Randomized Trial of Emergency Endoscopic Sclerotherapy Versus Emergency Portacaval Shunt for Acutely Bleeding Esophageal Varices in Cirrhosis

Journal of the American College of Surgeons

Volumn 209, Issue 1, 2009, Pages 25-40

  Orloff, Marshall J ^a   Isenberg, Jon I ^a   Wheeler, Henry O ^a   Haynes, Kevin S ^a   Jinich Brook, Horacio ^a   Rapier, Roderick ^a   Vaida, Florin ^a   Hye, Robert J ^a  

^a UCSD MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BLOOD TRANSFUSION; BRAIN DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EMERGENCY SURGERY; ENDOSCOPIC SCLEROTHERAPY; ESOPHAGUS VARICES BLEEDING; FEMALE; FOLLOW UP; HUMAN; INTERMETHOD COMPARISON; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; PORTOCAVAL SHUNT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SURVIVAL RATE; UPPER GASTROINTESTINAL BLEEDING;

ADULT; AGED; AGED, 80 AND OVER; BLOOD TRANSFUSION; EMERGENCY TREATMENT; ENDOSCOPY; ESOPHAGEAL AND GASTRIC VARICES; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PORTACAVAL SHUNT, SURGICAL; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; SCLEROTHERAPY; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 67349219107     PISSN: 10727515     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2009.02.059     Document Type: Article

References (52)

