-
1
-
-
0033570912
-
The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression
-
Barradas M, Monjas A, Diaz-Meco MT, Serrano M, Moscat J. 1999. The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression. EMBO J 18:6362-6369.
-
(1999)
EMBO J
, vol.18
, pp. 6362-6369
-
-
Barradas, M.1
Monjas, A.2
Diaz-Meco, M.T.3
Serrano, M.4
Moscat, J.5
-
2
-
-
0035022291
-
-
Boehrer S, Chow KU, Puccetti E, Ruthardt M, Godzisard S, Krapohl A, Schneider B, Hoelzer D, Mitrou PS, Rangnekar VM, Weidmann E. 2001. Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia. 2:103-107.
-
(2001)
Deregulated Expression of Prostate Apoptosis Response Gene-4 in Less Differentiated Lymphocytes and Inverse Expressional Patterns of Par-4 and Bcl-2 in Acute Lymphocytic Leukemia
, vol.2
, pp. 103-107
-
-
Boehrer, S.1
Chow, K.U.2
Puccetti, E.3
Ruthardt, M.4
Godzisard, S.5
Krapohl, A.6
Schneider, B.7
Hoelzer, D.8
Mitrou, P.S.9
Rangnekar, V.M.10
Weidmann, E.11
-
3
-
-
0037086078
-
In lymphatic cells par-4 sensitizes to apoptosis by down-regulating bcl-2 and promoting disruption of mitochondrial membrane potential and caspase activation
-
Boehrer S, Chow KU, Beske F, Kukoc-Zivojnov N, Puccetti E, Ruthardt M, Baum C, Rangnekar VM, Hoelzer D, Mitrou PS, Weidmann E. 2002. In lymphatic cells par-4 sensitizes to apoptosis by down-regulating bcl-2 and promoting disruption of mitochondrial membrane potential and caspase activation. Cancer Res 62:1768-1775.
-
(2002)
Cancer Res
, vol.62
, pp. 1768-1775
-
-
Boehrer, S.1
Chow, K.U.2
Beske, F.3
Kukoc-Zivojnov, N.4
Puccetti, E.5
Ruthardt, M.6
Baum, C.7
Rangnekar, V.M.8
Hoelzer, D.9
Mitrou, P.S.10
Weidmann, E.11
-
4
-
-
0030824809
-
Immunohistochemical analysis of the proapoptotic protein Par-4 in normal rat tissues
-
Boghaert ER, Sells SF, Walid AJ, Malone P, Williams NM, Weinstein MH, Strange R, Rangnekar VM. 1997. Immunohistochemical analysis of the proapoptotic protein Par-4 in normal rat tissues. Cell Growth Differ 8:881-890.
-
(1997)
Cell Growth Differ
, vol.8
, pp. 881-890
-
-
Boghaert, E.R.1
Sells, S.F.2
Walid, A.J.3
Malone, P.4
Williams, N.M.5
Weinstein, M.H.6
Strange, R.7
Rangnekar, V.M.8
-
5
-
-
0032851963
-
Implications of cell death regulation in the pathogenesis and treatment of prostate cancer
-
Bruckheimer EM, Gjertsen BT, McDonnell TJ. 1999. Implications of cell death regulation in the pathogenesis and treatment of prostate cancer. Semin Oncol 26:382-398.
-
(1999)
Semin Oncol
, vol.26
, pp. 382-398
-
-
Bruckheimer, E.M.1
Gjertsen, B.T.2
McDonnell, T.J.3
-
6
-
-
0035477544
-
Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression
-
Chakraborty M, Qiu SG, Vasudevan KM, Rangnekar VM. 2001. Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression. Cancer Res 61:7255-7263.
-
(2001)
Cancer Res
, vol.61
, pp. 7255-7263
-
-
Chakraborty, M.1
Qiu, S.G.2
Vasudevan, K.M.3
Rangnekar, V.M.4
-
7
-
-
0037005888
-
P62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibition
-
Chang S, Kim JH, Shin J. 2002. P62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibition. FEBS Lett 510:57-61.
