Micromolar Zn2+ potentiates the cytotoxic action of submicromolar econazole in rat thymocytes: Possible disturbance of intracellular Ca2+ and Zn2+ homeostasis

Toxicology in Vitro

Volumn 23, Issue 4, 2009, Pages 610-616

  Kinazaki, Akio ^a   Sakanashi, Yoko ^b   Oyama, Tomohiro M ^b   Shibagaki, Haruka ^b   Yamashita, Kohei ^b   Hashimoto, Erika ^b   Nishimura, Yumiko ^c   Ishida, Shiro ^a   Okano, Yoshiro ^a   Oyama, Yasuo ^b  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

Author keywords

Cytotoxicity; Econazole; Lymphocyte; Zinc

Indexed keywords

CALCIUM ION; ECONAZOLE; FLUO 3; ZINC CHLORIDE; ZINC ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; HOMEOSTASIS; IMMUNOFLUORESCENCE; LETHAL DOSE; NONHUMAN; RAT; THYMOCYTE; TOXICITY TESTING;

ANIMALS; ANTIFUNGAL AGENTS; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ECONAZOLE; HOMEOSTASIS; LIPID BILAYERS; MALE; RATS; RATS, WISTAR; T-LYMPHOCYTES; ZINC;

MYCOBACTERIUM TUBERCULOSIS; RATTUS;

EID: 67349128608     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.02.001     Document Type: Article

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