Immunohistochemical characterization of the extracellular matrix in normal mitral valves and in chronic valve disease (endocardiosis) in dogs

Research in Veterinary Science

Volumn 87, Issue 2, 2009, Pages 277-283

  Aupperle, Heike ^a   März, Imke ^a   Thielebein, Jens ^b   Kiefer, Birgit ^b   Kappe, Alexander ^a   Schoon, Heinz Adolf ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Chronic valve disease; Dog; Endocardiosis; Extracellular matrix; Immunohistochemistry; Mitral valve

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; COLLAGEN TYPE 5; COLLAGEN TYPE 6; ELASTIN; FIBRONECTIN; HEPARAN SULFATE; LAMININ; PROTEOGLYCAN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOG DISEASE; EXTRACELLULAR MATRIX; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MITRAL VALVE DISEASE; MYXOMATOSIS; NONHUMAN;

ANIMALS; CELL DIVISION; COLLAGEN; DOG DISEASES; DOGS; ENDOCARDITIS; EXTRACELLULAR MATRIX; HEART VALVE DISEASES; HEART VALVES; IMMUNOHISTOCHEMISTRY; MITRAL VALVE; PROTEOGLYCANS; REFERENCE VALUES; SPECIES SPECIFICITY;

CANIS FAMILIARIS;

EID: 67349184928     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2009.01.009     Document Type: Article

References (36)

