메뉴 건너뛰기




Volumn 4, Issue 2, 2009, Pages 204-213

On the benefits of silymarin in murine colitis by improving balance of destructive cytokines and reduction of toxic stress in the bowel cells

Author keywords

Inflammatory bowel disease; Inflammatory cytokines; Malondialdehyde; Myeloperoxidase; Silymarin

Indexed keywords

ANIMALIA; MURINAE; RATTUS;

EID: 67349111659     PISSN: 1895104X     EISSN: 16443632     Source Type: Journal    
DOI: 10.2478/s11535-008-0053-2     Document Type: Article
Times cited : (42)

References (53)
  • 1
    • 55249110001 scopus 로고    scopus 로고
    • Potassium channel openers and improvement of toxic stress: Do they have role in the management of inflammatory bowel disease?
    • A. Hosseini-Tabatabaei M. Abdollahi 2008 Potassium channel openers and improvement of toxic stress: Do they have role in the management of inflammatory bowel disease? Inflamm. Allergy Drug Targets 7 129 135
    • (2008) Inflamm. Allergy Drug Targets , vol.7 , pp. 129-135
    • Hosseini-Tabatabaei, A.1    Abdollahi, M.2
  • 3
    • 85047688069 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Progress and current concepts of etiopathogenesis
    • F. Scaldaferri C. Fiocchi 2007 Inflammatory bowel disease: progress and current concepts of etiopathogenesis J. Dig. Dis. 8 171 178
    • (2007) J. Dig. Dis. , vol.8 , pp. 171-178
    • Scaldaferri, F.1    Fiocchi, C.2
  • 4
    • 34547851729 scopus 로고    scopus 로고
    • Oxidative stress and pathogenesis of inflammatory bowel disease: An epiphenomenon or the cause?
    • DOI 10.1007/s10620-006-9622-2
    • A. Rezaie R.D. Parker M. Abdollahi 2007 Oxidative stress and pathogenesis of inflammatory bowel disease: an epiphenomenon or the cause? Dig. Dis. Sci. 52 2015 2021 (Pubitemid 47246507)
    • (2007) Digestive Diseases and Sciences , vol.52 , Issue.9 , pp. 2015-2021
    • Rezaie, A.1    Parker, R.D.2    Abdollahi, M.3
  • 5
    • 0037237973 scopus 로고    scopus 로고
    • Antioxidants, oxidative damage and oxygen deprivation stress: A review
    • DOI 10.1093/aob/mcf118
    • O. Blokhina E. Virolainen K.V. Fagerstedt 2003 Antioxidants, oxidative damage and oxygen deprivation stress: a review Ann. Bot. (Lond.) 91 179 194 (Pubitemid 36117177)
    • (2003) Annals of Botany , vol.91 , Issue.SPEC. ISS. JAN. , pp. 179-194
    • Blokhina, O.1    Virolainen, E.2    Fagerstedt, K.V.3
  • 6
    • 0034937590 scopus 로고    scopus 로고
    • Cytotoxicity related to oxidative and nitrosative stress by nitric oxide
    • D.A. Wink K.M. Miranda M.G. Espey 2001 Cytotoxicity related to oxidative and nitrosative stress by nitric oxide Exp. Biol. Med. 226 621 623 (Pubitemid 32619597)
    • (2001) Experimental Biology and Medicine , vol.226 , Issue.7 , pp. 621-623
    • Wink, D.A.1    Miranda, K.M.2    Espey, M.G.3
  • 7
    • 2342445762 scopus 로고    scopus 로고
    • Management of inflammatory bowel disease
    • DOI 10.1136/pgmj.2003.013722
    • M. Nayar J.M. Rhodes 2004 Management of inflammatory bowel disease Postgrad. Med. J. 80 206 213 (Pubitemid 38561400)
    • (2004) Postgraduate Medical Journal , vol.80 , Issue.942 , pp. 206-213
    • Nayar, M.1    Rhodes, J.M.2
  • 8
    • 33644918277 scopus 로고    scopus 로고
    • Review article: Complementary and alternative therapies for inflammatory bowel disease
    • DOI 10.1111/j.1365-2036.2006.02761.x
