Complement protein C3 binding to Bacillus anthracis spores enhances phagocytosis by human macrophages

Microbial Pathogenesis

Volumn 46, Issue 6, 2009, Pages 306-314

  Premanandan, Christopher ^a   Storozuk, Craig A ^a   Clay, Corey D ^a   Lairmore, Michael D ^a,b   Schlesinger, Larry S ^a   Phipps, Andrew J ^c  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c BATTELLE MEMORIAL INSTITUTE   (United States)

Author keywords

Anthrax; Bacillus anthracis; Complement; Macrophage

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3B; IMMUNOGLOBULIN G; OPSONIN;

ANTHRAX; ANTIGEN BINDING; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL SPORE; CELL ACTIVATION; CELL SURFACE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LUNG; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; MONOCYTE; NONHUMAN; OPSONIZATION; PATHOGENESIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BINDING; SERUM;

ANTHRAX; ANTIBODIES, BACTERIAL; BACILLUS ANTHRACIS; CELLS, CULTURED; COMPLEMENT C3; COMPLEMENT C4; COMPLEMENT C7; HUMANS; IMMUNOGLOBULIN G; MACROPHAGES; OPSONIN PROTEINS; PHAGOCYTOSIS; SPORES, BACTERIAL;

BACILLUS ANTHRACIS;

EID: 67349130526     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2009.03.004     Document Type: Article

References (39)

