Mechanics of carotid arteries in a mouse model of marfan syndrome

Annals of Biomedical Engineering

Volumn 37, Issue 6, 2009, Pages 1093-1104

  Eberth, J F ^a   Taucer, A I ^a   Wilson, E ^b   Humphrey, J D ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

Dissecting aneurysm; Fibrillin 1 (FBN1); MgR; Stress strain properties; Transgenic

Indexed keywords

DISSECTING ANEURYSM; FIBRILLIN-1 (FBN1); MGR; STRESS-STRAIN PROPERTIES; TRANSGENIC;

BIOMECHANICS; MECHANICAL PROPERTIES;

GLYCOPROTEINS;

ACTIN BINDING PROTEIN; FIBRILLIN;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; BIOMECHANICS; CAROTID ARTERY; DISEASE MODEL; ELASTICITY; FIBER; IN VITRO STUDY; MALE; MARFAN SYNDROME; MECHANICAL STRESS; METABOLISM; MOUSE; MUSCLE CONTRACTION; PATHOPHYSIOLOGY; PRESSURE; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

ANIMALS; BIOMECHANICS; CAROTID ARTERIES; DISEASE MODELS, ANIMAL; ELASTICITY; ENDOTHELIUM, VASCULAR; MALE; MARFAN SYNDROME; MICE; MICROFIBRILS; MICROFILAMENT PROTEINS; MODELS, CARDIOVASCULAR; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; PRESSURE; STRESS, MECHANICAL;

EID: 67349095579     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-009-9686-1     Document Type: Article

References (51)