    • L. Langmead D.S. Rampton 2006 Review article: complementary and alternative therapies for inflammatory bowel disease, Aliment Pharmacol. Ther. 23 341 349 (Pubitemid 43382014)
    • (2006) Alimentary Pharmacology and Therapeutics , vol.23 , Issue.3 , pp. 341-349
    • Langmead, L.1    Rampton, D.S.2
  • 9
    • 7944233392 scopus 로고    scopus 로고
    • Targeting therapy in pediatric inflammatory bowel disease
    • M.C. Dubinsky 2004 Targeting therapy in pediatric inflammatory bowel disease Curr. Treat Options Gastroenterol. 7 391 405 (Pubitemid 39467909)
    • (2004) Current Treatment Options in Gastroenterology , vol.7 , Issue.5 , pp. 391-405
    • Dubinsky, M.C.1
  • 12
    • 41949134736 scopus 로고    scopus 로고
    • On the benefit of probiotics in the management of pouchitis in patients underwent ileal pouch anal anastomosis: A meta-analysis of controlled clinical trials
    • B. Elahi S. Nikfar S. Derakhshani M. Vafaie M. Abdollahi 2007 On the benefit of probiotics in the management of pouchitis in patients underwent ileal pouch anal anastomosis: A meta-analysis of controlled clinical trials Dig. Dis. Sci. 53 1278 1284
    • (2007) Dig. Dis. Sci. , vol.53 , pp. 1278-1284
    • Elahi, B.1    Nikfar, S.2    Derakhshani, S.3    Vafaie, M.4    Abdollahi, M.5
  • 14
    • 48249089620 scopus 로고    scopus 로고
    • A metaanalysis of the benefit of probiotics in maintaining remission of human ulcerative colitis: Evidence for prevention of disease relapse and maintenance of remission
    • R. Rahimi S. Nikfar A. Rezaie M. Abdollahi 2008 A metaanalysis of the benefit of probiotics in maintaining remission of human ulcerative colitis: evidence for prevention of disease relapse and maintenance of remission Arch. Med. Sci. 4 185 190
    • (2008) Arch. Med. Sci. , vol.4 , pp. 185-190
    • Rahimi, R.1    Nikfar, S.2    Rezaie, A.3    Abdollahi, M.4
  • 15
    • 50249087428 scopus 로고    scopus 로고
    • A meta-analysis on the efficacy of probiotics for maintenance of remission and prevention of clinical and endoscopic relapse in Crohn's disease
    • R. Rahimi S. Nikfar F. Rahimi 2008 A meta-analysis on the efficacy of probiotics for maintenance of remission and prevention of clinical and endoscopic relapse in Crohn's disease Dig. Dis. Sci. 53 2524 2531
    • (2008) Dig. Dis. Sci. , vol.53 , pp. 2524-2531
    • Rahimi, R.1    Nikfar, S.2    Rahimi, F.3
  • 16
    • 34848872854 scopus 로고    scopus 로고
    • A meta-analysis of antibiotic therapy for active ulcerative colitis
    • DOI 10.1007/s10620-007-9760-1
    • R. Rahimi S. Nikfar A. Rezaie M. Abdollahi 2007 A metaanalysis of antibiotic therapy for active ulcerative colitis Dig. Dis. Sci. 52 2920 2925 (Pubitemid 47512546)
    • (2007) Digestive Diseases and Sciences , vol.52 , Issue.11 , pp. 2920-2925
    • Rahimi, R.1    Nikfar, S.2    Rezaie, A.3    Abdollahi, M.4
  • 17
    • 33846798073 scopus 로고    scopus 로고
    • A meta-analysis of broad-spectrum antibiotic therapy in patients with active Crohn's disease
    • DOI 10.1016/j.clinthera.2006.12.012, PII S0149291806003158
    • R. Rahimi S. Nikfar A. Rezaie M. Abdollahi 2006 A meta-analysis of broad spectrum antibiotic therapy in patients with active Crohn's disease Clin. Ther. 28 1983 1988 (Pubitemid 46215747)
    • (2006) Clinical Therapeutics , vol.28 , Issue.12 , pp. 1983-1988
