Transdermal delivery of tolterodine by O-acylmenthol: In vitro/in vivo correlation

International Journal of Pharmaceutics

Volumn 374, Issue 1-2, 2009, Pages 73-81

  Zhao, Ligang ^a   Li, Yan ^a   Fang, Liang ^a   He, Zhonggui ^a   Liu, Xuntao ^a   Wang, Lin ^a   Xu, Yongnan ^a   Ren, Changshu ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

In vitro studies; In vivo studies; O Acylmenthol; Tolterodine; Transdermal delivery

Indexed keywords

2 ISOPROPYL 5 METHYLCYCLOHEXYL 2 HYDROXYPANOATE; 2 ISOPROPYL 5 METHYLCYCLOHEXYLHEPTANOATE; 2 ISOPROPYL 5 METHYLCYCLOHEXYLOCTADEC 9 ENOATE; 2 ISOPROPYL 5 METHYLCYCLOHEXYLTETRADECANOATE; ACRYLIC ACID DERIVATIVE; ADHESIVE AGENT; DT 2677; DT 2852; DT 4098; DT 9301; LEVO MENTHOL; MYRISTIC ACID ISOPROPYL ESTER; O ACYLMENTHOL DERIVATIVE; PENETRATION ENHANCING AGENT; TOLTERODINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DIFFUSION; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG SOLUBILITY; HYDROPHILICITY; LIPOPHILICITY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN PERMEABILITY; STEADY STATE; TIME TO MAXIMUM PLASMA CONCENTRATION; TRANSDERMAL PATCH; VISCOSITY;

ADMINISTRATION, CUTANEOUS; ANIMALS; BENZHYDRYL COMPOUNDS; CHEMISTRY, PHARMACEUTICAL; CRESOLS; DIFFUSION CHAMBERS, CULTURE; EXCIPIENTS; MALE; MENTHOL; MUSCARINIC ANTAGONISTS; MYRISTATES; PERMEABILITY; PHENYLPROPANOLAMINE; RATS; RATS, WISTAR; SKIN ABSORPTION;

EID: 67349187403     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.03.005     Document Type: Article

References (35)