1. Graham D.Y., and Smith H. The course of patients after variceal hemorrhage. Gastroenterology 80 (1981) 800-809
2. Smith J.L., and Graham D.Y. Variceal hemorrhage: a critical evaluation of survival analysis. Gastroenterology 82 (1982) 968-973
3. Burroughs A.K., Mezzanotte G., Phillips A., et al. Cirrhotics with variceal hemorrhage: the importance of the time interval between admission and the start of analysis for survival and rebleeding rates. Hepatology 9 (1969) 801-807
4. Bornman P.C., Krige J.E., and Terblanche J. Management of oesophageal varices. Lancet 353 (1994) 1079-1084
5. Khan S, Tudur Smith C, Williamson P, Sutton R. Portosystemic shunts versus endoscopic therapy for variceal rebleeding in patients with cirrhosis. Cochrane Database of Systematic Reviews 2006, Issue 1. Art. No. CD000553. DOI: 10.1002/14651858. CD000553. Pub 2.
6. Orloff M.J., Duguay L.R., and Kosta L.D. Criteria for selection of patients for emergency portacaval shunt. Am J Surg 134 (1977) 146-152
7. Mikkelsen W.P. Therapeutic portacaval shunt. Preliminary data on controlled trial and morbid effects of acute hyaline necrosis. Arch Surg 108 (1974) 302-305
8. Terblanche J., Burroughs A.K., and Hobbs K.E.F. Controversies in the management of bleeding oesophageal varices. N Engl J Med 320 (1989) 1393-1398
9. D'Amico G., Pagliaro L., and Bosch J. The treatment of portal hypertension: a meta-analytic review. Hepatology 22 (1995) 332-354
10. Cello P., Brendell J.H., Crass R.A., et al. Endoscopic sclerotherapy versus portacaval shunt in patients with severe cirrhosis and variceal hemorrhage. N Engl J Med 311 (1984) 1589-1594
11. Cello J.P., Grendell J.H., Crass R.A., et al. Endoscopic sclerotherapy versus portacaval shunt in patients with severe cirrhosis and acute variceal hemorrhage. Long-term follow-up. N Engl J Med 316 (1987) 11-15
12. Orloff M.J. Emergency portacaval shunt: a comparative study of shunt, varix ligation, and nonsurgical treatment of bleeding esophageal varices in unselected patients with cirrhosis. Ann Surg 166 (1967) 456-478
13. Orloff M.J., Bell Jr. R.H., Hyde P.V., and Skovolocki W.P. Long-term results of emergency portacaval shunt for bleeding esophageal varices in unselected patients with alcohol cirrhosis. Ann Surg 192 (1980) 325-340
14. Orloff M.J., Orloff M.S., Rambotti M., and Girard B. Is portal-systemic shunt worthwhile in Child's class C cirrhosis: Long-term results of emergency shunt in 94 patients with bleeding varices. Ann Surg 216 (1992) 256-268
15. Orloff M.J., Bell Jr. R.H., Orloff M.S., et al. Prospective randomized trial of emergency portacaval shunt and emergency medical therapy in unselected cirrhotic patients with bleeding varices. Hepatology 20 (1994) 863-872
16. Orloff M.J., Orloff M.S., Orloff S.L., et al. Three decades of experience with emergency portacaval shunt for acutely bleeding esophageal varices in 400 unselected patients with cirrhosis of the liver. J Am Coll Surg 180 (1995) 257-272
17. Moher D., Schulz K.F., and Altman D. The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. JAMA 285 (2001) 1987-1991
18. Altman D.G., Schulz K.F., Moher D., et al. The revised CONSORT statement for reporting randomized trials: explanation and elaboration. Ann Intern Med 134 (2001) 663-694
19. Orloff M.J., Orloff S.L., and Orloff M.S. Portacaval shunts: side-to-side and end-to-side. In: Clavien P.-A., Saar M.G., and Fong Y. (Eds). Atlas of upper gastrointestinal and hepato-pancreato-biliary surgery (2007), Springer-Verlag, Berlin Heidelberg 687-702
20. Conn H.O., and Liberthal M.M. The hepatic coma syndromes and lactulose (1978), Williams & Wilkins, Baltimore
21. Child III C.G., and Turcotte J.G. Surgery and portal hypertension. In: Child III C.G. (Ed). The liver and portal hypertension (1964), WB Saunders, Philadelphia 1-85
22. Campbell D.P., Parker D.E., and Anagnostopoulos C.E. Survival prediction in portacaval shunt: a computerized statistical analysis. Am J Surg 126 (1973) 748-751
23. Korula J., Yelin A., Yamada S., et al. A prospective randomized controlled comparison of chronic endoscopic variceal sclerotherapy and portalsystemic shunt for variceal hemorrhage in Child's class A cirrhotics: a preliminary report. Gastroenterology 92 (1987) 1745
24. Planas R., Boix J., Broggi M., et al. Portacaval shunt versus endoscopic sclerotherapy in the elective treatment of variceal hemorrhage. Gastroenterology 100 (1991) 1078-1086
25. Isaksson B., Jeppsson B., Gengtsson F., et al. Mesocaval shunt or repeated sclerotherapy: effects on rebleeding and encephalopathy-a randomized trial. Surgery 117 (1995) 498-504