    • Rahimi, R.1    Nikfar, S.2    Rezaie, A.3    Abdollahi, M.4
  • 18
    • 67349188746 scopus 로고    scopus 로고
    • A meta-analysis of the efficacy of sulfasalazine in comparison with 5-aminosalicylates in the induction of improvement and maintenance of remission in patients with ulcerative colitis
    • [Epub ahead of print], DOI: 10.1007/s10620-008-0481-x
    • Nikfar S., Rahimi R., Rezaie A., Abdollahi M., A meta-analysis of the efficacy of sulfasalazine in comparison with 5-aminosalicylates in the induction of improvement and maintenance of remission in patients with ulcerative colitis, Dig. Dis. Sci., 2008 [Epub ahead of print], DOI: 10.1007/s10620-008- 0481-x
    • Dig. Dis. Sci., 2008
    • Nikfar, S.1    Rahimi, R.2    Rezaie, A.3    Abdollahi, M.4
  • 20
    • 39749151003 scopus 로고    scopus 로고
    • Pregnancy outcome in women with inflammatory bowel disease following exposure to 5-aminosalicylic acid drugs: A meta-analysis
    • R. Rahimi S. Nikfar A. Rezaie M. Abdollahi 2008 Pregnancy outcome in women with inflammatory bowel disease following exposure to 5-aminosalicylic acid drugs: a meta-analysis Reprod. Toxicol. 25 271 275
    • (2008) Reprod. Toxicol. , vol.25 , pp. 271-275
    • Rahimi, R.1    Nikfar, S.2    Rezaie, A.3    Abdollahi, M.4
  • 24
    • 59449103434 scopus 로고    scopus 로고
    • On the use of herbal medicines in management of inflammatory bowel diseases: A systematic review of animal and human studies
    • [Epub ahead of print], DOI: 10.1007/s10620-008-0368-x
    • Rahimi R., Mozaffari S., Abdollahi M., On the use of herbal medicines in management of inflammatory bowel diseases: A systematic review of animal and human studies, Dig. Dis. Sci., 2008 [Epub ahead of print], DOI: 10.1007/s10620-008-0368-x
    • (2008) Dig. Dis. Sci.
    • Rahimi, R.1    Mozaffari, S.2    Abdollahi, M.3
  • 25
    • 33846519345 scopus 로고    scopus 로고
    • Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine
    • S.C. Pradhan C. Girish 2006 Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine Indian. J. Med. Res. 124 491 504 (Pubitemid 46157708)
    • (2006) Indian Journal of Medical Research , vol.124 , pp. 491-504
    • Pradhan, S.C.1    Girish, C.2
  • 26
    • 40149102006 scopus 로고    scopus 로고
    • Silymarin, the antioxidant component of Silybum marianum, prevents sepsis-induced acute lung and brain injury
    • H.Z. Toklu T. Tunali Akbay A. Velioglu-Ogunc F. Ercan N. Gedik M. Keyer-Uysal 2008 Silymarin, the antioxidant component of Silybum marianum, prevents sepsis-induced acute lung and brain injury J. Surg. Res. 145 214 222
    • (2008) J. Surg. Res. , vol.145 , pp. 214-222
    • Toklu, H.Z.1    Tunali Akbay, T.2    Velioglu-Ogunc, A.3    Ercan, F.4    Gedik, N.5    Keyer-Uysal, M.6
  • 27
    • 27744474094 scopus 로고    scopus 로고
    • Milk thistle
    • F. Rainone 2005 Milk thistle Am. Fam. Physician. 72 1285 1288 (Pubitemid 43104260)
    • (2005) American Family Physician , vol.72 , Issue.7 , pp. 1285-1288
    • Rainone, F.1
  • 28
    • 33847265733 scopus 로고    scopus 로고
    • Silybin and silymarin - New and emerging applications in medicine
    • DOI 10.2174/092986707779941159
    • R. Gazák D. Walterová V. Kren 2007 Silybin and silymarin-new and emerging applications in medicine Curr. Med. Chem. 14 315 338 (Pubitemid 46313027)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.3 , pp. 315-338
