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Volumn 7, Issue 5, 2009, Pages 502-508

Treatment of Chronic Constipation: Current Pharmacologic Approaches and Future Directions

Author keywords

[No Author keywords available]

Indexed keywords

17 METHYLNALTREXONE; AT 1705; BISACODYL; CISAPRIDE; DOCUSATE CALCIUM; DOCUSATE SODIUM; GUANYLATE CYCLASE ACTIVATOR; ISPAGULA; LACTULOSE; LAXATIVE; LINACLOTIDE; LUBIPROSTONE; MACROGOL; MAGNESIUM CITRATE; MAGNESIUM HYDROXIDE; MAGNESIUM SULFATE; METHYLCELLULOSE; NEUROTROPHIN 3; OPIATE ANTAGONIST; OSMOTIC AGENT; PICOSULFATE SODIUM; PLACEBO; POLYCARBOPHIL; PRUCALOPRIDE; RENZAPRIDE; SEROTONIN AGONIST; SODIUM DIHYDROGEN PHOSPHATE; SORBITOL; TD 5108; TEGASEROD; UNCLASSIFIED DRUG;

EID: 67349227863     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2008.12.006     Document Type: Review
Times cited : (91)

References (67)
  • 1
    • 10744229714 scopus 로고    scopus 로고
    • Prevalence of constipation: agreement among several criteria and evaluation of the diagnostic accuracy of qualifying symptoms and self-reported definition in a population-based survey in Spain
    • Garrigues V., Galvez C., Ortiz V., et al. Prevalence of constipation: agreement among several criteria and evaluation of the diagnostic accuracy of qualifying symptoms and self-reported definition in a population-based survey in Spain. Am J Epidemiol 159 (2004) 520-526
    • (2004) Am J Epidemiol , vol.159 , pp. 520-526
    • Garrigues, V.1    Galvez, C.2    Ortiz, V.3
  • 2
    • 0141653832 scopus 로고    scopus 로고
    • Chronic constipation
    • Lembo A., and Camilleri M. Chronic constipation. N Engl J Med 349 (2003) 1360-1368
    • (2003) N Engl J Med , vol.349 , pp. 1360-1368
    • Lembo, A.1    Camilleri, M.2
  • 3
    • 0035179716 scopus 로고    scopus 로고
    • An epidemiological survey of constipation in Canada: definitions, rates, demographics, and predictors of health care seeking
    • Pare P., Ferrazzi S., Thompson W., et al. An epidemiological survey of constipation in Canada: definitions, rates, demographics, and predictors of health care seeking. Am J Gastroenterol 96 (2001) 3130-3137
    • (2001) Am J Gastroenterol , vol.96 , pp. 3130-3137
    • Pare, P.1    Ferrazzi, S.2    Thompson, W.3
  • 4
    • 39749114602 scopus 로고    scopus 로고
    • The BI Omnibus study: an international survey of community prevalence of constipation and laxative use in adults
    • Wald A., Kamm M., Mueller-Lissner S., et al. The BI Omnibus study: an international survey of community prevalence of constipation and laxative use in adults. Gastroenterology 130 Suppl 2 (2006) 508
    • (2006) Gastroenterology , vol.130 , Issue.SUPPL. 2 , pp. 508
    • Wald, A.1    Kamm, M.2    Mueller-Lissner, S.3
  • 5
    • 0018955025 scopus 로고
    • Functional bowel disorders in apparently healthy people
    • Thompson W.G., and Heaton K.W. Functional bowel disorders in apparently healthy people. Gastroenterology 79 (1980) 283-288
    • (1980) Gastroenterology , vol.79 , pp. 283-288
    • Thompson, W.G.1    Heaton, K.W.2
  • 6
    • 34250870646 scopus 로고    scopus 로고
    • The burden of constipation on quality of life: results of a multinational survey
    • Wald A., Scarpignato C., Kamm M.A., et al. The burden of constipation on quality of life: results of a multinational survey. Aliment Pharmacol Ther 26 (2007) 227-236
