메뉴 건너뛰기




Volumn 15, Issue 1, 2009, Pages 56-65

Drug treatment of epilepsy: Options and limitations

Author keywords

Adverse drug effects; Choice of AEDs; Drug resistant epilepsy; Psychiatric comorbidity; Starting AEDs; Stopping AEDs

Indexed keywords

ACETAZOLAMIDE; ANTICONVULSIVE AGENT; BROMIDE; CARBAMAZEPINE; CLONAZEPAM; CLORAZEPATE; DIAZEPAM; ETHOSUXIMIDE; ETHOTOIN; ETIRACETAM; FELBAMATE; FOSPHENYTOIN SODIUM; GABAPENTIN; HARKOSERIDE; LAMOTRIGINE; LORAZEPAM; MEPHENYTOIN; MESUXIMIDE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PREGABALIN; PRIMIDONE; TIAGABINE; TOPIRAMATE; TRIMETHADIONE; UNINDEXED DRUG; VALPROIC ACID; VIGABATRIN; ZONISAMIDE;

EID: 67349117806     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2009.02.030     Document Type: Article
Times cited : (140)

References (36)
  • 1
    • 0004203209 scopus 로고    scopus 로고
    • Levy R.H., Mattson R.H., Meldrum B., and Perucca E. (Eds), Lippincott, Williams & Wilkins, Philadelphia
    • In: Levy R.H., Mattson R.H., Meldrum B., and Perucca E. (Eds). Antiepileptic drugs. 5th ed. (2002), Lippincott, Williams & Wilkins, Philadelphia
    • (2002) Antiepileptic drugs. 5th ed.
  • 3
    • 0004281592 scopus 로고    scopus 로고
    • Engel Jr. J., and Pedley T. (Eds), Wolters Kluwer/Lippincott Williams & Wilkins, Philadelphia
    • In: Engel Jr. J., and Pedley T. (Eds). Epilepsy: a comprehensive textbook. 2nd ed. vols. 1-3 (2007), Wolters Kluwer/Lippincott Williams & Wilkins, Philadelphia
    • (2007) Epilepsy: a comprehensive textbook. 2nd ed. , vol.1-3
  • 4
    • 20444401893 scopus 로고    scopus 로고
    • Immediate versus deferred antiepileptic drug treatment for early epilepsy and single seizures: a randomised controlled trial
    • Marson A., Jacoby A., Johnson A., et al. Immediate versus deferred antiepileptic drug treatment for early epilepsy and single seizures: a randomised controlled trial. Lancet 365 (2005) 2007-2013
    • (2005) Lancet , vol.365 , pp. 2007-2013
    • Marson, A.1    Jacoby, A.2    Johnson, A.3
  • 5
    • 0038196961 scopus 로고    scopus 로고
    • Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs
    • Patsalos P.N., and Perucca E. Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs. Lancet Neurol 2 (2003) 347-356
    • (2003) Lancet Neurol , vol.2 , pp. 347-356
    • Patsalos, P.N.1    Perucca, E.2
  • 6
    • 0033821932 scopus 로고    scopus 로고
    • Enzyme induction and inhibition by new antiepileptic drugs: a review of human studies
    • Strolin-Benedetti M. Enzyme induction and inhibition by new antiepileptic drugs: a review of human studies. Fundam Clin Pharmacol 14 (2000) 301-309
    • (2000) Fundam Clin Pharmacol , vol.14 , pp. 301-309
    • Strolin-Benedetti, M.1
  • 7
    • 34447312716 scopus 로고    scopus 로고
    • Idiosyncratic adverse reactions to antiepileptic drugs
    • Zaccara G., Franciotta D., and Perucca E. Idiosyncratic adverse reactions to antiepileptic drugs. Epilepsia 48 (2007) 1223-1244
    • (2007) Epilepsia , vol.48 , pp. 1223-1244
    • Zaccara, G.1    Franciotta, D.2    Perucca, E.3
  • 8
    • 34447334241 scopus 로고    scopus 로고
    • Rash from antiepileptic drugs: influence by gender, age, and learning disability
    • Alvestad S., Lydersen S., and Brodtkorb E. Rash from antiepileptic drugs: influence by gender, age, and learning disability. Epilepsia 48 (2007) 1360-1365
    • (2007) Epilepsia , vol.48 , pp. 1360-1365
    • Alvestad, S.1    Lydersen, S.2    Brodtkorb, E.3
  • 9
    • 40849139088 scopus 로고    scopus 로고
    • Modern management of epilepsy: a practical approach
    • Elger C.E., and Schmidt D. Modern management of epilepsy: a practical approach. Epilepsy Behav 12 (2008) 510-539