    • Gazak, R.1    Walterova, D.2    Kren, V.3
  • 29
    • 0032239998 scopus 로고    scopus 로고
    • A Review of Plants Used in the Treatment of Liver Disease: Part 1
    • S. Luper 1998 A review of plants used in the treatment of liver disease: part 1 Altern. Med. Rev. 3 410 421 (Pubitemid 128709687)
    • (1998) Alternative Medicine Review , vol.3 , Issue.6 , pp. 410-421
    • Luper, S.1
  • 30
    • 0344687228 scopus 로고    scopus 로고
    • Protection against lipopolysaccharide-induced sepsis and inhibition of interleukin-1 and prostaglandin E2 synthesis by silymarin
    • DOI 10.1016/j.bcp.2003.08.032
    • J.S. Kang Y.J. Jeon S.K. Park K.H. Yang H.M. Kim 2004 Protection against lipopolysaccharide-induced sepsis and inhibition of interleukin-1beta and prostaglandin E2 synthesis by silymarin Biochem. Pharmacol. 67 175 181 (Pubitemid 37518545)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.1 , pp. 175-181
    • Kang, J.S.1    Jeon, Y.J.2    Park, S.-K.3    Yang, K.-H.4    Kim, H.M.5
  • 32
    • 0036085857 scopus 로고    scopus 로고
    • Inhibition of inducible nitric-oxide synthase expression by silymarin in lipopolysaccharide-stimulated macrophages
    • DOI 10.1124/jpet.302.1.138
    • J.S. Kang Y.J. Jeon H.M. Kim S.H. Han K.H. Yang 2002 Inhibition of inducible nitric-oxide synthase expression by silymarin in lipopolysaccharidestimulated macrophages J. Pharmacol. Exp. Ther. 302 138 144 (Pubitemid 34680431)
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.302 , Issue.1 , pp. 138-144
    • Kang, J.S.1    Jeon, Y.J.2    Kim, H.M.3    Han, S.H.4    Yang, K.-H.5
  • 33
    • 0035035418 scopus 로고    scopus 로고
    • Role of nitric oxide in gastrointestinal inflammatory and ulcerative diseases: Perspective for drugs development
    • DOI 10.2174/1381612013398491
    • M.D. Barrachina J. Panés J.V. Esplugues 2001 Role of nitric oxide in gastrointestinal inflammatory and ulcerative diseases: perspective for drugs development Curr. Pharm. Des. 7 31 48 (Pubitemid 32409706)
    • (2001) Current Pharmaceutical Design , vol.7 , Issue.1 , pp. 31-48
    • Barrachina, M.D.1    Panes, J.2    Esplugues, J.V.3
  • 34
    • 13644265626 scopus 로고    scopus 로고
    • Alterations in antioxidant power and levels of epidermal growth factor and nitric oxide in saliva of patients with inflammatory bowel diseases
    • DOI 10.1007/s10620-004-9564-5
    • G. Jahanshahi V. Motavasel A. Rezaie A.A. Hashtroudi N.E. Daryani M. Abdollahi 2004 Alterations in antioxidant power and levels of epidermal growth factor and nitric oxide in saliva of patients with inflammatory bowel diseases Dig. Dis. Sci. 49 1752 1757 (Pubitemid 40228532)
    • (2004) Digestive Diseases and Sciences , vol.49 , Issue.11-12 , pp. 1752-1757
    • Jahanshahi, G.1    Motavasel, V.2    Rezaie, A.3    Hashtroudi, A.A.4    Daryani, N.E.5    Abdollahi, M.6
  • 35
    • 0032715311 scopus 로고    scopus 로고
    • Silymarin suppresses TNF-induced activation of NF-kappa B, c-Jun N-terminal kinase, and apoptosis
    • S.K. Manna A. Mukhopadhyay N.T. Van B.B. Aggarwal 1999 Silymarin suppresses TNF-induced activation of NF-kappa B, c-Jun N-terminal kinase, and apoptosis J. Immunol. 163 6800 6809
    • (1999) J. Immunol. , vol.163 , pp. 6800-6809
    • Manna, S.K.1    Mukhopadhyay, A.2    Van N., T.3    Aggarwal, B.B.4
