Intervention of astaxanthin against cyclophosphamide-induced oxidative stress and DNA damage: A study in mice

Chemico-Biological Interactions

Volumn 180, Issue 3, 2009, Pages 398-406

  Tripathi, D N ^a   Jena, G B ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Astaxanthin; Comet assay; Cyclophosphamide; End III; FPG; Micronucleus; Oxidative stress

Indexed keywords

ASTAXANTHIN; CYCLOPHOSPHAMIDE; DNA; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; ENDONUCLEASE; GLUTATHIONE; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BONE MARROW; CHROMOSOME ABERRATION; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; LIVER PARENCHYMA; MALE; MICRONUCLEUS TEST; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PERIPHERAL LYMPHOCYTE;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; COMET ASSAY; CYCLOPHOSPHAMIDE; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; LIPID PEROXIDATION; MALONDIALDEHYDE; MICE; MICRONUCLEUS TESTS; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE; XANTHOPHYLLS;

MUS;

EID: 67349224618     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.03.017     Document Type: Article

References (54)

1. Bendich A., and Olson J.A. Biological actions of carotenoids. FASEB J. 3 8 (1989) 1927-1932
2. Jyonouchi H., Zhang L., Gross M., and Tomita Y. Immunomodulating actions of carotenoids: enhancement of in vivo and in vitro antibody production to T-dependent antigens. Nutr. Cancer 21 1 (1994) 47-58
3. Tanaka T., Morishita Y., Suzui M., Kojima T., Okumura A., and Mori H. Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin. Carcinogenesis 15 1 (1994) 15-19
4. Lorenz R.T., and Cysewski G.R. Commercial potential for Haematococcus microalgae as a natural source of astaxanthin. Trends Biotechnol. 18 4 (2000) 160-167
5. Goto S., Kogure K., Abe K., Kimata Y., Kitahama K., Yamashita E., and Terada H. Efficient radical trapping at the surface and inside the phospholipid membrane is responsible for highly potent antiperoxidative activity of the carotenoid astaxanthin. Biochim. Biophys. Acta 1512 2 (2001) 251-258
6. Bennedsen M., Wang X., Willen R., Wadstrom T., and Andersen L.P. Treatment of H. pylori infected mice with antioxidant astaxanthin reduces gastric inflammation, bacterial load and modulates cytokine release by splenocytes. Immunol. Lett. 70 3 (1999) 185-189
7. Pashkow F.J., Watumull D.G., and Campbell C.L. Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease. Am. J Cardiol. 101 10A (2008) 58D-68D
8. Kurihara H., Koda H., Asami S., Kiso Y., and Tanaka T. Contribution of the antioxidative property of astaxanthin to its protective effect on the promotion of cancer metastasis in mice treated with restraint stress. Life Sci. 70 21 (2002) 2509-2520
9. Kamath B.S., Srikanta B.M., Dharmesh S.M., Sarada R., and Ravishankar G.A. Ulcer preventive and antioxidative properties of astaxanthin from Haematococcus pluvialis. Eur. J. Pharmacol. 590 1-3 (2008) 387-395
10. Hussein G., Goto H., Oda S., Sankawa U., Matsumoto K., and Watanabe H. Antihypertensive potential and mechanism of action of astaxanthin: III. Antioxidant and histopathological effects in spontaneously hypertensive rats. Biol. Pharm. Bull. 29 4 (2006) 684-688
11. Ikeuchi M., Koyama T., Takahashi J., and Yazawa K. Effects of astaxanthin supplementation on exercise-induced fatigue in mice. Biol. Pharm. Bull. 29 10 (2006) 2106-2110
12. Zhang X., Pan L., Wei X., Gao H., and Liu J. Impact of astaxanthin-enriched algal powder of Haematococcus pluvialis on memory improvement in BALB/c mice. Environ. Geochem. Health 29 6 (2007) 483-489
13. Ikeuchi M., Koyama T., Takahashi J., and Yazawa K. Effects of astaxanthin in obese mice fed a high-fat diet. Biosci. Biotechnol. Biochem. 71 4 (2007) 893-899