    • (2008) Epilepsy Behav , vol.12 , pp. 510-539
    • Elger, C.E.1    Schmidt, D.2
  • 10
    • 2342514201 scopus 로고    scopus 로고
    • Efficacy and tolerability of the new antiepileptic drugs: I. Treatment of refractory epilepsy. Report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society
    • French J.A., Kanner A.M., Bautista J., et al. Efficacy and tolerability of the new antiepileptic drugs: I. Treatment of refractory epilepsy. Report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society. Epilepsia 45 (2004) 410-423
    • (2004) Epilepsia , vol.45 , pp. 410-423
    • French, J.A.1    Kanner, A.M.2    Bautista, J.3
  • 11
    • 2342512221 scopus 로고    scopus 로고
    • Efficacy and tolerability of the new antiepileptic drugs: I: Treatment of new-onset epilepsy. Report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society
    • French J.A., Kanner A.M., Bautista J., et al. Efficacy and tolerability of the new antiepileptic drugs: I: Treatment of new-onset epilepsy. Report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society. Epilepsia 45 (2004) 401-409
    • (2004) Epilepsia , vol.45 , pp. 401-409
    • French, J.A.1    Kanner, A.M.2    Bautista, J.3
  • 12
    • 33947241772 scopus 로고    scopus 로고
    • The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial
    • Marson A.G., Al-Kharusi A.M., Alwaidh M., et al. The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial. Lancet 369 (2007) 1000-1015
    • (2007) Lancet , vol.369 , pp. 1000-1015
    • Marson, A.G.1    Al-Kharusi, A.M.2    Alwaidh, M.3
  • 13
    • 33947228816 scopus 로고    scopus 로고
    • The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial
    • Marson A.G., Al-Kharusi A.M., Alwaidh M., et al. The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. Lancet 24 369 (2007) 1016-1026
    • (2007) Lancet , vol.24 , Issue.369 , pp. 1016-1026
    • Marson, A.G.1    Al-Kharusi, A.M.2    Alwaidh, M.3
  • 14
    • 39749166363 scopus 로고    scopus 로고
    • For the N166 Levetiracetam Study Group. Levetiracetam for the treatment of idiopathic generalized epilepsy with myoclonic seizures
    • Noachtar S., Andermann E., Meyvisch P., Andermann F., Gough W.B., and Schiemann-Delgado J. For the N166 Levetiracetam Study Group. Levetiracetam for the treatment of idiopathic generalized epilepsy with myoclonic seizures. Neurology 70 (2008) 607-616
    • (2008) Neurology , vol.70 , pp. 607-616
    • Noachtar, S.1    Andermann, E.2    Meyvisch, P.3    Andermann, F.4    Gough, W.B.5    Schiemann-Delgado, J.6
  • 15
    • 0028815488 scopus 로고
    • Monotherapy versus polytherapy in epilepsy
    • Schmidt D., and Gram L. Monotherapy versus polytherapy in epilepsy. CNS Drugs 3 (1995) 194-208
    • (1995) CNS Drugs , vol.3 , pp. 194-208
    • Schmidt, D.1    Gram, L.2
  • 16
    • 0034598762 scopus 로고    scopus 로고
    • Early identification of refractory epilepsy
    • Kwan P., and Brodie M.J. Early identification of refractory epilepsy. N Engl J Med 342 (2000) 314-339
    • (2000) N Engl J Med , vol.342 , pp. 314-339
    • Kwan, P.1    Brodie, M.J.2
  • 17
    • 0002704158 scopus 로고
    • Carbamazepine vs diphenylhydantoin vs. their combination in adult epilepsy
    • Hakkarainen H. Carbamazepine vs diphenylhydantoin vs. their combination in adult epilepsy. Neurology 30 (1980) 354
    • (1980) Neurology , vol.30 , pp. 354
    • Hakkarainen, H.1
  • 18
    • 9144222215 scopus 로고    scopus 로고
    • Adjunctive therapy versus alternative monotherapy in patients with partial epilepsy failing on a single drug: a multicentre, randomised, pragmatic controlled trial
