Comparison of Austrian, Hungarian and Macedonian methicillin-resistant and methicillin-sensitive Staphylococcus aureus strains in relation to prevalence of cytotoxin genes

Microbial Pathogenesis

Volumn 46, Issue 6, 2009, Pages 328-336

  Kocsis, Erika ^a   Lagler, Heimo ^b   Pesti, Natasa ^a   Stich, Karin ^b   Kristóf, Katalin ^a   Nagy, Károly ^a   Hermann, Péter ^a   Komka, Kinga ^c   Cekovska, Zaklina ^d   Graninger, Wolfgang ^b   Rozgonyi, Ferenc ^a,e  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^d SS CYRIL AND METHODIUS UNIVERSITY   (Macedonia)

^e SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

Author keywords

Cytotoxin genes; Gene combinations; MRSA; MSSA; Virulence factors

Indexed keywords

ALPHA HEMOLYSIN; BACTERIAL TOXIN; CYTOTOXIN; HEMOLYSIN; PANTON VALENTINE LEUKOCIDIN;

ARTICLE; AUSTRIA; BACTERIAL GENE; BACTERIAL STRAIN; COMPARATIVE STUDY; CONTROLLED STUDY; GENE FREQUENCY; GENETIC VARIABILITY; GEOGRAPHIC ORIGIN; HUMAN; HUNGARY; MACEDONIA (REPUBLIC); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN SENSITIVE STAPHYLOCOCCUS AUREUS; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STRAIN DIFFERENCE;

AUSTRIA; CYTOTOXINS; HEMOLYSIN PROTEINS; HUMANS; HUNGARY; LEUKOCIDINS; MACEDONIA (REPUBLIC); METHICILLIN RESISTANCE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 67349151628     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2009.04.002     Document Type: Article

References (33)

