DNA-damaged polyploid cancer cells can reverse to diploidy: An ordered, but little understood, process of genomic reduction [with reference to the previous comments of Forer (2008) and Wheatley (2008a and b)]

Cell Biology International

Volumn 33, Issue 6, 2009, Pages 702-703

  Martin, François ^a   Puig, Pierre Emmanuel ^a   Ghiringhelli, François ^a   Chauffert, Bruno ^a  

^a Chu   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; MELPHALAN; MITOMYCIN C; OXALIPLATIN;

CANCER CELL; CELL PROLIFERATION; CELL SELECTION; DIPLOIDY; DNA DAMAGE; DNA HYBRIDIZATION; ENDOREDUPLICATION; HUMAN; LETTER; NONHUMAN; POLYPLOIDY; X IRRADIATION;

ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DIPLOIDY; DNA DAMAGE; GENOME, HUMAN; HUMANS; NEOPLASMS; POLYPLOIDY;

EID: 67349150465     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2009.02.016     Document Type: Letter

References (17)

1. Berger C.A. Multiplication and reduction of somatic chromosome groups as a regular developmental process in the mosquito, culex pipiens (1938), Carnegie Inst Wash Publn p. 496
2. Erenpreisa J., and Cragg M.S. Cancer: a matter of life cycle?. Cell Biol Int 31 (2007) 1507-1510
3. Erenpreisa J.A., Cragg M.S., Fringes B., Sharakhov I., and Illidge T.M. Release of mitotic descendants by giant cells from irradiated Burkitt's lymphoma cell line. Cell Biol Int 24 (2000) 635-648
4. Erenpreisa J., Kalejs M., and Cragg M.S. Mitotic catastrophe and endomitosis in tumour cells: an evolutionary key to a molecular solution. Cell Biol Int 29 (2005) 1012-1018
5. Forer A. Ploidy and division in cancer and mosquito hind gut cells. Cell Biol Int 33 (2009) 247-252
6. Grell S.M. Cytological studies in Culex. I. Somatic reduction divisions. Genetics 31 (1946) 60-76 p. 77-94
7. Illidge T.M., Cragg M.S., Fringes B., Olive P., and Erenpreisa J.A. Polyploid giant cells provide a survival mechanism for p53 mutant cells after DNA damage. Cell Biol Int 24 (2000) 621-633
8. Kalejs M., Ivanov A., Plakhins G., Cragg M.S., Emzinsh D., Illidge T.M., et al. Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe. BMC Cancer 6 (2006) 6
9. Nagl W. Polyploidy in differentiation and evolution. Int J Cell Clon 8 (1990) 216-223
10. Puig P.E., Guilly M.N., Bouchot A., Droin N., Cathelin D., Bouyer F., et al. Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy. Cell Biol Int 32 (2008) 1031-1043
11. Ravid K., Lu J., Zimmet J.M., and Jones M.R. Roads to polyploidy: the megakaryocyte example. J Cell Physiol 190 (2002) 7-20
12. Revenkoa E., and Jessberger R. Keeping sister chromatids together: cohesins in meiosis. Reproduction 130 (2005) 783-790
13. Storchova Z., and Pellman D. From polyploidy to aneuploidy, genome instability and cancer. Nat Rev Mol Cell Biol 5 (2004) 45-54
14. Sundaram M., Guernsey D.L., Rajaraman M.M., and Rajaraman R. Neosis: a novel type of cell division in cancer. Cancer Biol Ther 3 (2004) 207-218
15. Walen K.H. Bipolar genome reductional division of human near-senescent polyploid fibroblast cells. Cancer Genet Cytogenet 173 (2007) 43-50
16. Wheatley D.N. Growing evidence of the repopulation of regressed tumours by the division of giant cells. Cell Biol Int 32 (2008) 1029-1030
17. Wheatley D.N. Editorial comment on "centrosome overduplication and mitotic instability in PKD2 transgenic lines by Burtey et al.". Cell Biol Int 32 (2008) 1193-1198