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Volumn 33, Issue 8, 2009, Pages 1022-1023

Laromustine: The return of alkylators to non-myeloablative therapy of AML

Author keywords

Alkylating agents; AML; Anthracyclines; ATG; Cloretazine; Cytarabine; Elderly; Laromustine; VNP40101M

Indexed keywords

1,2 BIS(METHYLSULFONYL) 1 (2 CHLOROETHYL) HYDRAZINE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; ALKYLATING AGENT; ANTHRACYCLINE; CYTARABINE; DAUNORUBICIN; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HISTONE H2AX; HYDRAZINE DERIVATIVE; LAROMUSTINE; METHYL ISOCYANATE; UNCLASSIFIED DRUG;

EID: 67349127117     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2009.02.002     Document Type: Editorial
Times cited : (5)

References (8)
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    • A Phase I and pharmacokinetic study of VNP40101M, a novel sulfonylhydrazine alkylating agent, in patients with refractory leukemia
    • Giles F., Thomas D., Garcia-Manero G., et al. A Phase I and pharmacokinetic study of VNP40101M, a novel sulfonylhydrazine alkylating agent, in patients with refractory leukemia. Clin Cancer Res 10 (2004) 2908-2917
    • (2004) Clin Cancer Res , vol.10 , pp. 2908-2917
    • Giles, F.1    Thomas, D.2    Garcia-Manero, G.3
  • 2
    • 33646576509 scopus 로고    scopus 로고
    • Mode of action of the chloroethylating and carbamoylating moieties of the prodrug cloretazine
    • Ishiguro K., Seow H.A., Penketh P.G., et al. Mode of action of the chloroethylating and carbamoylating moieties of the prodrug cloretazine. Mol Cancer Ther 5 (2006) 969-976
    • (2006) Mol Cancer Ther , vol.5 , pp. 969-976
    • Ishiguro, K.1    Seow, H.A.2    Penketh, P.G.3
  • 5
    • 27744493023 scopus 로고    scopus 로고
    • Phase I study of cloretazine (VNP40101M), a novel sulfonylhydrazine alkylating agent, combined with cytarabine in patients with refractory leukemia
    • Giles F., Verstovsek S., Thomas D., et al. Phase I study of cloretazine (VNP40101M), a novel sulfonylhydrazine alkylating agent, combined with cytarabine in patients with refractory leukemia. Clin Cancer Res 11 (2005) 7817-7824
    • (2005) Clin Cancer Res , vol.11 , pp. 7817-7824
    • Giles, F.1    Verstovsek, S.2    Thomas, D.3
  • 6
    • 67349185207 scopus 로고    scopus 로고
    • ®) in elderly patients with de novo poor risk acute myelogenous leukemia
    • [Proc ASH]
    • ®) in elderly patients with de novo poor risk acute myelogenous leukemia. Blood Abs 940 (2008) [Proc ASH]
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    • O'Brien, S.1    Schiller, G.2    Stuart, R.K.3
  • 7
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    • Effect of cloretazine (VNP40101M)on acutemyeloid leukaemia blast cells in vitro as a single agent and combined with cytarabine and daunorubicin
    • Morris K.L., Adams J.A., and Yin J.A.L. Effect of cloretazine (VNP40101M)on acutemyeloid leukaemia blast cells in vitro as a single agent and combined with cytarabine and daunorubicin. Leukemia Res 33 (2009) 1096-1099
    • (2009) Leukemia Res , vol.33 , pp. 1096-1099
    • Morris, K.L.1    Adams, J.A.2    Yin, J.A.L.3
  • 8
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    • Anti-tumor efficacy of Cloretazine (VNP40101M) alone and in combination with fludarabine in murine tumor and human xenograft tumor models
    • Zheng L.M., Li Z., Liu L., et al. Anti-tumor efficacy of Cloretazine (VNP40101M) alone and in combination with fludarabine in murine tumor and human xenograft tumor models. Cancer Chemother Pharmacol 60 (2007) 45-51
    • (2007) Cancer Chemother Pharmacol , vol.60 , pp. 45-51
    • Zheng, L.M.1    Li, Z.2    Liu, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.