    • Beghi E., Gatti G., Tonini C., et al. Adjunctive therapy versus alternative monotherapy in patients with partial epilepsy failing on a single drug: a multicentre, randomised, pragmatic controlled trial. Epilepsy Res 57 (2003) 1-13
    • (2003) Epilepsy Res , vol.57 , pp. 1-13
    • Beghi, E.1    Gatti, G.2    Tonini, C.3
  • 19
    • 37849053121 scopus 로고    scopus 로고
    • Quantifying the response to antiepileptic drugs: effect of past treatment history
    • Schiller Y., and Najjar Y. Quantifying the response to antiepileptic drugs: effect of past treatment history. Neurology 70 (2008) 54-65
    • (2008) Neurology , vol.70 , pp. 54-65
    • Schiller, Y.1    Najjar, Y.2
  • 20
    • 0026541738 scopus 로고    scopus 로고
    • Hauser WA. The natural history of drug resistant epilepsy: epidemiological considerations. In: Surgical treatment of epilepsy. Epilepsy Res 1992;(Suppl. 5):25-28.
    • Hauser WA. The natural history of drug resistant epilepsy: epidemiological considerations. In: Surgical treatment of epilepsy. Epilepsy Res 1992;(Suppl. 5):25-28.
  • 21
    • 33745686119 scopus 로고    scopus 로고
    • How long does it take for epilepsy to become intractable? A prospective investigation
    • Berg A.T., Vickrey B.G., Testa F.M., et al. How long does it take for epilepsy to become intractable? A prospective investigation. Ann Neurol 60 (2006) 73-79
    • (2006) Ann Neurol , vol.60 , pp. 73-79
    • Berg, A.T.1    Vickrey, B.G.2    Testa, F.M.3
  • 22
    • 47249105094 scopus 로고    scopus 로고
    • The prevalence of epilepsy and pharmacoresistant epilepsy in adults: a population-based study in a Western European country
    • Picot M.C., Baldy-Moulinier M., Daurès J.P., Dujols P., and Crespel A. The prevalence of epilepsy and pharmacoresistant epilepsy in adults: a population-based study in a Western European country. Epilepsia 49 (2008) 1230-1238
    • (2008) Epilepsia , vol.49 , pp. 1230-1238
    • Picot, M.C.1    Baldy-Moulinier, M.2    Daurès, J.P.3    Dujols, P.4    Crespel, A.5
  • 23
    • 66849131768 scopus 로고    scopus 로고
    • New developments in antiepileptic drug resistance: an integrative view
    • Schmidt D., and Löscher W. New developments in antiepileptic drug resistance: an integrative view. Epilepsy Curr 9 (2009) 47-52
    • (2009) Epilepsy Curr , vol.9 , pp. 47-52
    • Schmidt, D.1    Löscher, W.2
  • 24
    • 20544475805 scopus 로고    scopus 로고
    • Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms
    • Schmidt D., and Löscher W. Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms. Epilepsia 46 (2005) 858-877
    • (2005) Epilepsia , vol.46 , pp. 858-877
    • Schmidt, D.1    Löscher, W.2
  • 25
    • 33746887419 scopus 로고    scopus 로고
    • Experimental and clinical evidence for loss of effect (tolerance) during prolonged treatment with antiepileptic drugs, 1
    • Löscher W., and Schmidt D. Experimental and clinical evidence for loss of effect (tolerance) during prolonged treatment with antiepileptic drugs, 1. Epilepsia 47 (2006) 1253-1284
    • (2006) Epilepsia , vol.47 , pp. 1253-1284
    • Löscher, W.1    Schmidt, D.2
  • 26
    • 58149231251 scopus 로고    scopus 로고
    • The clinical impact of pharmacogenetics on the treatment of epilepsy
    • Löscher W., Klotz U., Zimprich F., and Schmidt D. The clinical impact of pharmacogenetics on the treatment of epilepsy. Epilepsia 50 (2009) 1-23
    • (2009) Epilepsia , vol.50 , pp. 1-23
    • Löscher, W.1    Klotz, U.2    Zimprich, F.3    Schmidt, D.4
  • 27
    • 0020608952 scopus 로고
    • Single drug therapy for intractable epilepsy
    • Schmidt D. Single drug therapy for intractable epilepsy. J Neurol 229 (1983) 221-226
    • (1983) J Neurol , vol.229 , pp. 221-226
    • Schmidt, D.1
  • 28
    • 20444407159 scopus 로고    scopus 로고