    • (2007) Aliment Pharmacol Ther , vol.26 , pp. 227-236
    • Wald, A.1    Scarpignato, C.2    Kamm, M.A.3
  • 7
    • 33846981109 scopus 로고    scopus 로고
    • Chronic constipation: a survey of the patient perspective
    • Johanson J., and Kralstein J. Chronic constipation: a survey of the patient perspective. Aliment Pharmacol Ther 25 (2007) 599-608
    • (2007) Aliment Pharmacol Ther , vol.25 , pp. 599-608
    • Johanson, J.1    Kralstein, J.2
  • 9
    • 3042521504 scopus 로고    scopus 로고
    • New and emerging treatment options for chronic constipation
    • Schiller L.R. New and emerging treatment options for chronic constipation. Rev Gastroenterol Disord 4 Suppl 2 (2004) S43-S51
    • (2004) Rev Gastroenterol Disord , vol.4 , Issue.SUPPL. 2
    • Schiller, L.R.1
  • 10
    • 33644563019 scopus 로고    scopus 로고
    • Burden of chronic constipation must include estimates of work productivity and activity impairment in addition to traditional healthcare utilization
    • Bracco A., and Kahler K. Burden of chronic constipation must include estimates of work productivity and activity impairment in addition to traditional healthcare utilization. Am J Gastroenterol 99 Suppl 10 (2004) S233
    • (2004) Am J Gastroenterol , vol.99 , Issue.SUPPL. 10
    • Bracco, A.1    Kahler, K.2
  • 11
    • 0036677477 scopus 로고    scopus 로고
    • Health-related quality of life in functional GI disorders: focus on constipation and resource utilization
    • Irvine E.J., Ferrazzi S., Pare P., et al. Health-related quality of life in functional GI disorders: focus on constipation and resource utilization. Am J Gastroenterol 97 (2002) 1986-1993
    • (2002) Am J Gastroenterol , vol.97 , pp. 1986-1993
    • Irvine, E.J.1    Ferrazzi, S.2    Pare, P.3
  • 12
    • 0034464011 scopus 로고    scopus 로고
    • American Gastroenterological Association Medical Position Statement: guidelines on constipation
    • Locke III G., Pemberton J., and Phillips S. American Gastroenterological Association Medical Position Statement: guidelines on constipation. Gastroenterology 119 (2000) 1761-1766
    • (2000) Gastroenterology , vol.119 , pp. 1761-1766
    • Locke III, G.1    Pemberton, J.2    Phillips, S.3
  • 13
    • 22744432797 scopus 로고    scopus 로고
    • An evidence-based approach to the management of chronic constipation in North America
    • American College of Gastroenterology Chronic Constipation Task Force
    • American College of Gastroenterology Chronic Constipation Task Force. An evidence-based approach to the management of chronic constipation in North America. Am J Gastroenterol 100 (2005) S1-S4
    • (2005) Am J Gastroenterol , vol.100
  • 14
    • 33748482825 scopus 로고    scopus 로고
    • Effect of female sex hormone supplementation and withdrawal on gastrointestinal and colonic transit in postmenopausal women
    • Gonenne J., Esfandyari T., Camilleri M., et al. Effect of female sex hormone supplementation and withdrawal on gastrointestinal and colonic transit in postmenopausal women. Neurogastroenterol Motil 18 (2006) 911-918
    • (2006) Neurogastroenterol Motil , vol.18 , pp. 911-918
    • Gonenne, J.1    Esfandyari, T.2    Camilleri, M.3
  • 15
    • 34547509964 scopus 로고    scopus 로고
    • Abnormalities of prostaglandins and cyclooxygenase enzymes in female patients with slow-transit constipation