-
(2002)
FEBS Lett
, vol.510
, pp. 57-61
-
-
Chang, S.1
Kim, J.H.2
Shin, J.3
-
8
-
-
0038504065
-
Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter
-
Cheema SK, Mishra SK, Rangnekar VM, Tari AM, Kumar R, Lopez-Berestein G. 2003. Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter. J Biol Chem 278:19995-20005.
-
(2003)
J Biol Chem
, vol.278
, pp. 19995-20005
-
-
Cheema, S.K.1
Mishra, S.K.2
Rangnekar, V.M.3
Tari, A.M.4
Kumar, R.5
Lopez-Berestein, G.6
-
9
-
-
0033521923
-
Decreased expression of the proapoptotic protein Par-4 in renal cell carcinoma
-
Cook J, Krishnan S, Ananth S, Sells SF, Shi Y, Walther MM, Linehan WM, Sukhatme VP, Weinstein MH, Rangnekar VM. 1999. Decreased expression of the proapoptotic protein Par-4 in renal cell carcinoma. Oncogene 18:1205-1208.
-
(1999)
Oncogene
, vol.18
, pp. 1205-1208
-
-
Cook, J.1
Krishnan, S.2
Ananth, S.3
Sells, S.F.4
Shi, Y.5
Walther, M.M.6
Linehan, W.M.7
Sukhatme, V.P.8
Weinstein, M.H.9
Rangnekar, V.M.10
-
10
-
-
0034131261
-
Consistent and fast inhibition of colon carcinogenesis by polyethylene glycol in mice and rats given various carcinogens
-
Corpet DE, Parnaud G, Delverdier M, Peiffer G, Tache S. 2000. Consistent and fast inhibition of colon carcinogenesis by polyethylene glycol in mice and rats given various carcinogens. Cancer Res 60:3160-3164.
-
(2000)
Cancer Res
, vol.60
, pp. 3160-3164
-
-
Corpet, D.E.1
Parnaud, G.2
Delverdier, M.3
Peiffer, G.4
Tache, S.5
-
11
-
-
0035895077
-
Role of protein kinase C zeta isoform in Fas resistance of immature myeloid KG1a leukemic cells
-
de Thonel A, Bettaieb A, Jean C, Laurent G, Quillet-Mary A. 2001. Role of protein kinase C zeta isoform in Fas resistance of immature myeloid KG1a leukemic cells. Blood 98:3770-3777.
-
(2001)
Blood
, vol.98
, pp. 3770-3777
-
-
Thonel, A.1
Bettaieb, A.2
Jean, C.3
Laurent, G.4
Quillet-Mary, A.5
-
12
-
-
0030572696
-
The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C
-
Diaz-Meco MT, Municio MM, Frutos S, Sanchez P, Lozano J, Sanz L, Moscat J. 1996. The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C. Cell 86:777-786.
-
(1996)
Cell
, vol.86
, pp. 777-786
-
-
Diaz-Meco, M.T.1
Municio, M.M.2
Frutos, S.3
Sanchez, P.4
Lozano, J.5
Sanz, L.6
Moscat, J.7
-
13
-
-
0033538336
-
Inactivation of the inhibitory kappaB protein kinase/nuclear factor kappaB pathway by Par-4 expression potentiates tumor necrosis factor alpha-induced apoptosis
-
Diaz-Meco MT, Lallena MJ, Monjas A, Frutos S, Moscat J. 1999. Inactivation of the inhibitory kappaB protein kinase/nuclear factor kappaB pathway by Par-4 expression potentiates tumor necrosis factor alpha-induced apoptosis. J Biol Chem 274:19606-19618.
-
(1999)
J Biol Chem
, vol.274
, pp. 19606-19618
-
-
Diaz-Meco, M.T.1
Lallena, M.J.2
Monjas, A.3
Frutos, S.4
Moscat, J.5
-
14
-
-
0043133881
-
Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells
-
El-Guendy N, Zhao Y, Gurumurthy S, Burikhanov R, Rangnekar VM. 2003. Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells. Mol Cell Biol 23:5516-5525.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5516-5525
-
-
El-Guendy, N.1
Zhao, Y.2
Gurumurthy, S.3
Burikhanov, R.4
Rangnekar, V.M.5
-
15
-
-
0242585506
-
Genetic inactivation of Par4 results in hyperactivation of NF-kappaB and impairment of JNK and p38
-
Garcia-Cao I, Lafuente MJ, Criado LM, Diaz-Meco MT, Serrano M, Moscat J. 2003. Genetic inactivation of Par4 results in hyperactivation of NF-kappaB and impairment of JNK and p38. EMBO Rep 4:307-312.
