Kinetics of 8-2 fluorotelomer alcohol and its metabolites, and liver glutathione status following daily oral dosing for 45 days in male and female rats

Chemico-Biological Interactions

Volumn 180, Issue 2, 2009, Pages 281-295

  Fasano, William J ^a   Sweeney, Lisa M ^b   Mawn, Michael P ^a   Nabb, Diane L ^a   Szostek, Bogdan ^a   Buck, Robert C ^a   Gargas, Michael L ^b  

^a DUPONT COMPANY   (United States)

^b Sapphire Group   (United States)

Author keywords

8 2 Fluorotelomer alcohol; Cysteine conjugated lyase; Glutathione; Mode of action; Perfluorinated and polyfluorinated acids; Perfluorooctanoic acid

Indexed keywords

8,2 FLUOROTELOMER ALCOHOL; ACETYLCYSTEINE; ALCOHOL DERIVATIVE; GLUTATHIONE; PERFLUORO COMPOUND; PERFLUOROOCTANOIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD LEVEL; BODY WEIGHT; CONTROLLED STUDY; FEMALE; KIDNEY CLEARANCE; LIVER TOXICITY; LONG TERM EXPOSURE; MALE; NONHUMAN; RAT; SEX DIFFERENCE;

ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROCARBONS, FLUORINATED; LIVER; MALE; MOLECULAR STRUCTURE; RATS; SEX CHARACTERISTICS;

RATTUS;

EID: 67349099866     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.03.015     Document Type: Article

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