Methodological study investigating long term laser Doppler measured cerebral blood flow changes in a permanently occluded rat stroke model

Journal of Neuroscience Methods

Volumn 180, Issue 1, 2009, Pages 52-56

  Eve, David J ^a   Musso III, James ^a   Park, Dong Hyuk ^a   Oliveira, Cathy ^b   Pollock, Kenny ^b   Hope, Andrew ^b   Baradez, Marc Olivier ^b   Sinden, John D ^b   Sanberg, Paul R ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b RENEURON LTD   (United Kingdom)

Author keywords

Cell transplantation; Cerebral blood flow; Laser Doppler; Middle cerebral artery occlusion; Stroke

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; CONTROLLED STUDY; EXPERIMENTAL STUDY; FUNCTION TEST; LASER DOPPLER FLOWMETRY; MALE; METHODOLOGY; MIDDLE CEREBRAL ARTERY OCCLUSION; MONITORING; NEURAL STEM CELL; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; RAT; SHAM PROCEDURE; SPRAGUE DAWLEY RAT; STROKE;

ANIMALS; BIOLOGICAL CLOCKS; CEREBRAL ARTERIES; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; FUNCTIONAL LATERALITY; GRAFT SURVIVAL; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; LASER-DOPPLER FLOWMETRY; MALE; OPTICS AND PHOTONICS; PREDICTIVE VALUE OF TESTS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SENSITIVITY AND SPECIFICITY; STEM CELL TRANSPLANTATION; STEM CELLS; STROKE; TREATMENT OUTCOME;

EID: 67349103402     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2009.02.016     Document Type: Article

References (25)