26. Henderson J.M., Kutner M.H., Millikan W.J., et al. Endoscopic variceal sclerosis compared with distal splenorenal shunt to prevent recurrent variceal bleeding in cirrhosis, a prospective randomized trial. Ann Intern Med 112 (1990) 262-269
27. Rikkers L.F., Burnett D.A., Volentine G.D., et al. Shunt surgery versus endoscopic sclerotherapy for long-term treatment of variceal bleeding. Early results of a randomized trial. Ann Surg 206 (1987) 261-271
28. Rikkers L.F., Jin G., Burnett D.A., et al. Shunt surgery versus endoscopic sclerotherapy for variceal hemorrhage: late results of a randomized trial. Am J Surg 165 (1993) 27-32
29. Terés J., Bordas J.M., Bravo D., et al. Sclerotherapy vs. distal splenorenal shunt in the elective treatment of variceal hemorrhage: a randomized controlled trial. Hepatology 7 (1987) 430-436
30. Spina G.P., Santambrogrio R., Opocher E., et al. Distal splenorenal shunt versus endoscopic sclerotherapy in the prevention of variceal rebleeding. First stage of a randomized, controlled trial. Ann Surg 211 (1990) 178-186
31. Krige J.E.J., Katze U.K., Bornman U.C., et al. Variceal recurrence, rebleeding, and survival after endoscopic injection sclerotherapy in 287 alcoholic cirrhotic patients with bleeding esophageal varices. Ann Surg 244 (2006) 764-770
32. Krige J.E., Shaw J.M., and Bornman P.C. The evolving role of endoscopic treatment of esophageal varices. Wld J Surg 29 (2005) 966-973
33. Sorbi D., Gostout C.J., Peura D., et al. An assessment of the management of acute bleeding varices: a multicenter prospective member-based study. Am J Gastroenterol 98 (2003) 2424-2434
34. Gralnek I.M., Jensen D.M., Kovacs T.O., et al. The economic impact of esophageal variceal hemorrhage: cost-effectiveness implications of endoscopic therapy. Hepatology 29 (1999) 44-50
35. Villeneuve J.-P., Pomier-Layrargues G., Duguay L., et al. Emergency portacaval shunt for variceal hemorrhage. A prospective study. Ann Surg 206 (1987) 48-52
36. Soutter D.I., Langer B., Taylor B.R., and Greig P. Emergency portosystemic shunting in cirrhotics with bleeding varices---a comparison of portacaval and mesocaval shunts. HPB Surg 1 (1989) 107-118
37. Spina G.P., Santambrogio R., Opocher E., et al. Emergency portosystemic shunt in patients with variceal bleeding. Surg Gynecol Obstet 171 (1990) 456-464
38. Borowsky S.A., Stroma S., and Lott E. Continued heavy drinking and survival in alcoholic cirrhotics. Gastroenterology 80 (1981) 1405-1409
39. Powell W.J., and Klatskin G. Duration of survival in patients with Laennec's cirrhosis. Am J Med 98 (1968) 695-716
40. Capone R.R., Buhac I., Kohberg R.C., and Balint J.A. Resistant ascites in alcoholic liver cirrhosis. Dig Dis Sci 23 (1978) 867-871
41. Grace N.D., Conn H.O., Resnick R.H., et al. Distal splenorenal versus portal systemic shunts after haemorrhage from varices: a randomized controlled trial. Hepatology 8 (1988) 1475-1481
42. Terpstra O.T., Ausema B., Bruining H.A., et al. Late results of mesocaval interposition shunting for bleeding oesophageal varices. Br J Surg 74 (1987) 787-790
43. Smith R.B., Warren W.D., Salam A.A., et al. Dacron interposition shunts for portal hypertension. An analysis of morbidity correlates. Ann Surg 192 (1980) 9-17
44. Fletcher M.S., Dawson J.L., and Williams R. Long term follow-up of interposition mesocaval shunting in portal hypertension. Br J Surg 68 (1981) 485-487
45. Helton W.S., Belshaw A., Althaus S., et al. Critical appraisal of the angiographic portacaval shunt (TIPS). Am J Surg 165 (1993) 566-571
46. LaBerge J.M. Transjugular intrahepatic portosystemic shunt--role in treating intractable variceal bleeding, ascites, and hepatic hydrothorax. Clin Liver Dis 10 (2006) 583-598
47. Bayer T.D., and Haskal Z.J. The role of transjugular intrahepatic shunt in the management of portal hypertension. Hepatology 41 (2005) 386-400
48. Sanyal A.J., Freedman A.M., Shiftman M.L., et al. Portosystemic encephalopathy after transjugular intrahepatic portosystemic shunt: results of a prospective controlled study. Hepatology 20 (1994) 46-55
49. Rössle M., Haag K., Ochs A., et al. The transjugular intrahepatic portosystemic stent-shunt procedure for variceal bleeding. N Engl J Med 330 (1994) 165-171
50. Jalan R., Elton R.A., Redhead D.N., et al. Analysis of prognostic variables in the prediction of mortality, shunt failure, variceal rebleeding and encephalopathy following the transjugular intrahepatic portosystemic stent-shunt for variceal haemorrhage. J Hepatol 23 (1995) 123-128
51. Garcia Jr. N., and Sanyal A.J. Portal hypertension. Clin Liver Dis 5 (2001) 1-26
52. Klempnauer J., and Schrem H. Review: surgical shunts and encephalopathy. Metabolic Brain Dis 16 (2001) 21-25