    • Cong P., Pricolo V., Biancani P., et al. Abnormalities of prostaglandins and cyclooxygenase enzymes in female patients with slow-transit constipation. Gastroenterology 133 (2007) 445-453
    • (2007) Gastroenterology , vol.133 , pp. 445-453
    • Cong, P.1    Pricolo, V.2    Biancani, P.3
  • 16
    • 15744393922 scopus 로고    scopus 로고
    • Role of progesterone signaling in the regulation of G-protein levels in female chronic constipation
    • Xiao Z.L., Pricolo V., Biancani P., et al. Role of progesterone signaling in the regulation of G-protein levels in female chronic constipation. Gastroenterology 128 (2005) 667-675
    • (2005) Gastroenterology , vol.128 , pp. 667-675
    • Xiao, Z.L.1    Pricolo, V.2    Biancani, P.3
  • 18
    • 22744440933 scopus 로고    scopus 로고
    • Clinical utility of diagnostic tests for constipation in adults: a systematic review
    • Rao S.S., Ozturk R., and Laine L. Clinical utility of diagnostic tests for constipation in adults: a systematic review. Am J Gastroenterol 100 (2005) 1605-1615
    • (2005) Am J Gastroenterol , vol.100 , pp. 1605-1615
    • Rao, S.S.1    Ozturk, R.2    Laine, L.3
  • 19
    • 0032829725 scopus 로고    scopus 로고
    • Functional bowel disorders and functional abdominal pain
    • Thompson W., Longstreth G., Drossman D., et al. Functional bowel disorders and functional abdominal pain. Gut 45 (1999) 1143-1147
    • (1999) Gut , vol.45 , pp. 1143-1147
    • Thompson, W.1    Longstreth, G.2    Drossman, D.3
  • 20
    • 33645568457 scopus 로고    scopus 로고
    • An Internet-based survey of the prevalence and symptom spectrum of chronic constipation
    • (abstr 723)
    • Schiller L., Dennis E., and Toth G. An Internet-based survey of the prevalence and symptom spectrum of chronic constipation. (abstr 723). Am J Gastroenterol 99 Suppl 10 (2004) S234
    • (2004) Am J Gastroenterol , vol.99 , Issue.SUPPL. 10
    • Schiller, L.1    Dennis, E.2    Toth, G.3
  • 21
    • 4444236480 scopus 로고    scopus 로고
    • Consensus on the guidelines for the diagnosis and treatment of chronic constipation
    • Chinese Society of Gastroenterology C.M.A. Consensus on the guidelines for the diagnosis and treatment of chronic constipation. Chin J Dig Dis 5 (2004) 134-137
    • (2004) Chin J Dig Dis , vol.5 , pp. 134-137
    • Chinese Society of Gastroenterology, C.M.A.1
  • 23
    • 47249148790 scopus 로고    scopus 로고
    • The role of biofeedback in the treatment of gastrointestinal disorders
    • Chiarioni G., and Whitehead W.E. The role of biofeedback in the treatment of gastrointestinal disorders. Nat Clin Pract Gastroenterol Hepatol 5 (2008) 371-382
    • (2008) Nat Clin Pract Gastroenterol Hepatol , vol.5 , pp. 371-382
    • Chiarioni, G.1    Whitehead, W.E.2
  • 24
    • 17544361897 scopus 로고    scopus 로고
    • Efficacy and safety of traditional medical therapies for chronic constipation: systematic review
    • Ramkumar D., and Rao S.S. Efficacy and safety of traditional medical therapies for chronic constipation: systematic review. Am J Gastroenterol 100 (2005) 936-971
    • (2005) Am J Gastroenterol , vol.100 , pp. 936-971
    • Ramkumar, D.1    Rao, S.S.2
  • 25
    • 0031048696 scopus 로고    scopus 로고
    • The treatment of chronic constipation in adults. A systematic review
    • Tramonte S., Brand M., Mulrow C., et al. The treatment of chronic constipation in adults. A systematic review. J Gen Intern Med 12 (1997) 15-24
