A heat-activated and thermoresistant telomerase activity in Leishmania major Friedlin

Acta Tropica

Volumn 111, Issue 1, 2009, Pages 86-89

  Galindo, Maria Mercedes ^a   Rodriguez, Evelyn ^a   Rojas, Maria Gabriela ^a   Figarella, Katherine ^a   Campelo, Riward ^a   Ramírez, Jose Luis ^a,b  

^a Instituto de Estudios Avanzados   (Venezuela)

^b UNITED NATIONS   (United States)

Author keywords

Highly active; Leishmania telomerase; Thermoresistant

Indexed keywords

PROTEIN; TELOMERASE;

CONCENTRATION (COMPOSITION); DRUG; ENZYME ACTIVITY; PARASITE; PROTEIN;

ARTICLE; DENATURATION; DRUG TARGETING; ENZYME ACTIVITY; HEAT TOLERANCE; LEISHMANIA MAJOR; NONHUMAN; PARAMETER; SEQUENCE ANALYSIS;

ANIMALS; HOT TEMPERATURE; LEISHMANIA MAJOR; PROTEIN DENATURATION; PROTOZOAN PROTEINS; TELOMERASE;

LEISHMANIA MAJOR;

EID: 67349146584     PISSN: 0001706X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actatropica.2009.02.002     Document Type: Article

References (11)

1. Akiyama Y., Maesawa C., Wada K., Fujisawa K., Itabashi T., Noda Y., et al. Human 1PinX1, a potent telomerase inhibitor, is not involved in human gastrointestinal tract carcinoma. Oncol. Rep. 11 (2004) 71-874
2. Boulé J.B., Vega L.R., and Zakian V.A. The yeast Pif1p helicase removes telomerase from telomeric DNA. Nature 438 (2005) 57-61
3. Cano M.I., Dungan J.M., Agabian N., and Blackburn E.H. Telomerase in kinetoplastid parasitic protozoa. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 3616-3621
4. Chiurillo M.A., Cano I., Da Silveira J.F., and Ramirez J.L. Organization of telomeric and sub-telomeric regions of chromosomes from the protozoan parasite Trypanosoma cruzi. Mol. Biochem. Parasitol. 100 (1999) 173-183
5. Chiurillo M.A., Beck A.E., Devos T., Myler P.J., Stuart K., and Ramirez J.L. Cloning and characterization of Leishmania donovani telomeres. Exp. Parasitol. 94 (2000) 248-258
6. Chiurillo M.A., and Ramírez J.L. Characterization of Leishmania major Friedlin telomeric terminus. Mem. Inst. Oswaldo Cruz 97 (2002) 343-346
7. Cohen S.B., Graham M.E., Lovrecz G.O., Bache N., Robinson P.J., and Reddel R.R. Protein composition of catalytically active human telomerase from immortal cells. Science 315 (2007) 1850-1853
8. Fu G., and Barker D.C. Characterisation of Leishmania telomeres reveals unusual telomeric repeats and conserved telomere-associated sequence. Nucleic Acids Res. 26 (1998) 2161-2167
9. Kim N.W., Piatyszek M.A., Prowse K.R., Harley C.B., West M.D., Ho P.L., et al. Specific association of human telomerase activity with immortal cells and cancer. Science 266 (1994) 2011-2015
10. Lingner J., Hughes T.R., Shevchenko A., Mann M., Lundblad V., and Cech T.R. Reverse transcriptase motifs in the catalytic subunit of telomerase. Science 276 (1997) 61-567
11. Mahmood R., and Ray D.S. Nuclear extracts of Crithidia fasciculata contain a factor(s) that binds to the 5′-untranslated regions of TOP2 and RPA1 mRNAs containing sequences required for their cell cycle regulation. J. Biol. Chem. 273 (1998) 23729-23734