Neurotoxic and immunotoxic effects of Indole-3-butyric acid on rats at subacute and subchronic exposure

NeuroToxicology

Volumn 30, Issue 3, 2009, Pages 382-385

  Yilmaz, Zeycan ^a   Celik, Ismail ^a  

^a YUZUNCU YIL UNIVERSITY   (Turkey)

Author keywords

Immunotoxic; Indole 3 butyric acid; Neurotoxic; Rat

Indexed keywords

ACETYLCHOLINESTERASE; ADENOSINE DEAMINASE; BIOLOGICAL MARKER; CHOLINESTERASE; INDOLEBUTYRIC ACID; MYELOPEROXIDASE; PHYTOHORMONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; IMMUNOLOGICAL MONITORING; IMMUNOTOXICITY; LONG TERM EXPOSURE; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ACETYLCHOLINESTERASE; ADENOSINE DEAMINASE; ANIMALS; BIOLOGICAL MARKERS; BUTYRYLCHOLINESTERASE; IMMUNOTOXINS; INDOLES; MALE; NEUROTOXINS; PEROXIDASE; PLANT GROWTH REGULATORS; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

RATTUS;

EID: 67349135662     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2009.03.002     Document Type: Article

References (31)

1. Aratani Y., Koyama H., Nyui S., Suzuki K., Kura F., and Maeda N. Severe impairment in early host defense against Candida albicans in mice deficient in myeloperoxidase. Infect Immun 67 (1999) 1828-1836
2. Belloni F.L., Rubio R., and Berne R.M. Intracellular adenosine in isolated rat liver cells. Arch Eur J Physiol 400 (1984) 106-108
3. Bradley P.P., Priebat D.A., Christensen R.D., and Rothstein G. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78 (1982) 206-209
4. Candeias L.P., Folkes L.K., Porssa M., Parrick J., and Wardman P. Enhancement of lipid peroxidation by indole-3-acetic acid and derivates: substituent effects. Free Radic Res 23 (1995) 403-418
5. Celik I., and Kara M. The effects of some plant growth regulators on activity of eight serum enzymes in-vitro. J Environ Sci Health A 32 (1997) 1755-1761
6. Celik I., Ozbek H., and Tuluce Y. Effects of subchronic treatment of some plant growth regulators on serum enzyme levels in rats. Tr J Biol 26 (2002) 73-76
7. Celik I., and Tuluce Y. Effects of Indoleacetic acid and Kinetin on lipid peroxidation and antioxidant defense in various tissues of rats. Pest Biochem Phys 84 (2006) 49-54
8. Celik I., Tuluce Y., and Isi{dotless}k I. Evaluation of toxicity of abcisic acid and gibberellic acid in rats: 50 days drinking water study. J Enzym Inhib Med Chem 22 (2007) 219-226
9. Celik I., Tuluce Y., and Isi{dotless}k I. Influence of subacute treatment of some plant growth regulators on serum marker enzymes and erythrocyte and tissue antioxidant defense and lipid peroxidation in rats. J Biochem Mol Tox 20 (2006) 174-182
10. Celik I., Tuluce Y., and Türker M. Antioxidant and immune potential marker enzymes assessment in the various tissues of rats exposed to indoleacetic acid and kinetin: a drinking water study. Pest Biochem Phys 86 (2006) 180-185
11. Cokuggras A.N., and Bodur E. Comparative effects of two plant growth regulators; indole-3-acetic acid and chlorogenic acid on human and horse serum butyrylcholinesterase. Pest Biochem Phys 77 (2003) 24-33
12. Das B.K., and Mukherjee S.C. Chronic toxic effects of quinalphos on some biochemical parameters in Labeo rohita (Ham.). Toxicol Lett 114 (2000) 11-18
13. de Melo M.P., de Lima T.M., Pithon-Curi T.C., and Curi R. The mechanism of indole acetic acid cytotoxicity. Toxicol Lett 14 (2004) 103-111
14. Deby-Dupont G., Deby C., and Lamy M. Neutrophil myeloperoxidase revisited: it's role in health and disease. Intensivmed Notfallmed 36 (1999) 500-513
15. Ellman G.L., Courtney K.D., Andres V., and Featherstone R.M. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7 (1963) 88
16. 3. Oncology 45 (1988) 61-64
17. Escartin E., and Porte C. Acetylcholinesterase inhibition in the Crayfish Procambarus clarkii exposed to fenitrothion. Ecotoxicol Environ Safe 34 (1996) 160-164
18. Furukawa S., Abe M., Usuda K., and Ogawa I. Indole-3-acetic acid induces microencephaly in rat fetuses. Toxicol Pathol 32 (2004) 659-667
19. Giusti G. In: Bergmeyer H.U. (Ed). Methods of Enzymatic Analysis vol. 2 (1974), Academic Press, New York 1092-1099
20. Green R.D. Release of Ado by C1300 neuroblastoma cells in tissue culture. J Supramol Struct 13 (1980) 175-182
21. Green H., and Chan T. Pyrimidine starvation induced by adenosine in fibroblasts and lymphoid cells: role of adenosine deaminase. Science 182 (1973) 836
22. Haqqani S., Sandhu J.K., and Birnboim H.C. A myeloperoxidase-specific assay based upon bromide dependent chemiluminescence of luminol. Anal Biochem 273 (1999) 126-132
23. John J.A., Blogg C.D., Murray F.J., Schwetz B.A., and Gehring P.J. Teratogenic effects of the plant hormone indole-3-acetic acid in mice and rats. Teratology 19 (1979) 321-324
24. McConnico R.S., Weinstock D., Poston M.E., and Malcolm C. Myeloperoxidase activity of the large intestine in an equine model of acute colitis. Am J Vet Res 60 (1999) 807-813
25. Mickel L.G. "Plant growth regulators" controlling biological behavior with chemicals. Chem Eng News 56 (1978) 18
26. Nimit Y., Skolnick P., and Daly J.W. Adenosine and cyclic AMP in rat cerebral cortical slices: effects of adenosine uptake inhibitors and adenosine deaminase inhibitors. J Neurochem 36 (1981) 908-912
27. Ozmen M., Topcuoglu S.F., Bozcuk S., and Bozcuk N.A. Effects of abscisic acid and gibberellic acid on sexual differentiation and some physiological parameters of laboratory mice. Tr J Biol 19 (1995) 357-364
28. Phillis J.W. Adenosine in the control of the cerebral circulation. Cerebrovasc Brain Metab Rev 1 (1989) 26-54
29. Szabo A., and Nemcsok J. The effect of pesticides on carp (Cyprinus carpio). Acetylcholinesterase and its biochemical characterization. Ecotoxicol Environ Safe 23 (1992) 39-45
30. Tuluce Y., and Celik I. Influence of subacute and subchronic treatment of abcisic acid and gibberellic acid on serum marker enzymes and erythrocyte and tissue antioxidant defense systems and lipid peroxidation in rats. Pest Biochem Phys 86 (2006) 85-92
31. Zetterstrom T., Vernet L., Ungerstedt U., Tossman U., Jonzon B., and Fredholm B.B. Purine levels in the intact rat brain: studies with an implanted perfused hollow fiber. Neurosci Lett 29 (1982) 111-115