    • (1997) J Gen Intern Med , vol.12 , pp. 15-24
    • Tramonte, S.1    Brand, M.2    Mulrow, C.3
  • 26
    • 0031860906 scopus 로고    scopus 로고
    • Psyllium is superior to docusate sodium for treatment of chronic constipation
    • McRorie J., Daggy B., Morel J., et al. Psyllium is superior to docusate sodium for treatment of chronic constipation. Aliment Pharmacol Ther 12 (1998) 491-497
    • (1998) Aliment Pharmacol Ther , vol.12 , pp. 491-497
    • McRorie, J.1    Daggy, B.2    Morel, J.3
  • 27
    • 0004463034 scopus 로고    scopus 로고
    • Systematic review of the effectiveness of laxatives in the elderly
    • i-iv
    • Petticrew M., Watt I., and Sheldon T. Systematic review of the effectiveness of laxatives in the elderly. Health Technol Assess 1 (1997) 1-52 i-iv
    • (1997) Health Technol Assess , vol.1 , pp. 1-52
    • Petticrew, M.1    Watt, I.2    Sheldon, T.3
  • 28
    • 0028237428 scopus 로고
    • Hypermagnesemia-induced paralytic ileus
    • Golzarian J., Scott Jr. H., and Richards W. Hypermagnesemia-induced paralytic ileus. Dig Dis Sci 39 (1994) 1138-1142
    • (1994) Dig Dis Sci , vol.39 , pp. 1138-1142
    • Golzarian, J.1    Scott Jr., H.2    Richards, W.3
  • 29
    • 22844441856 scopus 로고    scopus 로고
    • Systematic review on the management of chronic constipation in North America
    • Brandt L., Prather C., Quigley E., et al. Systematic review on the management of chronic constipation in North America. Am J Gastroenterol 100 (2005) S5-S22
    • (2005) Am J Gastroenterol , vol.100
    • Brandt, L.1    Prather, C.2    Quigley, E.3
  • 31
    • 27644510180 scopus 로고    scopus 로고
    • Double-blind randomized evaluation of clinical and biological tolerance of polyethylene glycol 4000 versus lactulose in constipated children
    • Dupont C., Leluyer B., Maamri N., et al. Double-blind randomized evaluation of clinical and biological tolerance of polyethylene glycol 4000 versus lactulose in constipated children. J Pediatr Gastroenterol Nutr 41 (2005) 625-633
    • (2005) J Pediatr Gastroenterol Nutr , vol.41 , pp. 625-633
    • Dupont, C.1    Leluyer, B.2    Maamri, N.3
  • 32
    • 0025109518 scopus 로고
    • Cost-effective treatment of constipation in the elderly: a randomized double-blind comparison of sorbitol and lactulose
    • Lederle F., Busch D., Mattox K., et al. Cost-effective treatment of constipation in the elderly: a randomized double-blind comparison of sorbitol and lactulose. Am J Med 89 (1990) 597-601
    • (1990) Am J Med , vol.89 , pp. 597-601
    • Lederle, F.1    Busch, D.2    Mattox, K.3
  • 33
    • 0033967018 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, multicenter study of the safety and efficacy of a new polyethylene glycol laxative
    • Di Palma J., DeRidder P., Orlando R., et al. A randomized, placebo-controlled, multicenter study of the safety and efficacy of a new polyethylene glycol laxative. Am J Gastroenterol 95 (2000) 446-450
    • (2000) Am J Gastroenterol , vol.95 , pp. 446-450
    • Di Palma, J.1    DeRidder, P.2    Orlando, R.3
  • 34
    • 0036314325 scopus 로고    scopus 로고
    • Overnight efficacy of polyethylene glycol laxative
    • Di Palma J., Smith J., and Cleveland M. Overnight efficacy of polyethylene glycol laxative. Am J Gastroenterol 97 (2002) 1776-1779
    • (2002) Am J Gastroenterol , vol.97 , pp. 1776-1779