  • 36
    • 43049118972 scopus 로고    scopus 로고
    • Silymarin in the treatment of patients with primary sclerosing cholangitis: An open-label pilot study
    • P. Angulo R.A. Jorgensen K.V. Kowdley K.D. Lindor 2008 Silymarin in the treatment of patients with primary sclerosing cholangitis: an open-label pilot study Dig. Dis. Sci. 53 1716 1720
    • (2008) Dig. Dis. Sci. , vol.53 , pp. 1716-1720
    • Angulo, P.1    Jorgensen, R.A.2    Kowdley, K.V.3    Lindor, K.D.4
  • 37
    • 0035211762 scopus 로고    scopus 로고
    • The use of silymarin in the treatment of liver diseases
    • R. Saller R. Meier R. Brignoli 2001 The use of silymarin in the treatment of liver diseases. Drugs 61 2035 2063 (Pubitemid 33135182)
    • (2001) Drugs , vol.61 , Issue.14 , pp. 2035-2063
    • Saller, R.1    Meier, R.2    Brignoli, R.3
  • 38
    • 0031941021 scopus 로고    scopus 로고
    • Effects of rubidium on the secretory function of the rat submandibular gland
    • DOI 10.1080/107691898229369
    • M. Abdollahi A.R. Dehpour G. Baharnouri 1998 Alteration by rubidium of rat submandibular secretion of protein and N-acetyl -D-glucosaminidase Toxic. Subst. Mech. 17 121 131 (Pubitemid 28180816)
    • (1998) Toxic Substance Mechanisms , vol.17 , Issue.2 , pp. 121-131
    • Abdollahi, M.1    Dehpour, A.2    Baharnouri, G.3
  • 39
    • 0026556835 scopus 로고
    • Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis
    • J.L. Wallace C.M. Keenan D. Gale T.S. Shoupe 1992 Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis Gastroenterology 102 18 27
    • (1992) Gastroenterology , vol.102 , pp. 18-27
    • Wallace, J.L.1    Keenan, C.M.2    Gale, D.3    Shoupe, T.S.4
  • 40
    • 36248939201 scopus 로고    scopus 로고
    • Antioxidant potential of various extracts from Ferula szovitsiana in relation to their phenolic content
    • DOI 10.1080/13880200701575098, PII 783773215
    • G. Dehghan A. Shafiee M.H. Ghahremani S.K. Ardestani M. Abdollahi 2007 Antioxidant potential of various extracts from ferula szovitsiana in relation to their phenolic content, Pharm Biol.. 45 691 699 (Pubitemid 350125760)
    • (2007) Pharmaceutical Biology , vol.45 , Issue.9 , pp. 691-699
    • Dehghan, G.1    Shafiee, A.2    Ghahremani, M.H.3    Ardestani, S.K.4    Abdollahi, M.5
  • 41
    • 20444388662 scopus 로고    scopus 로고
    • Total antioxidant capacity and levels of epidermal growth factor and nitric oxide in blood and saliva of insulin-dependent diabetic patients
    • DOI 10.1016/j.arcmed.2005.03.007, PII S0188440905000494
    • F. Astaneie M. Afshari A. Mojtahedi S. Mostafalou M.J. Zamani B. Larijani 2005 Total antioxidant capacity and levels of epidermal growth factor and nitric oxide in blood and saliva of insulin-dependent diabetic patients Arch. Med. Res. 36 376 381 (Pubitemid 40798392)
    • (2005) Archives of Medical Research , vol.36 , Issue.4 , pp. 376-381
    • Astaneie, F.1    Afshari, M.2    Mojtahedi, A.3    Mostafalou, S.4    Zamani, M.J.5    Larijani, B.6    Abdollahi, M.7
  • 44
    • 34948894959 scopus 로고    scopus 로고
    • -Lipoic acid modulates gut inflammation induced by trinitrobenzene sulfonic acid in rats
    • DOI 10.1111/j.1440-1746.2006.04504.x
    • M. Kolgazi N. Jahovic M. Yüksel F. Ercan I. Alican 2007 α-lipoic acid modulates gut inflammation induced by trinitrobenzene sulfonic acid in rats J. Gastroenterol. Hepatol. 22 1859 1865 (Pubitemid 47525046)
