Structural determinants of product specificity of sucrose isomerases

FEBS Letters

Volumn 583, Issue 12, 2009, Pages 1964-1968

  Ravaud, Stéphanie ^a   Robert, Xavier ^a   Watzlawick, Hildegard ^b   Haser, Richard ^a   Mattes, Ralf ^b   Aghajari, Nushin ^a  

^a INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

^b UNIVERSITY OF STUTTGART   (Germany)

Author keywords

Aromatic clamp; Crystal structure; Deoxynojirimycin; Glycoside hydrolase; Molecular modeling; Sucrose isomerase

Indexed keywords

ISOMERASE; PALATINOSE; SUCROSE ISOMERASE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; MOLECULAR MODEL; PRIORITY JOURNAL; SURFACE CHARGE;

1-DEOXYNOJIRIMYCIN; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ARGININE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; GAMMAPROTEOBACTERIA; GLUCOSAMINE; GLUCOSYLTRANSFERASES; INTRAMOLECULAR TRANSFERASES; ISOMALTOSE; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; PROTEIN CONFORMATION; STATIC ELECTRICITY; SUBSTRATE SPECIFICITY; SWEETENING AGENTS;

PROTAMINOBACTER RUBRUM;

EID: 67349097363     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.05.002     Document Type: Article

References (22)

1. Lina B.A., Jonker D., and Kozianowski G. Isomaltulose (palatinose): a review of biological and toxicological studies. Food. Chem. Toxicol. 40 (2002) 1375-1381
2. Cheetham P.S. The extraction and mechanism of a novel isomaltulose-synthesizing enzyme from Erwinia rhapontici. Biochem. J. 220 (1984) 213-220
3. Nagai Y., Sugitani T., and Tsuyuki K. Characterization of alpha-glucosyltransferase from Pseudomonas mesoacidophila MX-45. Biosci. Biotechnol. Biochem. 58 (1994) 1789-1793
4. Mattes, R., Klein, K., Schiweck, H., Kunz, M. and Munir, M. (1998) US Patent 5786140.
5. Veronese T., and Perlot P. Proposition for the biochemical mechanism occurring in the sucrose isomerase active site. FEBS Lett. 441 (1998) 348-352
6. Zhang D., Li N., Lok S.M., Zhang L.H., and Swaminathan K. Isomaltulose synthase (PalI) of Klebsiella sp. LX3. Crystal structure and implication of mechanism. J. Biol. Chem. 278 (2003) 35428-35434
7. Wu L., and Birch R.G. Characterization of the highly efficient sucrose isomerase from Pantoea dispersa UQ68J and cloning of the sucrose isomerase gene. Appl. Environ. Microbiol. 71 (2005) 1581-1590
8. Ravaud S., Watzlawick H., Mattes R., Haser R., and Aghajari N. Towards the three-dimensional structure of a sucrose isomerase from Pseudomonas mesoacidophila MX-45. Biologia Cell. Mol. Biol. Sec. 60 (2005) 99-105
9. Ravaud S., Robert X., Watzlawick H., Haser R., Mattes R., and Aghajari N. Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization. J. Biol. Chem. 282 (2007) 28126-28136
10. Ravaud S., Robert X., Watzlawick H., Laurent S., Haser R., Mattes R., and Aghajari N. Insights into sucrose isomerisation from crystal structures of the Pseudomonas mesoacidophila MX45 sucrose isomerase, MutB. Biocatal. Biotransfor. 26 (2008) 111-119
11. Zhang D., Li N., Swaminathan K., and Zhang L.H. A motif rich in charged residues determines product specificity in isomaltulose synthase. FEBS Lett. 534 (2003) 151-155
12. Ravaud S., Watzlawick H., Haser R., Mattes R., and Aghajari N. Overexpression, purification, crystallization and preliminary diffraction studies of the Protaminobacter rubrum sucrose isomerase SmuA. Acta Cryst. F62 (2006) 74-76
13. Kabsch W. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants. J. Appl. Cryst. 26 (1993) 795-800
14. Navaza J. Implementation of molecular replacement in AMoRe. Acta Cryst. D57 (2001) 1367-1372
15. Brünger A.T., et al. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Cryst. D54 (1998) 905-921
16. Roussel A., and Cambillau C. TURBO-FRODO (1992), Biographics AFMB, Marseille, France
17. Laskowski R.A., MacArthur M.W., Moss D.S., and Thornton J.M. PROCHECK: a program to check the stereochemical quality of protein structures. J. Appl. Crystallogr. 26 (1993) 283-291
18. Hooft R.W., Vriend G., Sander C., and Abola E.E. Errors in protein structures. Nature 381 (1996) 272
19. DeLano W.L. PyMOL (2002), DeLano Scientific, San Carlos, CA
20. Nicholls A., Sharp K.A., and Honig B. Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 11 (1991) 281-296
21. Yu J., Choi S.Y., Moon K.D., Chung H.H., Youn H.J., Jeong S., Park H., and Schultz P.G. A glycosidase antibody elicited against a chair-like transition state analog by in vitro immunization. Proc. Natl. Acad. Sci. USA 95 (1998) 2880-2884
22. Lee H.C., Kim J.H., Kim S.Y., and Lee J.K. Isomaltose production by modification of the fructose-binding site on the basis of the predicted structure of sucrose isomerase from Protaminobacter rubrum. Appl. Environ. Microbiol. 74 (2008) 5183-5194