    • Di Palma, J.1    Smith, J.2    Cleveland, M.3
  • 35
    • 34548139322 scopus 로고    scopus 로고
    • A randomized, multicenter comparison of polyethylene glycol laxative and tegaserod in treatment of patients with chronic constipation
    • Di Palma J., Cleveland M., McGowan J., et al. A randomized, multicenter comparison of polyethylene glycol laxative and tegaserod in treatment of patients with chronic constipation. Am J Gastroenterol 102 (2007) 1964-1971
    • (2007) Am J Gastroenterol , vol.102 , pp. 1964-1971
    • Di Palma, J.1    Cleveland, M.2    McGowan, J.3
  • 36
    • 37549040228 scopus 로고    scopus 로고
    • Differences in taste between two polyethylene glycol preparations
    • Szojda M.M., Mulder C.J., and Felt-Bersma R.J. Differences in taste between two polyethylene glycol preparations. J Gastrointest Liver Dis 16 (2007) 379-381
    • (2007) J Gastrointest Liver Dis , vol.16 , pp. 379-381
    • Szojda, M.M.1    Mulder, C.J.2    Felt-Bersma, R.J.3
  • 37
    • 33745685698 scopus 로고    scopus 로고
    • Long-term efficacy and cost-effectiveness of polyethylene glycol 3350 plus electrolytes in chronic constipation: a retrospective study in a disabled population
    • Migeon-Duballet I., Chabin M., Gautier A., et al. Long-term efficacy and cost-effectiveness of polyethylene glycol 3350 plus electrolytes in chronic constipation: a retrospective study in a disabled population. Curr Med Res Opin 22 (2006) 1227-1235
    • (2006) Curr Med Res Opin , vol.22 , pp. 1227-1235
    • Migeon-Duballet, I.1    Chabin, M.2    Gautier, A.3
  • 38
    • 33748423741 scopus 로고    scopus 로고
    • A randomized, prospective, comparison study of polyethylene glycol 3350 without electrolytes and milk of magnesia for children with constipation and fecal incontinence
    • Loening-Baucke V., and Pashankar D. A randomized, prospective, comparison study of polyethylene glycol 3350 without electrolytes and milk of magnesia for children with constipation and fecal incontinence. Pediatrics 118 (2006) 528-535
    • (2006) Pediatrics , vol.118 , pp. 528-535
    • Loening-Baucke, V.1    Pashankar, D.2
  • 39
    • 34250897567 scopus 로고    scopus 로고
    • A randomized, multicenter, placebo-controlled trial of polyethylene glycol laxative for chronic treatment of chronic constipation
    • Dipalma J.A., Cleveland M.V., McGowan J., et al. A randomized, multicenter, placebo-controlled trial of polyethylene glycol laxative for chronic treatment of chronic constipation. Am J Gastroenterol 102 (2007) 1436-1441
    • (2007) Am J Gastroenterol , vol.102 , pp. 1436-1441
    • Dipalma, J.A.1    Cleveland, M.V.2    McGowan, J.3
  • 40
    • 10344243993 scopus 로고    scopus 로고
    • The treatment of chronic constipation in elderly people: an update
    • Bosshard W., Dreher R., Schnegg J., et al. The treatment of chronic constipation in elderly people: an update. Drugs Aging 21 (2004) 911-930
    • (2004) Drugs Aging , vol.21 , pp. 911-930
    • Bosshard, W.1    Dreher, R.2    Schnegg, J.3
  • 41
    • 27744514047 scopus 로고
    • Langzeitbehandung mit einem pflanzlichen laxitivum. Serumelektroyte und saeurenbasenhaushalt
    • Heiny B.M. Langzeitbehandung mit einem pflanzlichen laxitivum. Serumelektroyte und saeurenbasenhaushalt. Arztliche Praxis 28 (1976) 563-564
    • (1976) Arztliche Praxis , vol.28 , pp. 563-564
