Route of administration influences substitution patterns in rats trained to discriminate methadone vs. vehicle

Drug and Alcohol Dependence

Volumn 103, Issue 3, 2009, Pages 124-130

  Vann, Robert E ^a   Wise, Laura E ^a   Varvel, Stephen A ^a   Philibin, Scott D ^b   Walentiny, D Matthew ^a   Porter, Joseph H ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

(+) Methadone; ( ) Methadone; Drug discrimination; Heroin; Methadone; Morphine; Naltrexone; Opioid; U50 488

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; DIAMORPHINE; METHADONE; MORPHINE; MU OPIATE RECEPTOR; NALTREXONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; DRUG ANTAGONISM; DRUG BIOAVAILABILITY; DRUG DISCRIMINATION; DRUG DOSAGE FORM COMPARISON; DRUG DOSE; DRUG METABOLISM; FIRST PASS EFFECT; MALE; METHADONE TREATMENT; NONHUMAN; OPIATE ADDICTION; PRIORITY JOURNAL; RAT;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ANALGESICS, NON-NARCOTIC; ANIMALS; CHOICE BEHAVIOR; CONDITIONING, OPERANT; DISCRIMINATION (PSYCHOLOGY); HEROIN; INJECTIONS, INTRAPERITONEAL; INJECTIONS, SUBCUTANEOUS; MALE; METHADONE; MORPHINE; NALTREXONE; NARCOTIC ANTAGONISTS; NARCOTICS; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM; VEHICLES;

RATTUS;

EID: 67349164321     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2009.02.015     Document Type: Article

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