-
(2003)
EMBO Rep
, vol.4
, pp. 307-312
-
-
Garcia-Cao, I.1
Lafuente, M.J.2
Criado, L.M.3
Diaz-Meco, M.T.4
Serrano, M.5
Moscat, J.6
-
16
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. 2000. The hallmarks of cancer. Cell 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
18
-
-
10544225383
-
A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1
-
Johnstone RW, See RH, Sells SF, Wang J, Muthukkumar S, Englert C, Haber DA, Licht JD, Sugrue SP, Roberts T, Rangnekar VM, Shi Y. 1996. A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1. Mol Cell Biol 16:6945-6956.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6945-6956
-
-
Johnstone, R.W.1
See, R.H.2
Sells, S.F.3
Wang, J.4
Muthukkumar, S.5
Englert, C.6
Haber, D.A.7
Licht, J.D.8
Sugrue, S.P.9
Roberts, T.10
Rangnekar, V.M.11
Shi, Y.12
-
19
-
-
0035042458
-
Discovery and design of selective cyclooxygenase-2 inhibitors as non-ulcerogenic, anti-inflammatory drugs with potential utility as anti-cancer agents
-
Kalgutkar AS, Zhao Z. 2001. Discovery and design of selective cyclooxygenase-2 inhibitors as non-ulcerogenic, anti-inflammatory drugs with potential utility as anti-cancer agents. Curr Drug Targets 2:79-106.
-
(2001)
Curr Drug Targets
, vol.2
, pp. 79-106
-
-
Kalgutkar, A.S.1
Zhao, Z.2
-
20
-
-
0042470558
-
ZIP kinase triggers apoptosis from nuclear PML oncogenic domains
-
Kawai T, Akira S, Reed JC. 2003. ZIP kinase triggers apoptosis from nuclear PML oncogenic domains. Mol Cell Biol 23:6174-6186.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 6174-6186
-
-
Kawai, T.1
Akira, S.2
Reed, J.C.3
-
21
-
-
15144342086
-
Identification of two common regions of allelic loss in chromosome arm 12q in human pancreatic cancer
-
Kimura M, Furukawa T, Abe T, Yatsuoka T, Youssef EM, Yokoyama T, Ouyang H, Ohnishi Y, Sunamura M, Kobari M, Matsuno S, Horii A. 1998. Identification of two common regions of allelic loss in chromosome arm 12q in human pancreatic cancer. Cancer Res 58:2456-2460.
-
(1998)
Cancer Res
, vol.58
, pp. 2456-2460
-
-
Kimura, M.1
Furukawa, T.2
Abe, T.3
Yatsuoka, T.4
Youssef, E.M.5
Yokoyama, T.6
Ouyang, H.7
Ohnishi, Y.8
Sunamura, M.9
Kobari, M.10
Matsuno, S.11
Horii, A.12
-
22
-
-
0035976314
-
Dlk/ZIP kinase-induced apoptosis in human medulloblastoma cells: Requirement of the mitochondrial apoptosis pathway
-
Kogel D, Reimertz C, Mech P, Poppe M, Fruhwald MC, Engemann H, Scheidtmann KH, Prehn JH. 2001. Dlk/ZIP kinase-induced apoptosis in human medulloblastoma cells: Requirement of the mitochondrial apoptosis pathway. Br J Cancer 85:1801-1808.
-
(2001)
Br J Cancer
, vol.85
, pp. 1801-1808
-
-
Kogel, D.1
Reimertz, C.2
Mech, P.3
Poppe, M.4
Fruhwald, M.C.5
Engemann, H.6
Scheidtmann, K.H.7
Prehn, J.H.8
-
23
-
-
0141514011
-
Regulation of mature T lymphocyte proliferation and differentiation by Par-4
-
Lafuente MJ, Martin P, Garcia-Cao I, Diaz-Meco MT, Serrano M, Moscat J. 2003. Regulation of mature T lymphocyte proliferation and differentiation by Par-4. EMBO J 22:4689-4698.