    • Heiny, B.M.1
  • 42
    • 34247370973 scopus 로고    scopus 로고
    • Comparison of bisacodyl and sodium picosulphate in the treatment of chronic constipation
    • Kienzle-Horn S., Vix J.M., Schuijt C., et al. Comparison of bisacodyl and sodium picosulphate in the treatment of chronic constipation. Curr Med Res Opin 23 (2007) 691-699
    • (2007) Curr Med Res Opin , vol.23 , pp. 691-699
    • Kienzle-Horn, S.1    Vix, J.M.2    Schuijt, C.3
  • 43
    • 0019182076 scopus 로고
    • Dauerbehandlung mit laxantien
    • Rosprich G. Dauerbehandlung mit laxantien. Therapiewoche 30 (1980) 5836-5837
    • (1980) Therapiewoche , vol.30 , pp. 5836-5837
    • Rosprich, G.1
  • 44
    • 17844366548 scopus 로고    scopus 로고
    • Psychological well-being and symptoms in women with chronic constipation treated with sodium picosulphate
    • Bengtsson M., and Ohlsson B. Psychological well-being and symptoms in women with chronic constipation treated with sodium picosulphate. Gastroenterol Nurs 28 (2005) 3-12
    • (2005) Gastroenterol Nurs , vol.28 , pp. 3-12
    • Bengtsson, M.1    Ohlsson, B.2
  • 45
    • 27744547717 scopus 로고
    • Laxanzien-langzeittherapie mit bisacodyl. Wirksamkeit und verträglicheit bei patienten mit rückenmarkverletzungen
    • Ruidisch M.H., Hutt H.-J., and König E. Laxanzien-langzeittherapie mit bisacodyl. Wirksamkeit und verträglicheit bei patienten mit rückenmarkverletzungen. Arztliche Forschung 41 (1994) 3-8
    • (1994) Arztliche Forschung , vol.41 , pp. 3-8
    • Ruidisch, M.H.1    Hutt, H.-J.2    König, E.3
  • 47
    • 0038747009 scopus 로고    scopus 로고
    • Treatment of chronic constipation with colchicine: randomized, double-blind, placebo-controlled, crossover trial
    • Verne G.N., Davis R.H., Robinson M.E., et al. Treatment of chronic constipation with colchicine: randomized, double-blind, placebo-controlled, crossover trial. Am J Gastroenterol 98 (2003) 1112-1116
    • (2003) Am J Gastroenterol , vol.98 , pp. 1112-1116
    • Verne, G.N.1    Davis, R.H.2    Robinson, M.E.3
  • 48
    • 0038796092 scopus 로고    scopus 로고
    • Nighttime heartburn is an under-appreciated clinical problem that impacts sleep and daytime function: the results of a Gallup Survey conducted on behalf of the American Gastroenterological Association
    • Shaker R., Castell D.O., Schoenfeld P.S., and Spechler S.J. Nighttime heartburn is an under-appreciated clinical problem that impacts sleep and daytime function: the results of a Gallup Survey conducted on behalf of the American Gastroenterological Association. Am J Gastroenterol 98 (2003) 1112-1116
    • (2003) Am J Gastroenterol , vol.98 , pp. 1112-1116
    • Shaker, R.1    Castell, D.O.2    Schoenfeld, P.S.3    Spechler, S.J.4
  • 49
    • 46049098356 scopus 로고    scopus 로고
    • The Food and Drug Administration approves methylnaltrexone bromide for opioid-induced constipation
    • Lang L. The Food and Drug Administration approves methylnaltrexone bromide for opioid-induced constipation. Gastroenterology 135 (2008) 6
    • (2008) Gastroenterology , vol.135 , pp. 6
    • Lang, L.1
  • 50
    • 44349145194 scopus 로고    scopus 로고
    • Methylnaltrexone for opioid-induced constipation in advanced illness
    • Thomas J., Karver S., Cooney G.A., et al. Methylnaltrexone for opioid-induced constipation in advanced illness. N Engl J Med 358 (2008) 2332-2343