    • New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine
    • Rowan A.J., Ramsay R.E., Collins J.F., et al. New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. Neurology 64 (2005) 1868-1873
    • (2005) Neurology , vol.64 , pp. 1868-1873
    • Rowan, A.J.1    Ramsay, R.E.2    Collins, J.F.3
  • 29
    • 47249107324 scopus 로고    scopus 로고
    • Topiramate in older patients with partial-onset seizures: a pilot double-blind, dose-comparison study
    • Ramsay R.E., Uthman B., Pryor F.M., et al. Topiramate in older patients with partial-onset seizures: a pilot double-blind, dose-comparison study. Epilepsia 49 (2008) 1180-1185
    • (2008) Epilepsia , vol.49 , pp. 1180-1185
    • Ramsay, R.E.1    Uthman, B.2    Pryor, F.M.3
  • 30
    • 36349023589 scopus 로고    scopus 로고
    • Psychiatric comorbidity in epilepsy: a population-based analysis
    • Tellez-Centano J.F., Patten S.B., Jette N., et al. Psychiatric comorbidity in epilepsy: a population-based analysis. Epilepsia 48 (2007) 2336-2344
    • (2007) Epilepsia , vol.48 , pp. 2336-2344
    • Tellez-Centano, J.F.1    Patten, S.B.2    Jette, N.3
  • 31
    • 23844458228 scopus 로고    scopus 로고
    • Anxiety in patients with epilepsy: systematic review and suggestions for clinical management
    • Beyenburg S., Mitchell A.J., Schmidt D., Elger C.E., and Reuber M. Anxiety in patients with epilepsy: systematic review and suggestions for clinical management. Epilepsy Behav 7 (2005) 161-171
    • (2005) Epilepsy Behav , vol.7 , pp. 161-171
    • Beyenburg, S.1    Mitchell, A.J.2    Schmidt, D.3    Elger, C.E.4    Reuber, M.5
  • 32
    • 33646530956 scopus 로고    scopus 로고
    • Prognosis of seizure recurrence after stopping antiepileptic drugs in seizure-free patients: a long-term population-based study of childhood-onset epilepsy
    • Sillanpää M., and Schmidt D. Prognosis of seizure recurrence after stopping antiepileptic drugs in seizure-free patients: a long-term population-based study of childhood-onset epilepsy. Epilepsy Behav 8 (2006) 713-719
    • (2006) Epilepsy Behav , vol.8 , pp. 713-719
    • Sillanpää, M.1    Schmidt, D.2
  • 33
    • 0025760142 scopus 로고
    • Randomised study of antiepileptic drug withdrawal in patients in remission
    • Medical Research Council Antiepileptic Drug Withdrawal Study Group
    • Medical Research Council Antiepileptic Drug Withdrawal Study Group. Randomised study of antiepileptic drug withdrawal in patients in remission. Lancet 337 (1991) 1175-1180
    • (1991) Lancet , vol.337 , pp. 1175-1180
  • 34
    • 0028221118 scopus 로고
    • Relapse following discontinuation of antiepileptic drugs: a meta-analysis
    • Berg A.T., and Shinnar S. Relapse following discontinuation of antiepileptic drugs: a meta-analysis. Neurology 44 (1994) 601-608
    • (1994) Neurology , vol.44 , pp. 601-608
    • Berg, A.T.1    Shinnar, S.2
  • 35
    • 0021165055 scopus 로고
    • The late prognosis of epilepsy in childhood: results of a prospective follow-up study
    • Todt H. The late prognosis of epilepsy in childhood: results of a prospective follow-up study. Epilepsia 25 (1984) 137-144
    • (1984) Epilepsia , vol.25 , pp. 137-144
    • Todt, H.1
  • 36
    • 0028355367 scopus 로고
    • Discontinuing antiepileptic drugs in children with epilepsy: a comparison of a 6 week and a 9 month study period
    • Tennison M., Greenwood R., Lewis D., and Thorn M. Discontinuing antiepileptic drugs in children with epilepsy: a comparison of a 6 week and a 9 month study period. N Engl J Med 330 (1994) 1407-1410
    • (1994) N Engl J Med , vol.330 , pp. 1407-1410
    • Tennison, M.1    Greenwood, R.2    Lewis, D.3    Thorn, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.