Evaluation of pharmacological efficacy of 'insulin-surfoplex' encapsulated polymer vesicles

International Journal of Pharmaceutics

Volumn 373, Issue 1-2, 2009, Pages 107-115

  Rastogi, Rachna ^a,b   Anand, Sneh ^a,b   Koul, Veena ^a,b  

^a INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

In vitro and in vivo evaluation; Insulin; Ion pair complex; Polymerosomes; Surfactant

Indexed keywords

DEOXYCHOLATE SODIUM; EPSILON CAPROLACTONE; MACROGOL 2000; NANOPARTICLE; POLYCAPROLACTONE; RECOMBINANT HUMAN INSULIN; RECOMBINANT HUMAN INSULIN EPSILON CAPROLACTONE MACROGOL 2000 CONJUGATE; SURFACTANT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPLEX FORMATION; CONJUGATION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFICACY; DRUG FORMULATION; DRUG STABILITY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; INSULIN RELEASE; ION PAIR CHROMATOGRAPHY; ION PAIR EXTRACTION; LIPOPHILICITY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; RAT;

AMINES; ANIMALS; BINDING SITES; BIOLOGICAL AVAILABILITY; BLOOD GLUCOSE; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYCHOLIC ACID; DIABETES MELLITUS, EXPERIMENTAL; DRUG CARRIERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HUMANS; HYDROPHOBICITY; INSULIN; MALE; NEPHELOMETRY AND TURBIDIMETRY; POLYESTERS; POLYETHYLENE GLYCOLS; PROTEIN CONFORMATION; RATS; RATS, WISTAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 67349152349     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.01.022     Document Type: Article

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