A reverse vaccinology approach to swine dysentery vaccine development

Veterinary Microbiology

Volumn 137, Issue 1-2, 2009, Pages 111-119

  Song, Yong ^a   La, Tom ^a   Phillips, Nyree D ^a   Bellgard, Matthew I ^a   Hampson, David J ^a  

^a MURDOCH UNIVERSITY   (Australia)

Author keywords

Brachyspira hyodysenteriae; Recombinant protein; Reverse vaccinology; Spirochaete; Swine dysentery

Indexed keywords

ANTIBODY; BACTERIAL VACCINE; RECOMBINANT PROTEIN; RECOMBINANT VACCINE;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN ANTIBODY REACTION; ARTICLE; BACTERIAL CELL; BRACHYSPIRA HYODYSENTERIAE; COMPARATIVE STUDY; COMPUTER MODEL; CONTROLLED STUDY; DRUG EFFICACY; DYSENTERY; FEMALE; GENE SEQUENCE; GENETIC SCREENING; GENOMICS; INCIDENCE; INFECTION PREVENTION; MOLECULAR CLONING; MOUSE; NONHUMAN; OPEN READING FRAME; POLYMERASE CHAIN REACTION; SERUM; SWINE;

ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; BACTERIAL VACCINES; BRACHYSPIRA HYODYSENTERIAE; CLONING, MOLECULAR; COLON; DYSENTERY, BACILLARY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FECES; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; GRAM-NEGATIVE BACTERIAL INFECTIONS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; RECOMBINANT PROTEINS; SWINE; SWINE DISEASES;

BRACHYSPIRA HYODYSENTERIAE; MUS; SPIROCHAETA; SUIDAE;

EID: 67349113440     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetmic.2008.12.018     Document Type: Article

References (26)

1. Altschul S.F., Madden T.L., Schaffer A.A., Zhang J., Zhang Z., Miller W., and Lipman D.J. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25 (1997) 3389-3402
2. Bateman A., Birney E., Cerruti L., Durbin R., Etwiller L., Eddy S.R., Griffiths-Jones S., Howe K.L., Marshall M., and Sonnhammer E.L. The Pfam protein families database. Nucleic Acids Res. 30 (2002) 276-280
3. Bendtsen J.D., Nielsen H., von Heijne G., and Brunak S. Improved prediction of signal peptides: SignalP 3.0. J. Mol. Biol. 340 (2004) 783-795
4. Diarra A.T., Mittal K.R., and Achacha M. Evaluation of microagglutination test for differentiation between Serpulina (Treponema) hyodysenteriae and S. innocens and serotyping of S. hyodysenteriae. J. Clin. Microbiol. 32 (1994) 1976-1979
5. Duinhof T.F., Dierikx C.M., Koene M.G., van Bergen M.A., Mevius D.J., Veldman K.T., van Beers-Schreurs H.M., and de Winne R.T. Multiresistant Brachyspira hyodysenteriae in a Dutch sow herd. Tijdschr. Diergeneeskd. 133 (2008) 604-608
6. Ewing B., Hillier L., Wendl M.C., and Green P. Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res. 8 (1998) 175-185
7. Gabe J.D., Chang R.J., Slomiany R., Andrews W.H., and McCaman M.T. Isolation of extracytoplasmic proteins from Serpulina hyodysenteriae B204 and molecular cloning of the flaB1 gene encoding a 38-kilodalton flagellar protein. Infect. Immun. 63 (1995) 142-148
8. Gardy J.L., Laird M.R., Chen F., Rey S., Walsh C.J., Ester M., and Brinkman F.S. PSORTb v.2. 0: expanded prediction of bacterial protein subcellular localization and insights gained from comparative proteome analysis. Bioinformatics 21 (2005) 617-623
9. Gordon D., Abajian C., and Green P. Consed: a graphical tool for sequence finishing. Genome Res. 8 (1998) 195-202
10. Hampson D.J., Fellström C., and Thomson J.R. Swine dysentery. In: Straw B.E., Zimmerman J.J., D'Allaire S., and Taylor D.J. (Eds). Diseases of Swine (2006), Blackwell Publishing, Oxford, UK 785-805 (Chapter 48)
11. Hofmann K., Bucher P., Falquet L., and Bairoch A. The PROSITE database, its status in 1999. Nucleic Acids Res. 27 (1999) 215219
12. Kunkle R.A., Harris D.L., and Kinyon J.M. Autoclaved liquid medium for propagation of Treponema hyodysenteriae. J. Clin. Microbiol. 24 (1986) 669-671
13. La T., Phillips N.D., and Hampson D.J. Development of a duplex PCR assay for detection of Brachyspira hyodysenteriae and Brachyspira pilosicoli in pig feces. J. Clin. Microbiol. 41 (2003) 3372-3375
14. La T., Phillips N.D., Reichel M.P., and Hampson D.J. Protection of pigs from swine dysentery by vaccination with recombinant BmpB, a 29.7 kDa outer-membrane lipoprotein of Brachyspira hyodysenteriae. Vet. Microbiol. 102 (2004) 97-109
15. Lukashin A.V., and Borodovsky M. GeneMark.hmm: new solutions for gene finding. Nucleic Acids Res. 26 (1998) 1107-1115
16. Movahedi A., and Hampson D.J. New ways to identify novel bacterial antigens for vaccine development. Vet. Microbiol. 131 (2008) 1-13
17. Nakai K. Protein sorting signals and prediction of subcellular localization. Adv. Protein Chem. 54 (2000) 277-344
18. Pizza M., Scarlato V., Masignani V., Giuliani M.M., Arico B., Comanducci M., et al. Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. Science 287 (2000) 1816-1820
19. Rappuoli R. Reverse vaccinology, a genome-based approach to vaccine development. Vaccine 19 (2001) 2688-2691
20. Rees A.S., Lysons R.J., Stokes C.R., and Bourne F.J. Antibody production by the pig colon during infection with Treponema hyodysenteriae. Res. Vet. Sci. 47 (1989) 263-269
21. Salzberg S.L., Pertea M., Delcher A.L., Gardner M.J., and Tettelin H. Interpolated Markov models for eukaryotic gene finding. Genomics 59 (1999) 24-31
22. Setubal J.C., Reis M., Matsunaga J., and Haake D.A. Lipoprotein computational prediction in spirochaetal genomes. Microbiology 152 (2006) 113-121
23. Tappero J.W., Lagos R., Ballesteros A.M., Plikaytis B., Williams D., Dykes J., et al. Immunogenicity of 2 serogroup B outer-membrane protein meningococcal vaccines: a randomized controlled trial in Chile. JAMA 281 (1999) 1520-1527
24. Thompson J.D., Higgins D.G., and Gibson T.J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22 (1994) 4673-4680
25. Wannemuehler M.J., Hubbard R.D., and Greer J.M. Characterization of the major outer membrane antigens of Treponema hyodysenteriae. Infect. Immun. 56 (1988) 3032-3039
26. Wheeler D.L., Church D.M., Lash A.E., Leipe D.D., Madden T.L., Pontius J.U., Schuler G.D., Schriml L.M., Tatusova T.A., Wagner L., and Rapp B.A. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 29 (2001) 11-16