1. Foster T.J., and Höök M. Surface protein adhesins of Staphylococcus aureus. Trends Microbiol 6 (1998) 484-488
2. Dinges M.M., Orwin P.M., and Schlievert P.M. Exotoxins of Staphylococcus aureus. Clin Microbiol Rev 13 (2000) 16-34
3. Kaneko J., and Kamio Y. Bacterial two-component and hetero-heptameric pore-forming cytolytic toxins: structures, pore forming mechanism, and organization of the genes. Biosci Biotechnol Biochem 68 (2004) 981-1003
4. Viero G., Cunaccia R., Prévost G., Werner S., Monteil H., Keller D., et al. Homologous versus heterologous interactions in bicomponent staphylococcal γ-haemolysin pore. Biochem J 394 (2006) 217-225
5. Lina G., Piémont Y., Godail-Gamot F., Bes M., Peter M.O., Gauduchon V., et al. Involvement of Panton-Valentine leukocidin producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis 29 (1999) 1128-1132
6. Dufour P., Gillet Y., Bes M., Lina G., Vandanesch F., Floret D., et al. Community-acquired methicillin-resistant Staphylococcus aureus infections in France: emergence of a single clone that produces Panton-Valentine leukocidin. Clin Infect Dis 35 (2002) 819-824
7. Baggett H.C., Hennessy T.W., Rudolph K., Bruden D., Reasonover A., Parkinson A., et al. Community-onset methicillin-resistant Staphylococcus aureus associated with antibiotic use and the cytotoxin Panton-Valentine leukocidin during a furunculosis outbreak in rural Alaska. J Infect Dis 189 (2004) 1565-1573
8. Bentzmann S., Tristan A., Etienne J., Brousse N., Vandanesh F., and Lina G. Staphylococcus aureus isolates associated with necrotizing pneumonia bind to basement membrane type I and IV collagens and laminin. J Infect Dis 190 (2004) 1506-1515
9. Charlebois E.D., Perdreau-Remington F., Kreiswirth B., Bangsberg D.R., Ciccarone D., Diep B.A., et al. Origins of community strains of methicillin-resistant Staphylococcus aureus. Clin Infect Dis 39 (2004) 47-54
10. Francis J.S., Doherty M.C., Lopatin U., Johnston C.P., Sinha G., Ross T., et al. Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes. Clin Infect Dis 40 (2005) 100-107
11. O'Callaghan R.J., Callegan M.C., Moreau J.M., Green L.C., Foster T.J., Hartford O.M., et al. Specific role of alpha-toxin and beta-toxin during Staphylococcus aureus corneal infection. Infect Immun 65 (1997) 1571-1578
12. Girgis D., Sloop G.D., Reed J.M., and O'Callaghan R.J. Effects of toxin production in a murine model of Staphylococcus aureus keratitis. Invest Ophthalmol Vis Sci 46 (2005) 2064-2070
13. Wu P.Z.J., Zhu H., Stapleton F., Hume E., Aliwarga Y., Thakur A., et al. Effects of α-toxin-deficient Staphylococcus aureus on the production of peripheral corneal ulceration in an animal model. Curr Eye Res 30 (2005) 63-70
14. Prevost G., Couppie P., Prevost P., Gayet S., Petiau P., Cribier B., et al. Epidemiological data on Staphylococcus aureus strains producing synergohymenotropic toxins. J Med Microbiol 42 (1995) 237-245
15. Rozgonyi F., Kocsis E., Kristóf K., and Nagy K. Is MRSA more virulent than MSSA?. Clin Microbiol Infect 13 (2007) 843-845
16. Peacock S.J., Moore C.E., Justice A., Kantzanou M., Story L., Mackie K., et al. Virulent combinations of adhesin and toxin genes in natural populations of Staphylococcus aureus. Infect Immun 70 (2002) 4987-4996
17. Branger C., Gardye C., Galdbart J.C., Deschamps C., and Lambert N. Genetic relationship between methicillin-sensitive and methicillin-resistant Staphylococcus aureus strains from France and from international sources: delineation of genomic groups. J Clin Microbiol 41 (2003) 2946-2951
18. Hallin M., Denis O., Deplano A., De Mendonça R., De Ryck R., Rottiers S., et al. Genetic relatedness between methicillin-susceptible and methicillin-resistant Staphylococcus aureus: results of a national survey. J Antimicrob Chemother 59 (2007) 465-472
19. Lindsay J.A., and Holden M.T.G. Staphylococcus aureus: superbug, super genome?. Trends Microbiol 12 (2004) 378-385
20. von Eiff C., Friedrich A.W., Peters G., and Beckers K. Prevalence of genes encoding for members of the staphylococcal leukotoxin family among clinical isolates of Staphylococcus aureus. Diagn Microbiol Infect Dis 49 (2004) 157-162
21. Novick R.P. Mobile genetic elements and bacterial toxinoses: the superantigen-encoding pathogenicity islands of Staphylococcus aureus. Plasmid 49 (2003) 93-105
22. Schmidt H., and Hensel M. Pathogenicity islands in bacterial pathogenesis. Clin Microbiol Rev 17 (2004) 14-56
23. Carroll J.D., Cafferkey M.T., and Coleman D.C. Serotype F double- and triple-converting phage insertionally inactivate the Staphylococcus aureus β-toxin determinant by a common molecular mechanism. FEMS Microbiol Lett 106 (1993) 147-156
24. Coleman D., Knights J., Russel R., Shanley D., Birbeck T.H., Dougan G., et al. Insertional inactivation of the Staphylococcus aureus beta-toxin by bacteriophage phi 13 occurs by site- and orientation-specific integration of the phi 13 genome. Mol Microbiol 5 (1991) 933-939
25. Smeltzer M.S., Hart M.E., and Iandolo J.J. The effect of lysogeny on the genomic organization of Staphylococcus aureus. Gene 138 (1994) 51-57
26. Majoros L., Papp-Falusi E., Andirkó I., and Rozgonyi F. A comparative study on the virulence of methicillin-resistant and methicillin-sensitive Staphylococcus aureus strains. Acta Microbiol Hung 43 (1996) 160
27. Aarestrup F.M., Larsen H.D., Eriksen N.H.R., Elsberg C.S., and Jensen N.E. Frequency of α- and β-haemolysin in Staphylococcus aureus of bovine and human origin. APMIS 107 (1999) 425-430
28. Wagner P.L., and Waldor M.K. Bacteriophage control of bacterial virulence. Infect Immun 70 (2002) 3985-3993
29. Johnsson D., Mölling P., Strålin K., and Söderquist B. Detection of Panton-Valentine leukocidin gene in Staphylococcus aureus by lightcycler PCR: clinical and epidemiological aspects. Clin Microbiol Infect 10 (2004) 884-889
30. Louie L., Matsumura S.O., Choi E., Louie M., and Simor A.E. Evaluation of three rapid methods for detection of methicillin resistance in Staphylococcus aureus. J Clin Microbiol 38 (2000) 2170-2173
31. Straub J.A., Hertel C., and Hammes W.P. A 23S rDNA-targeted polymerase chain reaction-based system for detection of Staphylococcus aureus in meat starter cultures and dairy products. J Food Prot 62 (1999) 1150-1156
32. Salisbury S.M., Sabatini L.M., and Spiegel C.A. Identification of methicillin-resistant staphylococci by polymerase chain reaction assay. Am J Clin Pathol 107 (1997) 368-373
33. Jarraud S., Mougel C., Thioulouse J., Lina G., Meugnier H., Forey F., et al. Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (alleles), and human disease. Infect Immun 70 (2002) 631-641