1. E. Arteaga-Solis B. Gayraud F. Ramirez 2000 Elastic and collagenous networks in vascular diseases Cell Struct. Funct. 25 69 72 10.1247/csf.25.69
2. J. Atkinson 2008 Age-related medial elastocalcinosis in arteries: mechanisms, animal models, and physiological consequences J. Appl. Physiol. 105 1643 1651 10.1152/japplphysiol.90476.2008
3. S. Baek K. R. Rajagopal J. D. Humphrey 2006 A theoretical model of enlarging intracranial fusiform aneurysms J. Biomech. Eng. 128 142 149 10.1115/1.2132374
4. P. Boutouyrie C. Bussy P. Lacolley X. Girerd B. Laloux S. Laurent 1999 Association between local pulse pressure, mean blood pressure, and large-artery remodeling Circulation 100 1387 1393
5. L. J. Brossollet R. P. Vito 1995 An alternate formulation of blood vessel mechanics and the meaning of the in vivo property J. Biomech. 28 679 687 10.1016/0021-9290(94)00119-O
6. T. E. Bunton N. J. Biery L. Myers B. Gayraud F. Ramirez H. C. Dietz 2001 Phenotypic alteration of vascular smooth muscle cells precedes elastolysis in a mouse model of Marfan syndrome Circ. Res. 88 37 43
7. R. W. Carton J. Dainauskas J. W. Clark 1962 Elastic properties of single elastic fibers J. Appl. Physiol. 17 547 551
8. N. L. Charbonneau R. N. Ono G. M. Corson D. R. Keene L. Y. Sakai 2004 Fine tuning of growth factor signals depends on fibrillin microfibril networks Birth Defects Res. 72 37 50 10.1002/bdrc.20000
9. A. W. Chung K. Au Yeung G. G. Sandor D. P. Judge H. C. Dietz C. van Breemen 2007 Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome Circ. Res. 101 512 522 10.1161/CIRCRESAHA.107.157776
10. W. W. Dye R. L. Gleason E. Wilson J. D. Humphrey 2007 Altered biomechanical properties of carotid arteries in two mouse models of muscular dystrophy J. Appl. Physiol. 103 664 672 10.1152/japplphysiol.00118.2007
11. R. L. Gleason J. D. Humphrey 2005 Effects of a sustained extension on arterial growth and remodeling: a theoretical study J. Biomech. 38 1255 1261 10.1016/j.jbiomech.2004.06.017
12. R. L. Gleason J. D. Humphrey 2005 A 2D constrained mixture model for arterial adaptations to large changes in flow, pressure and axial stretch Math. Med. Biol. 22 347 369 10.1093/imammb/dqi014
13. R. L. Gleason W. W. Dye E. Wilson J. D. Humphrey 2008 Quantification of the mechanical behavior of carotid arteries from wild-type, dystrophin- deficient, and sarcoglycan-delta knockout mice J. Biomech. 41 3213 3218
14. R. L. Gleason S. P. Gray E. Wilson J. D. Humphrey 2004 A multiaxial computer-controlled organ culture and biomechanical device for mouse carotid arteries J. Biomech. Eng. 126 787 795 10.1115/1.1824130
15. R. L. Gleason L. A. Taber J. D. Humphrey 2004 A 2-D model of flow-induced alterations in the geometry, structure, and properties of carotid arteries J. Biomech. Eng. 126 371 381 10.1115/1.1762899
16. R. L. Gleason E. Wilson J. D. Humphrey 2007 Biaxial biomechanical adaptations of mouse carotid arteries cultured at altered axial extension J. Biomech. 40 766 776 10.1016/j.jbiomech.2006.03.018
17. S. E. Greenwald 2007 Ageing of the conduit arteries J. Pathol. 211 157 172 10.1002/path.2101
18. M. Groenink A. de Roos B. J. Mulder J. A. Spaan E. E. van der Wall 1998 Changes in aortic distensibility and pulse wave velocity assessed with magnetic resonance imaging following beta-blocker therapy in the Marfan syndrome Am. J. Cardiol. 82 203 208 10.1016/S0002-9149(98)00315-4
19. M. Groenink A. de Roos B. J. Mulder B. J. Verbeeten J. Timmermans A. H. Zwinderman J. A. Spaan E. E. van der Wall 2001 Biophysical properties of the normal-sized aorta in patients with Marfan syndrome: evaluation with MR flow mapping Radiology 219 535 540
20. J. P. Habashi D. P. Judge T. M. Holm R. D. Cohn B. L. Loeys T. K. Cooper L. Myers E. C. Klein G. Liu G. Liu C. Calvi M. Podowski E. R. Neptune D. Bedja K. Gabrielson D. B. Rifkin D. L. Huso H. C. Dietz 2006 Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome Science 312 117 121 10.1126/science.1124287
21. H. C. Han Y. C. Fung 1995 Longitudinal strain of canine and porcine aortas J. Biomech. 28 637 641 10.1016/0021-9290(94)00091-H
22. G. A. Holzapfel T. C. Gasser R. W. Ogden 2000 A new constitutive framework for arterial wall mechanics and a comparative study of material models J. Elasticity 61 1 48 10.1023/A:1010835316564
23. Hu, J. J., S. Baek, and J. D. Humphrey. Stress-strain behavior of the passive basilar artery in normotension and hypertension. J. Biomech. 40:2559-2563, 2007. doi: 10.1016/j.jbiomech.2006.11.007 ; Corrigendum J. Biomech. 41:239, 2008
24. Humphrey, J. D. Cardiovascular Solid Mechanics: Cells, Tissues, and Organs. New York; Springer, 2002.
25. J. D. Humphrey 2008 Vascular adaptation and mechanical homeostasis at tissue, cellular, and sub-cellular levels Cell Biochem. Biophys. 50 53 78 10.1007/s12013-007-9002-3
26. J. D. Humphrey J. F. Eberth W. W. Dye R. L. Gleason 2009 Fundamental role of axial stress in compensatory adaptations by arteries J. Biomech. 42 1 8 10.1016/j.jbiomech.2008.11.011