1. Pile J.C., Malone J.D., Eitzen E.M., and Friedlander A.M. Anthrax as a potential biological warfare agent. Arch Intern Med 158 (1998) 429-434
2. Dixon T.C., Meselson M., Guillemin J., and Hanna P.C. Anthrax. N Engl J Med 341 (1999) 815-826
3. Hanna P.C., and Ireland J.A. Understanding Bacillus anthracis pathogenesis. Trends Microbiol 7 (1999) 180-182
4. Dixon T.C., Fadl A.A., Koehler T.M., Swanson J.A., and Hanna P.C. Early Bacillus anthracis-macrophage interactions: intracellular survival and escape. Cell Microbiol 2 (2000) 453-463
5. Guidi-Rontani C. The alveolar macrophage: the Trojan horse of Bacillus anthracis. Trends Microbiol 10 (2002) 405-409
6. Cleret A., Quesnel-Hellmann A., Vallon-Eberhard A., Verrier B., Jung S., Vidal D., et al. Lung dendritic cells rapidly mediate anthrax spore entry through the pulmonary route. J Immunol 178 (2007) 7994-8001
7. Gordon S. Pattern recognition receptors: doubling up for the innate immune response. Cell 111 (2002) 927-930
8. Underhill D.M., and Ozinsky A. Phagocytosis of microbes: complexity in action. Annu Rev Immunol 20 (2002) 825-852
9. Ackerman S.K., Friend P.S., Hoidal J.R., and Douglas S.D. Production of C2 by human alveolar macrophages. Immunology 35 (1978) 369-372
10. Cole F.S., Auerbach H.S., Goldberger G., and Colten H.R. Tissue-specific pretranslational regulation of complement production in human mononuclear phagocytes. J Immunol 134 (1985) 2610-2616
11. Strunk R.C., Eidlen D.M., and Mason R.J. Pulmonary alveolar type II epithelial cells synthesize and secrete proteins of the classical and alternative complement pathways. J Clin Invest 81 (1988) 1419-1426
12. Coonrod J.D., and Yoneda K. Complement and opsonins in alveolar secretions and serum of rats with pneumonia due to Streptococcus pneumoniae. Rev Infect Dis 3 (1981) 310-322
13. Ferguson J.S., Weis J.J., Martin J.L., and Schlesinger L.S. Complement protein C3 binding to Mycobacterium tuberculosis is initiated by the classical pathway in human bronchoalveolar lavage fluid. Infect Immun 72 (2004) 2564-2573
14. Kolb W.P., Kolb L.M., Wetsel R.A., Rogers W.R., and Shaw J.O. Quantitation and stability of the fifth component of complement (C5) in bronchoalveolar lavage fluids obtained from non-human primates. Am Rev Respir Dis 123 (1981) 226-231
15. Giclas P.C., King T.E., Baker S.L., Russo J., and Henson P.M. Complement activity in normal rabbit bronchoalveolar fluid. Description of an inhibitor of C3 activation. Am Rev Respir Dis 135 (1987) 403-411
16. Watford W.T., Smithers M.B., Frank M.M., and Wright J.R. Surfactant protein A enhances the phagocytosis of C1q-coated particles by alveolar macrophages. Am J Physiol Lung Cell Mol Physiol 283 (2002) L1011-L1022
17. Gross G.N., Rehm S.R., and Pierce A.K. The effect of complement depletion on lung clearance of bacteria. J Clin Invest 62 (1978) 373-378
18. Schlesinger L.S., Bellinger-Kawahara C.G., Payne N.R., and Horwitz M.A. Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3. J Immunol 144 (1990) 2771-2780
19. Guidi-Rontani C., and Mock M. Macrophage interactions. Curr Top Microbiol Immunol 271 (2002) 115-141
20. Sahu A., and Lambris J.D. Structure and biology of complement protein C3, a connecting link between innate and acquired immunity. Immunol Rev 180 (2001) 35-48
21. Kang P.B., Azad A.K., Torrelles J.B., Kaufman T.M., Beharka A., Tibesar E., et al. The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis. J Exp Med 202 (2005) 987-999
22. Schlesinger L.S., Kaufman T.M., Iyer S., Hull S.R., and Marchiando L.K. Differences in mannose receptor-mediated uptake of lipoarabinomannan from virulent and attenuated strains of Mycobacterium tuberculosis by human macrophages. J Immunol 157 (1996) 4568-4575
23. Merrill L., Dunbar J., Richardson J., and Kuske C.R. Composition of Bacillus species in aerosols from 11 U.S. cities. J Forensic Sci 51 (2006) 559-565
24. Brahmbhatt T.N., Darnell S.C., Carvalho H.M., Sanz P., Kang T.J., Bull R.L., et al. Recombinant exosporium protein BclA of Bacillus anthracis is effective as a booster for mice primed with suboptimal amounts of protective antigen. Infect Immun 75 (2007) 5240-5247
25. Bozue J., Cote C.K., Moody K.L., and Welkos S.L. Fully virulent Bacillus anthracis does not require the immunodominant protein BclA for pathogenesis. Infect Immun 75 (2007) 508-511
26. Goldenberg H.B., McCool T.L., and Weiser J.N. Cross-reactivity of human immunoglobulin G2 recognizing phosphorylcholine and evidence for protection against major bacterial pathogens of the human respiratory tract. J Infect Dis 190 (2004) 1254-1263
27. Vann W.F., Liu T.Y., and Robbins J.B. Bacillus pumilus polysaccharide cross-reactive with meningococcal group A polysaccharide. Infect Immun 13 (1976) 1654-1662
28. Filice G.A., Yeager A.S., and Remington J.S. Diagnostic significance of immunoglobulin M antibodies to Toxoplasma gondii detected after separation of immunoglobulin M from immunoglobulin G antibodies. J Clin Microbiol 12 (1980) 336-342
29. Schlesinger L.S., and Horwitz M.A. A role for natural antibody in the pathogenesis of leprosy: antibody in nonimmune serum mediates C3 fixation to the Mycobacterium leprae surface and hence phagocytosis by human mononuclear phagocytes. Infect Immun 62 (1994) 280-289
30. Lathrop A.A., Huff K., and Bhunia A.K. Prevalence of antibodies reactive to pathogenic and nonpathogenic bacteria in preimmune serum of New Zealand white rabbits. J Immunoassay Immunochem 27 (2006) 351-361
31. Guidi-Rontani C., Levy M., Ohayon H., and Mock M. Fate of germinated Bacillus anthracis spores in primary murine macrophages. Mol Microbiol 42 (2001) 931-938
32. Welkos S., Friedlander A., Weeks S., Little S., and Mendelson I. In-vitro characterisation of the phagocytosis and fate of anthrax spores in macrophages and the effects of anti-PA antibody. J Med Microbiol 51 (2002) 821-831
33. Cote C.K., Van Rooijen N., and Welkos S.L. Roles of macrophages and neutrophils in the early host response to Bacillus anthracis spores in a mouse model of infection. Infect Immun 74 (2006) 469-480
34. Harvill E.T., Lee G., Grippe V.K., and Merkel T.J. Complement depletion renders C57BL/6 mice sensitive to the Bacillus anthracis Sterne strain. Infect Immun 73 (2005) 4420-4422
35. Welkos S.L., Trotter R.W., Becker D.M., and Nelson G.O. Resistance to the Sterne strain of B. anthracis: phagocytic cell responses of resistant and susceptible mice. Microb Pathog 7 (1989) 15-35
36. Welkos S.L., Keener T.J., and Gibbs P.H. Differences in susceptibility of inbred mice to Bacillus anthracis. Infect Immun 51 (1986) 795-800
37. Gaynor C.D., McCormack F.X., Voelker D.R., McGowan S.E., and Schlesinger L.S. Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis by a direct interaction with human macrophages. J Immunol 155 (1995) 5343-5351
38. Weiner M.A., Read T.D., and Hanna P.C. Identification and characterization of the gerH operon of Bacillus anthracis endospores: a differential role for purine nucleosides in germination. J Bacteriol 185 (2003) 1462-1464
39. Tamir H., and Gilvarg C. Density gradient centrifugation for the separation of sporulating forms of bacteria. J Biol Chem 241 (1966) 1085-1090