-
(2003)
EMBO J
, vol.22
, pp. 4689-4698
-
-
Lafuente, M.J.1
Martin, P.2
Garcia-Cao, I.3
Diaz-Meco, M.T.4
Serrano, M.5
Moscat, J.6
-
24
-
-
0034901756
-
Differential expression levels of Par-4 in melanoma
-
Lucas T, Pratscher B, Krishnan S, Fink D, Gunsberg P, Wolschek M, Wacheck V, Muster T, Romirer I, Wolff K, Pehamberger H, Eichler HG, Rangnekar VM, Jansen B. 2001. Differential expression levels of Par-4 in melanoma. Melanoma Res 11:379-383.
-
(2001)
Melanoma Res
, vol.11
, pp. 379-383
-
-
Lucas, T.1
Pratscher, B.2
Krishnan, S.3
Fink, D.4
Gunsberg, P.5
Wolschek, M.6
Wacheck, V.7
Muster, T.8
Romirer, I.9
Wolff, K.10
Pehamberger, H.11
Eichler, H.G.12
Rangnekar, V.M.13
Jansen, B.14
-
25
-
-
0033570123
-
Oncogenic Ras sensitizes cells to apoptosis by Par-4
-
Nalca A, Qiu SG, El-Guendy N, Krishnan S, Rangnekar VM. 1999. Oncogenic Ras sensitizes cells to apoptosis by Par-4. J Biol Chem 274:29976-29983.
-
(1999)
J Biol Chem
, vol.274
, pp. 29976-29983
-
-
Nalca, A.1
Qiu, S.G.2
El-Guendy, N.3
Krishnan, S.4
Rangnekar, V.M.5
-
26
-
-
0033518129
-
Interaction partners of Dlk/ZIP kinase: Co-expression of Dlk/ZIP kinase and Par-4 results in cytoplasmic retention and apoptosis
-
Page G, Kogel D, Rangnekar V, Scheidtmann KH. 1999. Interaction partners of Dlk/ZIP kinase: Co-expression of Dlk/ZIP kinase and Par-4 results in cytoplasmic retention and apoptosis. Oncogene 18:7265-7273.
-
(1999)
Oncogene
, vol.18
, pp. 7265-7273
-
-
Page, G.1
Kogel, D.2
Rangnekar, V.3
Scheidtmann, K.H.4
-
27
-
-
0008881181
-
Mutually exclusive expression patterns of Bcl-2 and Par-4 in human prostate tumors consistent with down-regulation of Bcl-2 by Par-4
-
Qiu G, Ahmed M, Sells SF, Mohiuddin M, Weinstein MH, Rangnekar VM. 1999a. Mutually exclusive expression patterns of Bcl-2 and Par-4 in human prostate tumors consistent with down-regulation of Bcl-2 by Par-4. Oncogene 18:623-631.
-
(1999)
Oncogene
, vol.18
, pp. 623-631
-
-
Qiu, G.1
Ahmed, M.2
Sells, S.F.3
Mohiuddin, M.4
Weinstein, M.H.5
Rangnekar, V.M.6
-
28
-
-
0033604464
-
Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformation
-
Qiu SG, Krishnan S, el-Guendy N, Rangnekar VM. 1999b. Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformation. Oncogene 18:7115-7123.
-
(1999)
Oncogene
, vol.18
, pp. 7115-7123
-
-
Qiu, S.G.1
Krishnan, S.2
El-Guendy, N.3
Rangnekar, V.M.4
-
29
-
-
0029693498
-
Bcl-2 family proteins and the regulation of programmed cell death in leukemia and lymphoma
-
Reed JC, Miyashita T, Krajewski S, Takayama S, Aime-Sempe C, Kitada S, Sato T, Wang HG, Harigai M, Hanada M, Krajewska M, Kochel K, Millan J, Kobayashi H. 1996. Bcl-2 family proteins and the regulation of programmed cell death in leukemia and lymphoma. Cancer Treat Res 84:31-72.