27. J. D. Humphrey K. R. Rajagopal 2003 A constrained mixture model for arterial adaptations to a sustained step change in blood flow Biomech. Model. Mechanobiol. 2 109 126 10.1007/s10237-003-0033-4
28. R. W. Jeremy H. Huang J. Hwa H. McCarron C. F. Hughes J. G. Richards 1994 Relation between age, arterial distensibility, and aortic dilatation in the Marfan syndrome Am. J. Cardiol. 74 369 373 10.1016/0002-9149(94)90405-7
29. G. Jondeau P. Boutouyrie P. Lacolley B. Laloux O. Dubourg J. P. Bourdarias S. Laurent 1999 Central pulse pressure is a major determinant of ascending aorta dilation in Marfan syndrome Circulation 99 2677 2681
30. J. A. Jones J. R. Barbour R. E. Stroud S. Bouges S. L. Stephens F. G. Spinale J. S. Ikonomidis 2008 Altered transforming growth factor-beta signaling in a murine model of thoracic aortic aneurysm J. Vasc. Res. 45 457 468 10.1159/000127437
31. P. Lacolley P. Challande S. Boumaza G. Cohuet S. Laurent P. Boutouyrie J. A. Grimaud D. Paulin J. M. Lamazière Z. Li 2001 Mechanical properties and structure of carotid arteries in mice lacking desmin Cardiovasc. Res. 51 178 187 10.1016/S0008-6363(01)00278-4
32. M. A. Lillie G. J. David J. M. Gosline 1998 Mechanical role of elastin-associated microfibrils in pig aortic elastic tissue Connect. Tissue Res. 37 121 141 10.3109/03008209809028905
33. L. Loufrani K. Matrougui D. Gorny M. Duriez I. Blanc B. I. Levy D. Henrion 2001 Flow (shear stress)-induced endothelium-dependent dilation is altered in mice lacking the gene encoding for dystrophin Circulation 103 864 870
34. V. Marque P. Kieffer B. Gayraud I. Lartaud-Idjouadiene F. Ramirez J. Atkinson 2001 Aortic wall mechanics and composition in a transgenic mouse model of Marfan syndrome Arterioscler. Thromb. Vasc. Biol. 21 1184 1189 10.1161/hq0701.092136
35. I. Masson P. Boutouyrie S. Laurent J. D. Humphrey M. Zidi 2008 Characterization of arterial wall mechanical behavior and stresses from human clinical data J. Biomech. 41 2618 2627 10.1016/j.jbiomech.2008.06.022
36. N. Mercier M. Osborne-Pellegrin K. El Hadri A. Kakou C. Labat L. Loufrani D. Henrion P. Challande S. Jalkanen B. Feve P. Lacolley 2006 Carotid arterial stiffness, elastic fibre network and vasoreactivity in semicarbazide-sensitive amine-oxidase null mouse Cardiovasc. Res. 72 349 357 10.1016/j.cardiores.2006. 08.008
37. D. M. Milewicz H. C. Dietz D. C. Miller 2005 Treatment of aortic disease in patients with Marfan syndrome Circulation 111 e150 e157 10.1161/01.CIR. 0000155243.70456.F4
38. E. R. Neptune P. A. Frischmeyer D. E. Arking L. Myers T. E. Bunton B. Gayraud F. Ramirez L. Y. Sakai H. C. Dietz 2003 Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome Nat. Genet. 33 407 411 10.1038/ng1116
39. M. F. O'Rourke J. Hashimoto 2007 Mechanical factors in arterial aging: a clinical perspective J. Am. Coll. Cardiol. 50 1 13 10.1016/j.jacc.2006.12.050
40. L. Pereira S. Y. Lee B. Gayraud K. Andrikopoulos S. D. Shapiro T. Bunton N. J. Biery H. C. Dietz L. Y. Sakai F. Ramirez 1999 Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1 Proc. Natl. Acad. Sci. USA 96 3819 3823 10.1073/pnas.96.7.3819
41. M. Pezet M. P. Jacob B. Escoubet D. Gheduzzi E. Tillet P. Perret P. Huber D. Quaglino R. Vranckx D. Y. Li B. Starcher W. A. Boyle R. P. Mecham G. Faury 2008 Elastin haploinsufficiency induces alternative aging processes in the aorta Rejuvenation Res. 11 97 112 10.1089/rej.2007.0587
42. R. Pyeritz 2000 The Marfan syndrome Annu. Rev. Med. 51 481 510 10.1146/annurev.med.51.1.481
43. F. Ramirez L. Pereira 1999 The fibrillins Int. J. Biochem. Cell Biol. 31 255 259 10.1016/S1357-2725(98)00109-5
44. M. E. Safar 2000 Pulse pressure, arterial stiffness, and cardiovascular risk Curr. Opin. Cardiol. 15 258 263 10.1097/00001573-200007000-00009
45. P. M. Schiffers D. Henrion C. M. Boulanger E. Colucci-Guyon F. Langa-Vuves H. van Essen G. E. Fazzi B. I. Levy J. G. De Mey 2000 Altered flow-induced arterial remodeling in vimentin-deficient mice Arterioscler. Thromb. Vasc. Biol. 20 611 616
46. M. J. Sherratt C. Baldock J. L. Haston D. F. Holmes C. J. Jones C. A. Shuttleworth T. J. Wess C. M. Kielty 2003 Fibrillin microfibrils are stiff reinforcing fibres in compliant tissues J. Mol. Biol. 332 183 193 10.1016/S0022-2836(03)00829-5
47. J. Stalhand A. Klarbring M. Karlsson 2004 Towards in vivo aorta material identification and stress estimation Biomech. Model. Mechanobiol. 2 169 186 10.1007/s10237-003-0038-z
48. P. Van Loon W. Klip E. L. Bradley 1977 Length-force and volume-pressure relationships of arteries Biorheology 14 181 201
49. J. E. Wagenseil N. L. Nerurkar R. H. Knutsen R. J. Okamoto D. Y. Li R. P. Mecham 2005 Effects of elastin haploinsufficiency on the mechanical behavior of mouse arteries Am. J. Physiol. Heart Circ. Physiol. 289 H1209 H1217 10.1152/ajpheart.00046.2005
50. H. Weizsacker H. Lambert K. Pascale 1983 Analysis of the passive mechanical properties of rat carotid arteries J. Biomech. 16 703 715 10.1016/0021-9290(83)90080-5
51. S. Zeinali-Davarani J. Choi S. Baek 2009 On parameter estimation for biaxial mechanical behavior of arteries J. Biomech. 42 524 530