The role of developmental toxicity studies in acute exposure assessments: Analysis of single-day vs. multiple-day exposure regimens

Regulatory Toxicology and Pharmacology

Volumn 54, Issue 2, 2009, Pages 134-142

  Davis, Allen ^a,b   Gift, Jeff S ^b   Woodall, George M ^b   Narotsky, Michael G ^c   Foureman, Gary L ^b  

^a OAK RIDGE INSTITUTE FOR SCIENCE AND EDUCATION   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Acute exposure; Benchmark dose; Butylbenzyl phthalate; Developmental toxicity; Multiple day; Risk assessment; Single day; Tributyltin

Indexed keywords

PHTHALIC ACID BENZYL BUTYL ESTER; TRIBUTYLTIN;

ACUTE TOXICITY; ARTICLE; CONCENTRATION RESPONSE; EMBRYOTOXICITY; FETOTOXICITY; GESTATIONAL AGE; HALF LIFE TIME; LETHALITY; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; RISK ASSESSMENT; TOXICITY TESTING;

ACUTE TOXICITY TESTS; ANIMALS; BENCHMARKING; CONGENITAL ABNORMALITIES; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO LOSS; EMBRYONIC DEVELOPMENT; ENDPOINT DETERMINATION; ENVIRONMENTAL POLLUTANTS; FEMALE; FETAL DEVELOPMENT; GESTATIONAL AGE; MATERNAL EXPOSURE; MODELS, BIOLOGICAL; MODELS, STATISTICAL; PHTHALIC ACIDS; PREGNANCY; RISK ASSESSMENT; TOXICITY TESTS, CHRONIC; TRIALKYLTIN COMPOUNDS;

EID: 67349188880     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2009.03.006     Document Type: Article

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