-
(1996)
Cancer Treat Res
, vol.84
, pp. 31-72
-
-
Reed, J.C.1
Miyashita, T.2
Krajewski, S.3
Takayama, S.4
Aime-Sempe, C.5
Kitada, S.6
Sato, T.7
Wang, H.G.8
Harigai, M.9
Hanada, M.10
Krajewska, M.11
Kochel, K.12
Millan, J.13
Kobayashi, H.14
-
30
-
-
0038330739
-
THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis- response-4 (Par-4) to PML nuclear bodies
-
Roussigne M, Cayrol C, Clouaire T, Amalric F, Girard JP. 2003. THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis-response-4 (Par-4) to PML nuclear bodies. Oncogene 22:2432-2442.
-
(2003)
Oncogene
, vol.22
, pp. 2432-2442
-
-
Roussigne, M.1
Cayrol, C.2
Clouaire, T.3
Amalric, F.4
Girard, J.P.5
-
32
-
-
0038648563
-
Regions of allelic imbalance in the distal portion of chromosome 12q in gastric cancer
-
Schneider BG, Rha SY, Chung HC, Bravo JC, Mera R, Torres JC, Plaisance KT, Jr., Schlegel R, McBride CM, Reveles XT, Leach RJ. 2003. Regions of allelic imbalance in the distal portion of chromosome 12q in gastric cancer. Mol Pathol 56:141-149.
-
(2003)
Mol Pathol
, vol.56
, pp. 141-149
-
-
Schneider, B.G.1
Rha, S.Y.2
Chung, H.C.3
Bravo, J.C.4
Mera, R.5
Torres, J.C.6
Plaisance Jr., K.T.7
Schlegel, R.8
McBride, C.M.9
Reveles, X.T.10
Leach, R.J.11
-
33
-
-
0028015669
-
Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and-independent prostate cells
-
Sells SF, Wood DP, Jr., Joshi-Barve SS, Muthukumar S, Jacob RJ, Crist SA, Humphreys S, Rangnekar VM. 1994. Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and-independent prostate cells. Cell Growth Differ 5:457-466.
-
(1994)
Cell Growth Differ
, vol.5
, pp. 457-466
-
-
Sells, S.F.1
Wood Jr., D.P.2
Joshi-Barve, S.S.3
Muthukumar, S.4
Jacob, R.J.5
Crist, S.A.6
Humphreys, S.7
Rangnekar, V.M.8
-
34
-
-
0030990094
-
Expression and function of the leucine zipper protein Par-4 in apoptosis
-
Sells SF, Han SS, Muthukkumar S, Maddiwar N, Johnstone R, Boghaert E, Gillis D, Liu G, Nair P, Monnig S, Collini P, Mattson MP, Sukhatme VP, Zimmer SG, Wood DP, Jr., McRoberts JW, Shi Y, Rangnekar VM. 1997. Expression and function of the leucine zipper protein Par-4 in apoptosis. Mol Cell Biol 17:3823-3832.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3823-3832
-
-
Sells, S.F.1
Han, S.S.2
Muthukkumar, S.3
Maddiwar, N.4
Johnstone, R.5
Boghaert, E.6
Gillis, D.7
Liu, G.8
Nair, P.9
Monnig, S.10
Collini, P.11
Mattson, M.P.12
Sukhatme, V.P.13
Zimmer, S.G.14
Wood Jr., D.P.15
McRoberts, J.W.16
Shi, Y.17
Rangnekar, V.M.18
-
35
-
-
0029899181
-
Molecular thanatopsis: A discourse on the BCL2 family and cell death
-
Yang E, Korsmeyer SJ. 1996. Molecular thanatopsis: A discourse on the BCL2 family and cell death. Blood 88:386-401.
-
(1996)
Blood
, vol.88
, pp. 386-401
-
-
Yang, E.1
Korsmeyer, S.J.2
-
36
-
-
0034128988
-
Par-4, a proapoptotic gene, is regulated by NSAIDs in human colon carcinoma cells
-
Zhang Z, DuBois RN. 2000. Par-4, a proapoptotic gene, is regulated by NSAIDs in human colon carcinoma cells. Gastroenterology 118:1012-1017.
-
(2000)
Gastroenterology
, vol.118
, pp. 1012-1017
-
-
Zhang, Z.1
DuBois, R.N.2
|