    • (2008) N Engl J Med , vol.358 , pp. 2332-2343
    • Thomas, J.1    Karver, S.2    Cooney, G.A.3
  • 51
    • 33846424151 scopus 로고    scopus 로고
    • Alvimopan, a peripherally acting mu-opioid receptor (PAM-OR) antagonist-a study in patients with chronic idiopathic constipation (CIC) not taking opioid medications
    • (abstr 1239)
    • Kelleher D., Johanson J., Pobiner B., et al. Alvimopan, a peripherally acting mu-opioid receptor (PAM-OR) antagonist-a study in patients with chronic idiopathic constipation (CIC) not taking opioid medications. (abstr 1239). Am J Gastroenterol 101 (2006) S480
    • (2006) Am J Gastroenterol , vol.101
    • Kelleher, D.1    Johanson, J.2    Pobiner, B.3
  • 52
    • 0037973518 scopus 로고    scopus 로고
    • Neurotrophin-3 improves functional constipation
    • Parkman H., Rao S., Reynolds J., et al. Neurotrophin-3 improves functional constipation. Am J Gastroenterol 98 (2003) 1338-1347
    • (2003) Am J Gastroenterol , vol.98 , pp. 1338-1347
    • Parkman, H.1    Rao, S.2    Reynolds, J.3
  • 53
    • 37849024665 scopus 로고    scopus 로고
    • Multicenter, 4-week, double-blind, randomized, placebo-controlled trial of lubiprostone, a locally-acting type-2 chloride channel activator, in patients with chronic constipation
    • Johanson J.F., Morton D., Geenen J., et al. Multicenter, 4-week, double-blind, randomized, placebo-controlled trial of lubiprostone, a locally-acting type-2 chloride channel activator, in patients with chronic constipation. Am J Gastroenterol 103 (2008) 170-177
    • (2008) Am J Gastroenterol , vol.103 , pp. 170-177
    • Johanson, J.F.1    Morton, D.2    Geenen, J.3
  • 54
    • 0033000111 scopus 로고    scopus 로고
    • Guanylin regulatory peptides: structures, biological activities mediated by cyclic gmp and pathobiology
    • Forte L.R. Guanylin regulatory peptides: structures, biological activities mediated by cyclic gmp and pathobiology. Regul Pept 81 (1999) 25-39
    • (1999) Regul Pept , vol.81 , pp. 25-39
    • Forte, L.R.1
  • 55
    • 67349144156 scopus 로고    scopus 로고
    • Effect of 5 days linaclotide on transit and bowel function in females with constipation-predominant irritable bowel syndrome
    • Andresen V., Camilleri M., Busciglio I.A., et al. Effect of 5 days linaclotide on transit and bowel function in females with constipation-predominant irritable bowel syndrome. Gastroenterology 33 (2007) 61-68
    • (2007) Gastroenterology , vol.33 , pp. 61-68
    • Andresen, V.1    Camilleri, M.2    Busciglio, I.A.3
  • 56
    • 0033258353 scopus 로고    scopus 로고
    • Review article: cardiac adverse effects of gastrointestinal prokinetics
    • Tonini M., de Ponti F., di Nucci A., et al. Review article: cardiac adverse effects of gastrointestinal prokinetics. Aliment Pharmacol Ther 13 (1999) 1585-1591
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 1585-1591
    • Tonini, M.1    de Ponti, F.2    di Nucci, A.3
  • 58
    • 4444245748 scopus 로고    scopus 로고
    • Effect of tegaserod in chronic constipation: a randomized, double-blind, controlled trial
    • Johanson J.F., Wald A., Tougas G., et al. Effect of tegaserod in chronic constipation: a randomized, double-blind, controlled trial. Clin Gastroenterol Hepatol 2 (2004) 796-805
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 796-805
    • Johanson, J.F.1    Wald, A.2    Tougas, G.3
