Activation of MMP8 and MMP13 by angiotensin II correlates to severe intra-plaque hemorrhages and collagen breakdown in atherosclerotic lesions with a vulnerable phenotype

Atherosclerosis

Volumn 204, Issue 1, 2009, Pages 26-33

  Cheng, Caroline ^a   Tempel, Dennie ^a   van Haperen, Rien ^a   van Damme, Luc ^a   Algür, Meryem ^a   Krams, Rob ^a   de Crom, Rini ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Angiotensin II; Atherosclerosis; Matrix metalloproteinase

Indexed keywords

ANGIOTENSIN II; APOENZYME; COLLAGEN TYPE 1; COLLAGENASE 3; NEUTROPHIL COLLAGENASE; PROCOLLAGEN; PROCOLLAGEN 5ALPHA3; TISSUE INHIBITOR OF METALLOPROTEINASE 4; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DIAMETER; ARTERY RUPTURE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; CAROTID ARTERY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MODEL; DISEASE SEVERITY; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROSIS; GENE EXPRESSION; GENE EXPRESSION PROFILING; KNOCKOUT MOUSE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SHEAR STRESS;

ANGIOTENSIN II; ANIMALS; APOLIPOPROTEINS E; BLOOD PRESSURE; CAROTID ARTERY DISEASES; CAROTID ARTERY, COMMON; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; FIBROSIS; GENE EXPRESSION PROFILING; HEMORRHAGE; INFUSION PUMPS, IMPLANTABLE; INFUSIONS, SUBCUTANEOUS; MACROPHAGES; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 8; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE; PROCOLLAGEN; SEVERITY OF ILLNESS INDEX; TISSUE INHIBITOR OF METALLOPROTEINASES;

EID: 67349136516     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.01.025     Document Type: Article

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