The protective effects of a fermented substance from Saccharomyces cerevisiae on carbon tetrachloride-induced liver damage in rats

Clinical Nutrition

Volumn 28, Issue 3, 2009, Pages 338-345

  Lai, Jinn Tsyy ^a   Hsieh, Wen Tsong ^b   Fang, Hsun Lang ^b   Lin, Wen Chuan ^b  

^a FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

carbon tetrachloride; liver fibrosis; Saccharomyces cerevisiae

Indexed keywords

AMINOTRANSFERASE; CARBON TETRACHLORIDE; COLLAGEN; HYDROXYPROLINE; MALONALDEHYDE; METHIONINE ADENOSYLTRANSFERASE; SERUM ALBUMIN; TRANSFORMING GROWTH FACTOR BETA1;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FATTY LIVER; FEEDING; FERMENTED PRODUCT; LIVER FIBROSIS; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; LIVER WEIGHT; MALE; NONHUMAN; PROTEIN EXPRESSION; RANDOMIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SACCHAROMYCES CEREVISIAE; SPLEEN WEIGHT; TISSUE SECTION;

ANIMALS; CARBON TETRACHLORIDE; COLLAGEN TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; FERMENTATION; HYDROXYPROLINE; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; MALONDIALDEHYDE; METHIONINE ADENOSYLTRANSFERASE; ORGAN SIZE; RANDOM ALLOCATION; RATS; RATS, WISTAR; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SERUM ALBUMIN; TRANSAMINASES; TRANSFORMING GROWTH FACTOR BETA1;

EID: 67349215135     PISSN: 02615614     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clnu.2009.01.011     Document Type: Article

References (34)