    • (2007) Journal of Gastroenterology and Hepatology , vol.22 , Issue.11 , pp. 1859-1865
    • Kolgazi, M.1    Jahovic, N.2    Yuksel, M.3    Ercan, F.4    Alican, I.5
  • 47
    • 33846564412 scopus 로고    scopus 로고
    • Do anti-tumor necrosis factors induce response and remission in patients with acute refractory Crohn's disease? A systematic meta-analysis of controlled clinical trials
    • DOI 10.1016/j.biopha.2006.06.022, PII S0753332206003301
    • R. Rahimi S. Nikfar M. Abdollahi 2007 Do anti-tumor necrosis factors induce response and remission in patients with acute refractory Crohn's disease? A systematic meta-analysis of controlled clinical trials Biomed. Pharmacother. 61 75 80 (Pubitemid 46185874)
    • (2007) Biomedicine and Pharmacotherapy , vol.61 , Issue.1 , pp. 75-80
    • Rahimi, R.1    Nikfar, S.2    Abdollahi, M.3
  • 48
    • 34447115672 scopus 로고    scopus 로고
    • Meta-analysis technique confirms the effectiveness of anti-TNF- in the management of active ulcerative colitis when administered in combination with corticosteroids
    • R. Rahimi S. Nikfar M. Abdollahi 2007 Meta-analysis technique confirms the effectiveness of anti-TNF-alpha in the management of active ulcerative colitis when administered in combination with corticosteroids Med. Sci. Monit. 13 PI13 PI18 (Pubitemid 47037680)
    • (2007) Medical Science Monitor , vol.13 , Issue.7
    • Rahimi, R.1    Nikfar, S.2    Abdollahi, M.3
  • 49
    • 0027272186 scopus 로고
    • Inflammatory bowel disease - A radical view
    • N.J. Simmonds D.S. Rampton 1993 Inflammatory bowel disease - a radical view Gut 34 865 868 (Pubitemid 23203102)
    • (1993) Gut , vol.34 , Issue.7 , pp. 865-868
    • Simmonds, N.J.1    Rampton, D.S.2
  • 50
    • 0031914778 scopus 로고    scopus 로고
    • Cytokines in inflammatory bowel disease
    • DOI 10.1007/s002689900401
    • G. Rogler T. Andus 1998 Cytokines in inflammatory bowel disease World J. Surg. 22 382 389 (Pubitemid 28113526)
    • (1998) World Journal of Surgery , vol.22 , Issue.4 , pp. 382-389
    • Rogler, G.1    Andus, T.2
  • 52
    • 0141626704 scopus 로고    scopus 로고
    • Intestinal oxidative damage in inflammatory bowel disease: Semi-quantification, localization, and association with mucosal antioxidants
    • DOI 10.1002/path.1409
    • L. Kruidenier I. Kuiper C.B. Lamers H.W. Verspaget 2003 Intestinal oxidative damage in inflammatory bowel disease: semi-quantification, localization, and association with mucosal antioxidants J. Pathol. 201 28 36 (Pubitemid 37121200)
    • (2003) Journal of Pathology , vol.201 , Issue.1 , pp. 28-36
    • Kruidenier, L.1    Kuiper, I.2    Lamers, C.B.H.W.3    Verspaget, H.W.4
  • 53
    • 0035105489 scopus 로고    scopus 로고
    • Effects of Silymarin on the acute stage of the trinitrobenzenesulphonic acid model of rat colitis
    • DOI 10.1055/s-2001-10620
    • T. Cruz J. Gμlvez E. Crespo M.A. Ocete A. Zarzuelo 2001 Effects of silymarin on the acute stage of the trinitrobenzenesulphonic acid model of rat colitis Planta Med. 67 94 96 (Pubitemid 32199958)
    • (2001) Planta Medica , vol.67 , Issue.1 , pp. 94-96
    • Cruz, T.1    Galvez, J.2    Crespo, E.3    Ocete, M.A.4    Zarzuelo, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.