Biodegradable derivatives of tranexamic acid as transdermal permeation enhancers

Journal of Controlled Release

Volumn 104, Issue 1, 2005, Pages 41-49

  Vávrová, Kateřina ^a   Hrabálek, Alexandr ^a   Doležal, Pavel ^a   Holas, Tomáš ^a   Klimentová, Jana ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

Enzymatic degradability; Permeation enhancer; Tranexamic acid derivatives; Transdermal

Indexed keywords

BIODEGRADATION; BIOSYNTHESIS; DERIVATIVES; DRUG PRODUCTS; ENZYMES; ESTERS; HYDROPHILICITY; KETONES; METABOLITES; SUSPENSIONS (FLUIDS);

ENHANCEMENT RATIO (ER); TRANEXAMIC ACID (TXA); TRANSDERMAL DELIVERY; TRANSDERMAL PERMEATION;

SKIN;

CARBAMIC ACID; ESTER DERIVATIVE; ESTERASE; LAUROCAPRAM; MYRISTIC ACID ISOPROPYL ESTER; THEOPHYLLINE; TRANEXAMIC ACID;

ACIDITY; AQUEOUS SOLUTION; ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; DISPERSION; DRUG DEGRADATION; DRUG DESIGN; DRUG PENETRATION; DRUG RELEASE; DRUG SYNTHESIS; ENZYME MECHANISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMEOSTASIS; HUMAN; HUMAN TISSUE; HYDROLYSIS; HYDROPHILICITY; IN VITRO STUDY; INFRARED SPECTROSCOPY; LIPOPHILICITY; PRIORITY JOURNAL; SKIN PERMEABILITY; THIN LAYER CHROMATOGRAPHY;

EID: 18144384750     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.01.002     Document Type: Article

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