1. Abrams P., Freeman R., Anderstrom C., and Mattiasson A. Tolterodine, a new antimuscarinic agent: as effective but better tolerated than oxybutynin in patients with an overactive bladder. Br. J. Urol. 81 (1998) 801-810
2. Auclair F., Besnard M., Dupont C., and Wepierre J. Importance of blood flow to the local distribution of drugs after percutaneous absorption in the bipediculated dorsal flap of the hairless rat. Skin Pharmacol. 4 (1991) 1-8
3. Bronaugh R.L., and Collier S.W. Protocol for in vitro percutaneous absorption studies. In: Bronaugh R.L., and Maibach H.I. (Eds). In Vitro Percutaneous Absorption: Principles, Fundamentals, and Applications (1991), CRC Press, Boston 237-241
4. Cheong H.-A., and Choi H.-K. Effect of ethanolamine salts and enhancers on the percutaneous absorption of piroxicam from a pressure sensitive adhesive matrix. Eur. J. Pharm. Sci. 18 (2003) 149-153
5. Cho Y.-J., and Choi H.-K. Enhancement of percutaneous absorption of ketoprofen: effect of vehicles and adhesive matrix. Int. J. Pharm. 169 (1998) 95-104
6. Fang L., Kobayashi Y., Numajiri S., Kobayashi D., Sugibayashi K., and Morimoto Y. The enhancing effect of a triethanolamine-ethanol-isopropyl myristate mixed system on the skin permeation of acidic drugs. Biol. Pharm. Bull. 25 (2002) 1339-1344
7. Fang L., Numajiri S., Kobayashi D., and Morimoto Y. The use of complexation with alkanolamines to facilitate skin permeation of mefenamic acid. Int. J. Pharm. 262 (2003) 13-22
8. Golden G.M., Mckie J.E., and Potts R.O. Role of stratum corneum lipid fluidity in transdermal drug flux. J. Pharm. Sci. 76 (1987) 25-28
9. Guy R.H., and Hadgraft J. Rate control in transdermal delivery. Int. J. Pharm. 82 (1992) R1-R6
10. Guyot M., and Fawaz F. Design and in vitro evaluation of adhesive matrix for transdermal delivery of propranolol. Int. J. Pharm. 204 (2000) 171-182
11. Hadgraft J. Passive enhancement strategies in topical and transdermal drug delivery. Int. J. Pharm. 184 (1999) 1-6
12. Hai N.-T., Kim J., Park E.S., and Chi S.-C. Formulation and biopharmaceutical evaluation of transdermal patch containing benztropine. Int. J. Pharm. 357 (2008) 55-60
13. Hood H.L., Kraeling M.E., Robl M.G., and Bronaugh R.L. The effects of an alpha hydroxy acid (glycolic acid) on hairless guinea pig skin permeability. Food Chem. Toxicol. 37 (1999) 1105-1111
14. Hrabálek A., Doležal P., Vávrová K., Zbytovská J., Holas T., Klimentová J., and Novotný J. Synthesis and enhancing effect of transkarbam 12 on the transdermal delivery of theophylline, clotrimazole, flobufen, and griseofulvin. Pharm. Res. 23 (2006) 912-919
15. Hui X., Wester R.C., Zhai H., and Maibach H.I. Chemical partitioning into powdered human stratum corneum: a useful in vitro model for studying interaction of chemicals and human skin. In: Bronaugh R.L., and Maichach H.I. (Eds). Percutaneous Absorption (2005), Taylor & Francis, Boca Raton 291-302
16. Kang J.-H., Lee J.-H., Park Y.-J., Kim K.-S., and Lee J.-Y. An efficient synthesis of racemic tolterodine. Bull. Korean Chem. Soc. 29 (2008) 519-520
17. Kemppainen B.W., Reifenrath W.G., Stafford R.G., and Mehta M. Methods for in vitro skin absorption studies of a lipophilic toxin produced by red tide. Toxicology 66 (1991) 1-17
18. Kim J.-H., Cho Y.-J., and Choi H.-K. Effect of vehicles and pressure sensitive adhesives on the permeation of tacrine across hairless mouse skin. Int. J. Pharm. 196 (2000) 105-113
19. Kiptoo P.K., Hamad M.O., Crooks P.A., and Stinchcomb A.L. Enhancement of transdermal delivery of 6-β-naltrexol via a codruglinked to hydroxybupropion. J. Control. Release 113 (2006) 137-145
20. Kubota K., and Maibach H.I. Significance of viable skin layers in percutaneous absorption and its implication in mathematical models: theoretical consideration based on parameters for betamethasone 17-valerate. J. Pharm. Sci. 83 (1994) 1300-1306
21. Lee P.J., Ahmad N., Langer R., Mitragotri S., and Shastri V.P. Evaluation of chemical enhancers in the transdermal delivery of lidocaine. Int. J. Pharm. 308 (2006) 33-39
22. Leichtnam M.L., Rolland H., Wüthrich P., and Guy R.H. Identification of penetration enhancers for testosterone transdermal delivery from spray formulations. J. Control. Release 113 (2006) 57-62
23. Montagna W. Histology and cytochemistry of human skin. IX. The distribution of non-specific esterases. J. Biophys. Biochem. Cytol. 1 (1955) 13-16
24. Narishetty S.T.K., and Panchagnula R. Transdermal delivery of zidovudine: effect of terpenes and their mechanism of action. J. Control. Release 95 (2004) 367-379
25. Nash R.A., Mehta D.B., Matias J.R., and Orentreich N. The possibility of lidocaine ion pair absorption through excised hair-less mouse skin. Skin Pharmacol. 5 (1992) 160-170
26. Shargel L., and Yu A.B.C. Multicompartment models. In: Shargel L., and Yu A.B.C. (Eds). Applied Biopharmaceutics and Pharmacokinetics (1985), Appleton & Lange, Norwalk, CT 51-56
27. Tan H.S., and Pfister W.R. Pressure-sensitive adhesives for transdermal drug delivery systems. Pharm. Sci. Technol. Today 2 (1999) 60-69
28. Uchida T., Lee C.K., Sekiya N., and Goto S. Enhancement effect an ethanol/panasate 800 binary vehicle on anti-inflammatory drug permeation across excised hairless mouse skin. Biol. Pharm. Bull. 16 (1993) 168-171
29. Valiverti S., Hammell D.C., Paudel I.S., Hamad M.O., Crooks P.A., and Stinchcomb A.L. In vivo evaluation of 3-alkyl ester transdermal prodrugs of naltrexone in hairless guinea pigs. J. Control. Release 102 (2005) 509-520
30. Vávrová K., Hrabálek A., Doležal P., Holas T., and Klimentová J. Biodegradable derivatives of tranexamic acid as transdermal permeation enhancers. J. Control. Release 104 (2005) 41-49
31. Wefer J., Truss M.C., and Jonas U. Tolterodine: an overview. World J. Urol. 19 (2001) 312-318
32. Yamashita F., Bando M., Koyama Y., Kitagawa S.M., Takakura Y., and Hashida M. In vitro and in vivo analysis of skin penetration enhancement based on a two-layer diffusion model with polar and nonpolar routes in the stratum corneum. Pharm. Res. 11 (1994) 185-191
33. Yamashita F., Koyama Y., Kitano M., Takakura Y., and Hashida M. Analysis of in vivo skin penetration enhancement by oleic acid based on a two-layer diffusion model with polar and nonpolar routes in the stratum corneum. Int. J. Pharm. 117 (1995) 173-179
34. Zhao L., Fang L., Xu Y., Liu S., He Z., and Zhao Y. Effect of O-acylmenthol on transdermal delivery of drugs with different lipophilicity. Int. J. Pharm. 352 (2008) 92-103
35. Zhao L., Fang L., Xu Y., Zhao Y., and He Z. Transdermal delivery of penetrants with differing lipophilicities using O-acylmenthol derivatives as penetration enhancers. Eur. J. Pharm. Biopharm. 69 (2008) 199-213