1. Akhtar S., Meek K.M., and James V. Immunolocalization of elastin, collagen type I and type III, fibronectin, and vitronectin in extracellular matrix components of normal and myxomatous mitral heart valve chordae tendineae. Cardiovascular Pathology 8 (1999) 203-211
2. Baade S., Aupperle H., Grevel V., and Schoon H.-A. Histopathological and immunohistochemical investigations of hepatic lesions associated with congenital portosystemic shunt in dogs. Journal of Comparative Pathology 134 (2006) 84-94
3. Barber J.E., Kurtis F.K., Ratliff N.B., Cosgrove D.M., Griffin B.P., and Vesely I. Mechanical properties of myxomatous mitral valves. Surgery for Acquired Cardiovascular Disease 122 (2001) 955-962
4. Barth P.J., Köster H., and Moosdorf R. CD34+ fibrocytes in normal mitral valves and myxomatous mitral valve degeneration. Pathological Research in Practice 201 (2005) 301-304
5. Bashey R., Martinez-Hernandez A., and Jimenez S.A. Isolation, characterization, and localization of cardiac collagen VI. Circulation Research 70 (1992) 1006-1017
6. Black A., French A.T., Dukes-McEwan J., and Corcoran B.M. Ultrastructural morphologic evaluation of the phenotype of valvular interstitial cells in dogs with myxomatous degeneration of the mitral valve. American Journal of Veterinary Research 66 (2005) 1408-1414
7. Boudoulas H., Kolibash A.J., Baker P., King B.D., and Wooley C.F. Mitral prolapse syndrome and the mitral valve prolapse syndrome: a diagnostic classification and pathogenesis of symptoms. American Heart Journal 118 (1989) 797-818
8. Buchanan J.W. Chronic valvular disease (endocardiosis) in dogs. Advances in Veterinary Science of Comparative Medicine 21 (1977) 75-108
9. Cole W.G., Chan D., Hickey A.J., and Wilcken D.E.L. Collagen composition of normal and myxomatous human mitral valves. Biochemistry Journal J 219 (1984) 451-460
10. Corcoran B.M., Black A., McEwan J., French A., Smith P., and Devine C. Identification of surface morphologic changes in the mitral valve leaflets and chordae tendineae of dogs with myxomatous degeneration. American Journal of Veterinary Research 65 (2004) 198-206
11. Dreger S., Taylor P.M., Allen S.P., and Youb M.H. Profile and localization of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in human heart valves. Journal of Heart Valve Disease 11 (2002) 875-880
12. Ernst E., Schneider P., and Trautwein G. Die Endokardiose der Artioventrikularklappen des Hundes IV Elektronenmikroskopische Untersuchungen. Zentralblatt Veterinär Medizin A 21 (1974) 400-416
13. Farquharson C., and Robins S.P. Immunolocalization of collagen types I, III and IV, elastin and fibronectin within the heart of normal and copper-deficient rats. Journal of Comparative Pathology 104 (1991) 245-255
14. Fondard O., Detaint D., Jung B., Chouquex C., Adle-Biassette H., Jarraya M., Hvass U., Couetil J.-P., Henin D., Michel J.-B., Vahanian A., and Jacob M.-P. Extracellular matrix remodelling in human aortic valve disease: the role of matrix metalloproteinases and their tissue inhibitors. European Heart Journal 26 (2005) 1333-1341
15. Grüninger B., Schoon H.-A., Schoon D., Menger S., and Klug E. Incidence and morphology of endometrial angiopathies in mares with relationship to age and parity. Journal of Comparative Pathology 119 (1998) 293-309
16. Häggström J., Pedersen H.D., and Kvart C. New insights into degenerative mitral valve disease in dogs. Veterinary Clinics of Small Animals 34 (2004) 1209-1226
17. Kersten U., and Brass W. Untersuchungen zur Ätiologie und Pathogenese der Endokardiose und Endokarditis des Hundes. Teil 1: Einleitung und klinische Befunde. Deutsche Tierärztliche Wochenschrift 80 (1973) 299-301
18. Kitten G.T., Kolker S.J., Krob S.L., and Klewer S.E. Type VI collagen in the cardiac valves and connective tissue septa during heart development. Brazilian Journal of Medical and Biological Research 29 (1996) 1189-1193
19. Kogure K. Pathology of chronic mitral valvular disease in the dog. Japanese Journal of Veterinary Science 42 (1980) 323-325
20. Latif N., Sarathchandra P., Taylor P.M., Antoniw J., and Yacoub M.H. Localization and pattern of expression of extracellular matrix components in human heart valves. Journal of Heart Valve Disease 14 (2005) 218-227
21. Mollnau H., Münkel B., and Schaper J. Collagen VI in the extracellular matrix of normal and failing human myocardium. Herz 20 (1995) 89-94
22. Mow T., and Pedersen H.D. Increased endothelin-receptor density in myxomatous canine mitral valve leaflets. Journal of Cardiovascular Pathology 34 (1999) 254-260
23. Nasuti J.F., Zhang P.J., Feldman M.D., Pasha T., Kuhrana J.S., Gorman III J.H., Gorman R.C., Narula J., and Narula N. Fibrillin and other matrix proteins in mitral valve prolapse syndrome. Annals of Thoracic Surgery 77 (2004) 532-536
24. Olsen L.H., Mortensen K., Martinussen T., Larsson L.-I., Baandrup U., and Pedersen H.D. Increased NADPH-diaphorase activity in canine myxomatous mitral valve leaflets. Journal of Comparative Pathology 129 (2003) 120-130
25. Oyama M.A., and Chittur S.V. Genomic expression patterns of mitral valve tissue from dogs with degenerative mitral valve disease. American Journal of Veterinary Research 67 (2006) 1307-1318
26. Pedersen H.D., and Häggström J. Mitral valve prolapse in the dog: a model of mitral valve prolapse in man. Cardiovascular Research 47 (2000) 234-243
27. Rabkin E., Aikawa M., Stone J.R., Fukumoto Y., Libby P., and Schoen F.J. Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodelling in myxomatous heart valves. Circulation 104 (2001) 2525-2532
28. Robinson W.F., and Maxie M.G. Endocardiosis in dogs. In: Jubb K.V.F., Kennedy P.C., and Palmer N. (Eds). Pathology of Domestic Animals. fourth ed. vol. 3 (1993), Academic Press, San Diego, New York, Boston, London, Sydney, Tokyo, Toronto 23-24
29. Schneider P., Ernst E., and Trautwein G. Enzymchemie der Atrioventrikularklappen bei der Endokardiose des Hundes. Veterinary Pathology 10 (1973) 281-294
30. Schole J., Sallmann H.-P., Brass W., Kersten U., Schütt I., Delbrück A., Trautwein G., Messow C., Amtsberg G., Kirchhoff H., Döhler K.D., and Rapp K.G. Experimentelle Untersuchungen zum Bindegewebsstoffwechsel des Hundes bei unterschiedlichen Haltungs- und Fütterungsbedingungen, unter besonderer Berücksichtigung der Endokardiose. Zentralblatt der Veterinär Medizin Reihe A 29 (1982) 253-270
31. Sekiguchi K., Hakomori S., Funahashi M., Matsumoto I., and Seno N. Binding of fibronectin and its proteolytic fragments to glycosaminoglycans. Journal of Biology and Chemistry 258 (1983) 14359-14365
32. Talts J.F., Andac Z., Gohring W., Branaccio A., and Timpl R. Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins. European Molecular Biology Organization Journal 18 (1999) 863-870
33. Tamura K., Fukuda Y., Ishizaki M., Masuda Y., Yamanaka N., and Ferrans F.J. Abnormalities in elastic fibres and other connective-tissue components of floppy mitral valve. American Heart Journal 129 (1995) 1149-1158
34. Taylor P.M., Batten P., Brand N.J., Thomas P.S., and Yacoub M.H. The cardiac valve interstitial cell. International Journal of Biochemistry and Cell Biology 35 (2003) 113-118
35. Trueb B., Schreier T., Bruckner P., and Winterhalter K.H. Type VI collagen represents a major fraction of connective tissue collagens. European Journal Biochemistry 166 (1987) 699-703
36. Whitney J.C. Cardiovascular pathology. Journal of Small Animal Practice 8 (1967) 459-465