.019     Document Type: Article

References (33)

1. Okun M.S., McDonald W.M., and Delong M.R. Refractory nonmotor symptoms in male patients with Parkinson disease due to testosterone deficiency. Arch Neurol 59 (2002) 807-811
2. Okun M.S., Walter B.L., McDonald W.M., Tenover J.L., Green J., Junkos J.L., et al. Beneficial effects of testosterone replacement for the nonmotor symptoms of Parkinson disease. Arch Neurol 59 (2002) 1750-1753
3. Shulman L.M., Taback R., Rabinstein A.A., and Weiner W.J. Non-recognition of depression and other non-motor symptoms in Parkinson's disease. Parkinsonism Relat Disord 8 (2002) 193-197
4. Chaudhuri K.R., Healy D.G., and Schapira A.H.V. Nonmotor symptoms of Parkinson's disease: diagnosis and management. Lancet Neurol 5 (2006) 235-245
5. Schrag A. Psychiatric aspects of Parkinson's disease. J Neurol 251 (2004) 795-804
6. Tenover J.S., Matsumoto A., Clifton D.K., and Bremner W.J. Age related alterations in the circadian rythms of pulsatile luteinizing hormone and testosteron secretion in healthy men. J Gerontol 43 (1988) 163-169
7. Harman S.M., Metter E.J., Tobin J.D., Pearson J., and Blackman M.R. Baltimore Longitudinal Study of Aging. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. J Clin Endocrinol Metab 86 (2001) 724-731
8. Seidman S.N., and Rabkin J.G. Testosteron replacement therapy for hypogonadal men with SSRI-refractory depression. J Affect Disord 48 (1998) 57-61
9. Okun M.S., Crucian G.P., Fischer L., Walter B.L., Testa C.M., Vitek J.L., et al. Testosterone deficiency in a Parkinson's disease clinic: results of a survey. J Neurol Neurosurg Psychiatry 75 (2004) 165-166
10. Ready R.E., Friedman J., Grace J., and Fernandez H. Testosterone deficiency and apathy in Parkinson's disease: a pilot study. J Neurol Neurosurg Psychiatry 75 (2004) 1323-1326
11. Hughes A.J., Ben-Shlomo Y., Daniel S.E., and Lees A.J. What features improve the accuracy of clinical diagnosis in Parkinson's disease: a clinicopathologic study. Neurology 42 (1992) 1142-1146
12. Fahn S., Elton R.S., and Members of the UPDRS Development Committee. Unified Parkinson's Disease Rating Scale. In: Fahn S., Marsden C.D., Calne D.B., and Goldstein M. (Eds). Recent developments in Parkinson's disease (1987), Macmillan Publishers, Florham Park, NJ 153-163
13. Karlsen K.H., Larsen J.P., Tandberg E., and Jorgensen K. Fatigue in patients with Parkinson's disease. Mov Disord 14 (1999) 237-241
14. Pluck G.C., and Brown R.G. Apathy in Parkinson's disease. J Neurol Neurosurg Psychiatry 73 (2002) 636-642
15. Folstein M.F., Folstein S.E., and McHugh P.R. Mini Mental State. A practical method for grading the cognitive state of patients for clinician. J Psychiatr Res 12 (1975) 189-198
16. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. (1994), APA, Washington, DC
17. Beck A.T., Ward C., and Mendelson M. Beck depression inventory (BDI). Arch Ger Psychiatry 4 (1961) 561-571
18. Hisli N. Beck depresyon envanterinin üniversite öǧrencileri için geçerliliǧi, güvenilirliǧi. Psikoloji 7 (1989) 3-13
19. Krupp L.B., La Rocce N.G., Muir-Nash J., and Steinberg A.D. The fatigue severity scale; application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol 46 (1989) 1121-1123
20. Herlefson K., and Larsen J.P. Measuring fatigue in patients with Parkinson's disease-The Fatigue Severity Scale. Eur J Neurol 9 (2002) 595-600
21. Marin R.S., Biedrzycki R.C., and Firinciogullari{dotless} S. Reliability and validity of the apathy evaluation scale. Psychiatr Res 38 (1991) 143-162
22. Gülseren S., Atun C., Erol A., Aydemir O., Çelebisoy M., and Kültür S. Apati deǧerlendirme ölçeǧi Türkçe formunun geçerlilik ve güvenilirlik çali{dotless}şmasi{dotless}. Nöropsikiyatri Arşivi 38 (2001) 142-150
23. Grosset K., Needleman F., Macphee G., and Grosset D. Switching from ergot to nonergot dopamine agonists in Parkinson's disease: a clinical series and five-drug dose conversion table. Mov Disord 19 (2004) 1370-1374
24. Goetz C.G., Blasucci L., and Stebbins G.T. Switching dopamine agonists in advanced Parkinson's disease. Is rapid titration preferable to slow?. Neurology 52 (1999) 1227-1229
25. Karachi C., Yelnki J., Tande D., Tremblay L., Hirsch E.C., and Francois C. The pallidosubthalamic projection: an anatomical substrat for nonmotor functions of the subthalamic nucleus in primates. Mov Disord 20 (2005) 172-180
26. Friedman J., and Friedman H. Fatigue in Parkinson's disease. Neurology 43 (1993) 2016-2018
27. Krupp L.B., and Polline D.A. Mechanisms and management of fatigue in progressive neurological disorders. Cur Opin Neurol 9 (1996) 456-460
28. Abe K., Takanashi M., and Yanagihara T. Fatigue in patients with Parkinson's disease. Behav Neurol 12 (2000) 103-106
29. Friedman J.H., Brown R.G., Comella C., Garber C.E., Krupp L.B., Lou J.S., et al. Fatigue in Parkinson's disease: a review. Mov Disord 22 (2007) 297-308
30. Friedman J.H., and Friedman H. Fatigue in Parkinson's disease: a nine year follow-up. Mov Disord 16 (2001) 1120-1122
31. Isella V., Melzi P., Grimaldi M., Iurlaro S., Piolti R., Ferrarese C., et al. Clinical, neuropsychological and morphometric correlates of apathy in Parkinson's disease. Mov Disord 17 (2002) 366-371
32. Azad N., Pitale S., Barnes W.E., and Friedman N. Testosterone treatment enhances regional brain perfusion in hypogonadal men. J Clin Endocrinol Metab 88 (2003) 3064-3068
33. Okun M.S., Fernandez H.H., Rodriguez R.L., Romrell J., Suelter M., Munson S., et al. Testosterone therapy in men with Parkinson disease. Results of the TEST-PD Study. Arch Neurol 63 (2006) 729-735