14. Hix L.M., Frey D.A., McLaws M.D., Osterlie M., Lockwood S.F., and Bertram J.S. Inhibition of chemically-induced neoplastic transformation by a novel tetrasodium diphosphate astaxanthin derivative. Carcinogenesis 26 9 (2005) 1634-1641
15. H. Shen, C.C. Kuo, J. Chou, A. Delvolve, S.N. Jackson, J. Post, A.S. Woods, B.J. Hoffer, Y. Wang, B.K. Harvey, Astaxanthin reduces ischemic brain injury in adult rats, FASEB J., 2009, in press.
16. de la Mora G.I., Arredondo-Figueroa J.L., Barriga-Sosa Ide L., Bazan-Arias J., and Vernon-Carter J. Effects of the dietary incorporation of carotenoid pigments on gonad development and oocyte maturity in females of rainbow trout. Arch. Latinoam. Nutr. 54 2 (2004) 235-240
17. Tripathi D.N., and Jena G.B. Astaxanthin inhibits cytotoxic and genotoxic effects of cyclophosphamide in mice germ cells. Toxicology 248 2-3 (2008) 96-103
18. Fiorucci E., Lucantoni G., Paone G., Zotti M., Li B.E., Serpilli M., Regimenti P., Cammarella I., Puglisi G., and Schmid G. Colchicine, cyclophosphamide and prednisone in the treatment of mild-moderate idiopathic pulmonary fibrosis: comparison of three currently available therapeutic regimens. Eur. Rev. Med. Pharmacol. Sci. 12 2 (2008) 105-111
19. Fraiser L.H., Kanekal S., and Kehrer J.P. Cyclophosphamide toxicity. Characterising and avoiding the problem. Drugs 42 5 (1991) 781-795
20. Borgmann A., Zinn C., Hartmann R., Herold R., Kaatsch P., Escherich G., Moricke A., Henze G., and von Stackelberg A. Secondary malignant neoplasms after intensive treatment of relapsed acute lymphoblastic leukaemia in childhood. Eur. J. Cancer 44 2 (2008) 257-268
21. IARC, IARC Monograph on the evaluation of carcinogenicity: an update of IARC monographs 1 to 42, International Agency for Research on Cancer Supplement 7, 1987.
22. Rekhadevi P.V., Sailaja N., Chandrasekhar M., Mahboob M., Rahman M.F., and Grover P. Genotoxicity assessment in oncology nurses handling anti-neoplastic drugs. Mutagenesis 22 6 (2007) 395-401
23. Roy P., Yu L.J., Crespi C.L., and Waxman D.J. Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles. Drug Metab. Dispos. 27 6 (1999) 655-666
24. Korkmaz A., Topal T., and Oter S. Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation. Cell Biol. Toxicol. 12 47 (2007) 27
25. Ferguson L.R., and Pearson A.E. The clinical use of mutagenic anticancer drugs. Mutat. Res. 355 1-2 (1996) 1-12
26. Kim J.H., Kim Y.S., Song G.G., Park J.J., and Chang H.I. Protective effect of astaxanthin on naproxen-induced gastric antral ulceration in rats. Eur. J Pharmacol. 514 1 (2005) 53-59
27. Ohkawa H., Ohishi N., and Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95 2 (1979) 351-358
28. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin phenol reagent. J Biol. Chem. 193 1 (1951) 265-275
29. Paoletti F., Aldinucci D., Mocali A., and Caparrini A. A sensitive spectrophotometric method for the determination of superoxide dismutase activity in tissue extracts. Anal. Biochem. 154 2 (1986) 536-541
30. Moron M.S., Depierre J.W., and Mannervik B. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochim. Biophys. Acta 582 1 (1979) 67-78
31. Singh N.P., McCoy M.T., Tice R.R., and Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175 1 (1988) 184-191
32. Collins A.R., Duthie S.J., and Dobson V.L. Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA. Carcinogenesis 14 9 (1993) 1733-1735
33. Holden H.E., Majeska J.B., and Studwell D. A direct comparison of mouse and rat bone marrow and blood as target tissues in the micronucleus assay. Mutat. Res. 391 1-2 (1997) 87-89
34. Preston R.J., Dean B.J., Galloway S., Holden H., McFee A.F., and Shelby M. Mammalian in vivo cytogenetic assays. Analysis of chromosome aberrations in bone marrow cells. Mutat. Res. 189 2 (1987) 157-165
35. Tripathi D.N., and Jena G.B. Ebselen attenuates cyclophosphamide-induced oxidative stress and DNA damage in mice. Free Radic. Res. 42 11 (2008) 966-977