1. Wu G., Fang Y.Z., Yang S., Lupton J.R., and Turner N.D. Glutathione metabolism and its implications for health. J Nutr 134 (2004) 489-492
2. Czeczot H., Scibior D., Skrzycki M., and Podsiad M. Glutathione and GSH-dependent enzymes in patients with liver cirrhosis and hepatocellular carcinoma. Acta Biochim Pol 53 (2006) 237-242
3. Loguercio C., Nardi G., Prota G., Del Vecchio Blanco C., and Coltorti M. Decrease of total, glutathione and cysteine SH in non-alcoholic cirrhosis. Ital J Gastroenterol 22 (1990) 13-15
4. Matsui H., Ikeda K., Nakajima Y., Horikawa S., Yukihiro I., and Kawada N. Sulfur-containing amino acids attenuate the development of liver fibrosis in rats through down-regulation of stellate cell activation. J Hepatol 40 (2004) 917-925
5. Arosio B., Santambrogio D., Gagliano N., Ryan A., Biasi F., Vergani C., et al. Glutathione pretreatment lessens the acute liver injury induced by carbon tetrachloride. Pharmacol Toxicol 81 (1997) 164-168
6. Nishida K., Ohta Y., and Ishiguro I. Preventive effect of γ-glutamylcysteinylethyl ester on carbon tetrachloride-induced hepatic triglyceride accumulation in mice. Toxicol Lett 95 (1998) 141-146
7. Gebhardt R. Oxidative stress, plant-derived antioxidant and liver fibrosis. Planta Med 68 (2002) 289-296
8. Loguercio C., De girolamo V., Federico A., Feng S.L., Crafa E., Cataldi V., et al. Relationship of blood trace elements to liver damage, nutritional status, and oxidative stress in chronic nonalcoholic liver disease. Biol Trace Elem Res 81 (2001) 245-254
9. Ferre N., Girona J., Cabre M., Joven J., LaVille A., Masana L., et al. Hepatic production of apolar aldehydes in rats with carbon tetrachloride-induced cirrhosis. Mol Cell Biochem 198 (1999) 57-60
10. He Y.T., Liu D.W., Ding L.Y., Li Q., and Xiao Y.H. Therapeutic effects and molecular mechanisms of anti-fibrosis herbs and selenium on rats with hepatic fibrosis. World J Gastroenterol 10 (2004) 703-706
11. Li Y., Wei G., and Chen J. Glutathione: a review on biotechnological production. Appl Microbiol Biotechnol 66 (2004) 233-242
12. Grant C.M., Maclver F.H., and Dawes I.W. Glutathione synthase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide gamma-glutamylcysteine. Mol Biol Cell 8 (1997) 1699-1707
13. Kim H.S., and Fay J.C. Genetic variation in the cysteine biosynthesis pathway causes sensitivity to pharmacological compounds. Proc Natl Acad Sci U S A 104 (2007) 19387-19391
14. Santiago L.A., and Mori A. Antioxidant defenses of baker's yeast against free radicals and lipid peroxides in rat brain. Arch Biochem Biophys 306 (1993) 16-21
15. Eide D.J. Multiple regulatory mechanisms maintain zinc homeostasis in Saccharomyces cerevisiae. J Nutr 133 5 Suppl. 1 (2003) 1532S-1535S
16. Agbor G.A., Vinson J.A., Patel S., Patel K., Scarpati J., Shiner D., et al. Effect of selenium- and glutathione-enriched yeast supplementation on a combined atherosclerosis and diabetes hamster model. J Agric Food Chem 55 (2007) 8731-8736
17. Lai JT, Fang HL, Lin WL, Lin WC. Protective effect of a fermented substance from Saccharomyces cerevisiae on liver injury in mice caused by acetaminophen. Biosci Biotechnol Biochem 2008;72:2514-20.
18. Robak J., and Gryglewski R.J. Flavonoids are scavengers of superoxide anions. Biochem Pharmacol 37 (1998) 837-841
19. Ohkawa H., Ohishi N., and Yagi K. Assay for lipid peroxide in animal tissue by thiobarbituric acid reaction. Anal Biochem 95 (1979) 351-358
20. Lowry O.H., Rosebrough N.J., Farrm A.L., and Randallm R.J. Protein measurement with the Folin phenol reagent. J Biol Chem 193 (1951) 265-275
21. Hssin P.L., and Hilf R. A fluorometric method for determination of oxidized and reduced glutathione in tissue. Anal Biochem 74 (1976) 214-226
22. Neuman R.E., and Logan M.A. The determination of hydroxyproline. J Biol Chem 184 (1950) 299-306
23. Aebi H. Catalase in vitro. Methods Enzymol 105 (1984) 121-126
24. Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162 (1987) 156-159
25. Mato J.S., Corrales F.J., Lu S.C., and Avila M.A. S-adenosylmethionine: a control switch that regulates liver function. FASEB J 16 (2002) 15-26
26. Lin W.C., and Lin W.L. Ameliorative effect of Ganoderma lucidum on carbon tetrachloride-induced liver fibrosis in rats. World J Gastroenterol 14 (2006) 265-270
27. Gill M.A., and Kircbain W.R. Alcoholic liver disease. In: Dipiro J.T., Talbert R.L., Yee G.C., Matzke G.R., Wells B.G., and Poser L.M. (Eds). Pharmacotherapy: a pathophysiologic approach (1997), Appleton & Lange, Stamford 785-800
28. Hanauske-Abel H.M. Fibrosis: of the liver, representative molecular elements and their emerging role as anti-fibrotic targets. In: Zakim D., and Boyer T.D. (Eds). Hepatology: a textbook of liver disease (2003), WB Saunders, Philadelphia 347-394
29. Pierce R.A., Glaugm M.R., Grecom R.S., Mackenzie J.W., Boyd C.D., and Deak S.B. Increased procollagen mRNA levels in carbon tetrachloride-induced liver fibrosis in rats. J Biol Chem 262 (1987) 1652-1658
30. Gressner A.M., and Weiskirchen R. Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-β as major players and therapeutic targets. J cell Mol Med 10 (2006) 76-99
31. Vina J., Perez C., Kurukawa T., Palacin M., and Vina J.R. Effect of oral glutathione on hepatic glutathione levels in rats and mice. Br J Nutr 62 (1989) 383-391
32. 2-isoprostanes stimulate collagen synthesis in activated hepatic stellate cells: a link with liver fibrosis?. Lab Invest 85 (2005) 1381-1391
33. Xu D.H., Mei X.T., Chen Y., Li Y.M., Lv J.Y., and Xu S.B. Protective effects of 5,4′-dihydroxy-3′-5′-dimethoxy-7-O-beta-D-glucopyranosyloxy-flavone on experimental hepatic injury. World J Gastroenterol 38 (2005) 1764-1768
34. Nadkarni G.D., and D'Souza N.B. Hepatic antioxidant enzymes and lipid peroxidation in carbon tetrachloride-induced liver cirrhosis. Biochem Med Biol 40 (1998) 42-45