  • 59
    • 44949106525 scopus 로고    scopus 로고
    • Tegaserod for the treatment of irritable bowel syndrome and chronic constipation
    • CD003960
    • Evans B.W., Clark W.K., Moore D.J., et al. Tegaserod for the treatment of irritable bowel syndrome and chronic constipation. Cochrane Database Syst Rev 4 (2007) CD003960
    • (2007) Cochrane Database Syst Rev , vol.4
    • Evans, B.W.1    Clark, W.K.2    Moore, D.J.3
  • 60
    • 0035967979 scopus 로고    scopus 로고
    • The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound
    • Briejer M.R., Bosmans J.P., Van Daele P., et al. The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. Eur J Pharmacol 423 (2001) 71-83
    • (2001) Eur J Pharmacol , vol.423 , pp. 71-83
    • Briejer, M.R.1    Bosmans, J.P.2    Van Daele, P.3
  • 61
    • 0033005188 scopus 로고    scopus 로고
    • Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans
    • Bouras E.P., Camilleri M., Burton D.D., et al. Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans. Gut 44 (1999) 682-686
    • (1999) Gut , vol.44 , pp. 682-686
    • Bouras, E.P.1    Camilleri, M.2    Burton, D.D.3
  • 62
    • 0035121508 scopus 로고    scopus 로고
    • Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder
    • Bouras E.P., Camilleri M., Burton D.D., et al. Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder. Gastroenterology 120 (2001) 354-360
    • (2001) Gastroenterology , vol.120 , pp. 354-360
    • Bouras, E.P.1    Camilleri, M.2    Burton, D.D.3
  • 63
    • 67349156115 scopus 로고    scopus 로고
    • Prucalopride (resolor (R)) in the treatment of severe chronic constipation in patients dissatisfied with laxatives
    • [Epub ahead of press]
    • Tack J., Van Outryve M., Beyens G., et al. Prucalopride (resolor (R)) in the treatment of severe chronic constipation in patients dissatisfied with laxatives. Gut (2008) [Epub ahead of press]
    • (2008) Gut
    • Tack, J.1    Van Outryve, M.2    Beyens, G.3
  • 64
    • 44349130441 scopus 로고    scopus 로고
    • A placebo-controlled trial of prucalopride for severe chronic constipation
    • Camilleri M., Kerstens R., Rykx A., et al. A placebo-controlled trial of prucalopride for severe chronic constipation. N Engl J Med 358 (2008) 2344-2354
    • (2008) N Engl J Med , vol.358 , pp. 2344-2354
    • Camilleri, M.1    Kerstens, R.2    Rykx, A.3
  • 66
    • 33646544729 scopus 로고    scopus 로고
    • Pilot study of the efficacy of renzapride on gastrointestinal motility and symptoms in patients with constipation-predominant irritable bowel syndrome
    • Tack J., Middleton S.J., Horne M.C., et al. Pilot study of the efficacy of renzapride on gastrointestinal motility and symptoms in patients with constipation-predominant irritable bowel syndrome. Aliment Pharmacol Ther 23 (2006) 1655-1665
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 1655-1665
    • Tack, J.1    Middleton, S.J.2    Horne, M.C.3
  • 67
    • 42749106122 scopus 로고    scopus 로고
    • Laxatives for the management of constipation in palliative care patients
    • CD003448
    • Miles C., Fellowes D., Goodman M., et al. Laxatives for the management of constipation in palliative care patients. Cochrane Database Syst Rev 4 (2006) CD003448
    • (2006) Cochrane Database Syst Rev , vol.4
    • Miles, C.1    Fellowes, D.2    Goodman, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.