36. Perry C.S., Liu X., Lund L.G., Whitman C.P., and Kehrer J.P. Differential toxicities of cyclophosphamide and its glutathione metabolites to A549 cells. Toxicol. In Vitro 9 1 (1995) 21-26
37. Adams Jr. J.D., and Klaidman L.K. Acrolein-induced oxygen radical formation. Free Radic. Biol. Med. 15 2 (1993) 187-193
38. Stankiewicz A., Skrzydlewska E., Sulkowska M., and Sulkowski S. Effect of amifostine on lung oxidative stress after cyclophosphamide therapy. Bull. Vet. Inst. Pulawy 49 (2002) 87-94
39. Haenen G.R., Vermeulen N.P., Tail Tin Tsoi J.N., Ragetli H.M., Timmerman H., and Blast A. Activation of the microsomal glutathione-S-transferase and reduction of the glutathione dependent protection against lipid peroxidation by acrolein. Biochem. Pharmacol. 37 (1988) 1933-1938
40. Zhang Q.H., Wu C.F., Duan L., and Yang J.Y. Protective effects of ginsenoside Rg(3) against cyclophosphamide-induced DNA damage and cell apoptosis in mice. Arch. Toxicol. 82 2 (2008) 117-123
41. Dumontet C., Drai J., Thieblemont C., Hequet O., Espinouse D., Bouafia F., Salles G., and Coiffier B. The superoxide dismutase content in erythrocytes predicts short-term toxicity of high-dose cyclophosphamide. Br. J Haematol. 112 2 (2001) 405-409
42. Miki W. Biological functions and activities of animal carotenoids. Pure Appl. Chem. 63 1 (1991) 141-146
43. Tiku A.B., Abraham S.K., and Kale R.K. Protective effect of the cruciferous vegetable mustard leaf (Brassica campestris) against in vivo chromosomal damage and oxidative stress induced by gamma-radiation and genotoxic chemicals. Environ. Mol. Mutagen. 49 5 (2008) 335-342
44. Bhatia K., Ahmad F., Rashid H., and Raisuddin S. Protective effect of S-allylcysteine against cyclophosphamide-induced bladder hemorrhagic cystitis in mice. Food Chem. Toxicol. 46 11 (2008) 3368-3374
45. Sun H.X., and Peng X.Y. Protective effect of triterpenoid fractions from the rhizomes of Astilbe chinensis on cyclophosphamide-induced toxicity in tumor-bearing mice. J. Ethnopharmacol. 119 2 (2008) 312-317
46. Santocono M., Zurria M., Berrettini M., Fedeli D., and Falcioni G. Influence of astaxanthin, zeaxanthin and lutein on DNA damage and repair in UVA-irradiated cells. J Photochem. Photobiol. B 85 3 (2006) 205-215
47. E. Camera, A. Matrofrancesco, C. Fabbri, F. Daubrawa, M. Picardo, H. Sies, W. Stahl, Astaxanthin, canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes, Exp. Dermatol., 2008, in press.
48. Ikeda Y., Tsuji S., Satoh A., Ishikura M., Shirasawa T., and Shimizu T. Protective effects of astaxanthin on 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells. J. Neurochem. 107 6 (2008) 1730-1740
49. Manabe E., Handa O., Naito Y., Mizushima K., Akagiri S., Adachi S., Takagi T., Kokura S., Maoka T., and Yoshikawa T. Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling. J. Cell Biochem. 103 6 (2008) 1925-1937
50. Hix L.M., Lockwood S.F., and Bertram J.S. Upregulation of connexin 43 protein expression and increased gap junctional communication by water soluble disodium disuccinate astaxanthin derivatives. Cancer Lett. 211 1 (2004) 25-37
51. Ben-Dor A., Steiner M., Gheber L., Danilenko M., Dubi N., Linnewiel K., Zick A., Sharoni Y., and Levy J. Carotenoids activate the antioxidant response element transcription system. Mol. Cancer Ther. 4 1 (2005) 177-186
52. Conklin K.A. Cancer chemotherapy and antioxidants. J. Nutr. 134 11 (2004) 3201S-3204S
53. Tanguay C., Harvey I., Houde M., Srigley J.R., and Tetu B. Leiomyosarcoma of urinary bladder following cyclophosphamide therapy: report of two cases. Mod. Pathol. 16 5 (2003) 512-514
54. Cohen S.M., Garland E.M., St John M., Okamura T., and Smith R.A. Acrolein initiates rat urinary bladder carcinogenesis. Cancer Res. 52 13 (1992) 3577-3581