1. Borlongan C.V., Lind J.G., Dillon-Carter O., Yu G., Hadman M., Cheng C., Carroll J., and Hess D.C. Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats. Brain Res 1010 (2004) 108-116
2. Chen Y., Ito A., Takai K., and Saito N. Blocking pterygopalatine arterial blood flow decreases infarct volume variability in a mouse model of intraluminal suture middle cerebral artery occlusion. J Neurosci Methods 174 (2008) 18-24
3. Eve D.J., Musso III J., Bui V.H., Smith A.J., Gemma C., Cameron D.F., Oliveira C., Pollock K., Hope A., Baradez M.-O., Sinden J.D., and Sanberg P.R. Release of VEGF by ReN001 cortical stem cells. Cell Transplant 17 (2008) 464-465
4. Gu W., Jiang W., and Wester P. Real-time cortical cerebral blood flow follow-up in conscious, freely moving rats by laser Doppler flowmetry. Methods 30 (2003) 172-177
5. Gulbenkian S., Uddman R., and Edvinsson L. Neuronal messengers in the human cerebral circulation. Peptides 22 (2001) 995-1007
6. Harada H., Wang Y., Mishima Y., Uehara N., Makaya T., and Kano T. A novel method of detecting rCBF with laser-Doppler flowmetry without cranial window through the skull for a MCAO rat model. Brain Res Brain Res Protoc 14 (2005) 165-170
7. Hodges H., Pollock K., Stroemer P., Patel S., Stevanato L., Reuter I., and Sinden J. Making stem cell lines suitable for transplantation. Cell Transplant 16 (2007) 101-115
8. Hungerhuber E., Zausinger S., Westermaier T., Plesnila N., and Schmid-Elsaesser R. Simultaneous bilateral laser Doppler fluxmetry and electrophysiological recording during middle cerebral artery occlusion in rats. J Neurosci Methods 154 (2006) 109-115
9. Iadecola C., and Nedergaard M. Glial regulation of the cerebral microvasculature. Nat Neurosci 10 (2007) 1369-1376
10. Kaufman J.A., Phillips-Conroy J.E., Black K.J., and Perlmutter J.S. Asymmetric regional cerebral blood flow in sedated baboons measured by positron emission tomography (PET). Am J Phys Anthropol 121 (2003) 369-377
11. Kim D., Chun B.G., Kim Y.K., Lee Y.H., Park C.S., Jeon I., Cheong C., Hwang T.S., Chung H., Gwag B.J., Hong K.S., and Song J. In vivo tracking of human mesenchymal stem cells in experimental stroke. Cell Transplant 16 (2007) 1007-1012
12. Kozak W., Kozak A., Johnson M.H., Elewa H.F., and Fagan S.C. Vascular protection with candesartan after experimental acute stroke in hypertensive rats: a dose-response study. J Pharmacol Exp Ther 326 (2008) 773-782
13. Li Y., Lu Z., Keogh C.L., Yu S.P., and Wei L. Erythropoietin-induced neurovascular protection, angiogenesis, and cerebral blood flow restoration after focal ischemia in mice. J Cereb Blood Flow Metab 27 (2007) 1043-1054
14. Longa E.Z., Weinstein P.R., Carlson S., and Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20 (1989) 84-91
15. Mathe Z., Dupraz P., Rinsch C., Thorens B., Bosco D., Zbinden M., Morel P., Berney T., and Pepper M.S. Tetracycline-regulated expression of VEGF-A in beta cells induces angiogenesis: improvement of engraftment following transplantation. Cell Transplant 15 (2006) 621-636
16. Newcomb J.D., Ajmo Jr. C.T., Sanberg C.D., Sanberg P.R., Pennypacker K.R., and Willing A.E. Timing of cord blood treatment after experimental stroke determines therapeutic efficacy. Cell Transplant 15 (2006) 213-223
17. Perlmutter J.S., Powers W.J., Herscovitch P., Fox P.T., and Raichle M.E. Regional asymmetries of cerebral blood flow, blood volume, and oxygen utilization and extraction in normal subjects. J Cereb Blood Flow Metab 7 (1987) 64-67
18. Pollock K., Stroemer P., Patel S., Stevanato L., Hope A., Miljan E., Dong Z., Hodges H., Price J., and Sinden J.D. A conditionally immortal clonal stem cell line from human cortical neuroepithelium for the treatment of ischemic stroke. Exp Neurol 199 (2006) 143-155
19. Rivera F., Costa G., Abin A., Urbanavicius J., Arruti C., Casanova G., and Dajas F. Reduction of ischemic brain damage and increase of glutathione by a liposomal preparation of quercetin in permanent focal ischemia in rats. Neurotox Res 13 (2008) 105-114
20. Scholler K., Zausinger S., Baethmann A., and Schmid-Elsaesser R. Neuroprotection in ischemic stroke-combination drug therapy and mild hypothermia in a rat model of permanent focal cerebral ischemia. Brain Res 1023 (2004) 272-278
21. Soehle M., Heimann A., and Kempski O. On the number of measurement sites required to assess regional cerebral blood flow by laser-Doppler scanning during cerebral ischemia and reperfusion. J Neurosci Methods 110 (2001) 91-94
22. Ulrich P.T., Kroppenstedt S., Heimann A., and Kempski O. Laser-Doppler scanning of local cerebral blood flow and reserve capacity and testing of motor and memory functions in a chronic 2-vessel occlusion model in rats. Stroke 29 (1998) 2412-2420
23. Wegener S., and Wong E.C. Longitudinal MRI studies in the isoflurane-anesthetized rat: long-term effects of a short hypoxic episode on regulation of cerebral blood flow as assessed by pulsed arterial spin labelling. NMR Biomed 21 (2008) 696-703
24. Wu J., Sun Z., Sun H.S., Wu J., Weisel R.D., Keating A., Li Z.H., Feng Z.P., and Li R.K. Intravenously administered bone marrow cells migrate to damaged brain tissue and improve neural function in ischemic rats. Cell Transplant 16 (2007) 993-1005
25. Xiao B., Bi F.F., Hu Y.Q., Tian F.F., Wu Z.G., Mujlli H.M., Ding L., and Zhou X.F. Edaravone neuroprotection effected by suppressing the gene expression of the Fas signal pathway following transient focal ischemia in rats. Neurotox Res 12 (2007) 155-162