Introduction of trifluoromethyl group into diphenyl diselenide molecule alters its toxicity and protective effect against damage induced by 2-nitropropane in rats

Experimental and Toxicologic Pathology

Volumn 61, Issue 3, 2009, Pages 197-203

  Wilhelm, Ethel A ^a   Jesse, Cristiano R ^a   Nogueira, Cristina W ^a   Savegnago, Lucielli ^b  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^b UNIVERSIDADE FEDERAL DO PAMPA   (Brazil)

Author keywords

2 Nitropropane; Antioxidant; Diphenyl diselenide; Hepatic damage; Liver; m Trifluoromethyl diphenyl diselenide; Selenium

Indexed keywords

2 NITROPROPANE; 3 TRIFLUOROMETHYL DIPHENYL DISELENIDE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CATALASE; CREATININE; DIPHENYL DISELENIDE; GAMMA GLUTAMYLTRANSFERASE; METHYL GROUP; SELENIUM DERIVATIVE; UNCLASSIFIED DRUG; UREA;

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME ACTIVITY; LETHAL DOSE; MALE; NONHUMAN; PLASMA; RAT; UREA BLOOD LEVEL;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BENZENE DERIVATIVES; GAMMA-GLUTAMYLTRANSFERASE; KIDNEY; LETHAL DOSE 50; LIVER; MALE; NITROPARAFFINS; ORGANOSELENIUM COMPOUNDS; PROPANE; RATS; RATS, WISTAR;

RATTUS;

EID: 67349165895     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2008.08.003     Document Type: Article

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