Chemopreventive action of dexamethasone and α-tocopherol in oxidative stressed cells

Cancer Epidemiology

Volumn 32, Issue 5-6, 2009, Pages 452-457

  Baumeister, P ^a   Korn, G ^a   Berghaus, A ^a   Matthias, C ^b   Harreus U ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Tocopherol; Dexamethasone; Nasal cell cultures; Oxidative DNA damage

Indexed keywords

ALPHA TOCOPHEROL; DEXAMETHASONE; HYDROGEN PEROXIDE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CELL STRESS; CHEMOPROPHYLAXIS; COMET ASSAY; CONCENTRATION RESPONSE; DNA FRAGMENTATION; DOSE TIME EFFECT RELATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; MICROENVIRONMENT; NASAL BIOPSY; NOSE MUCOSA; ORGAN CULTURE; OXIDATIVE STRESS; PRIORITY JOURNAL; TREATMENT DURATION;

ALPHA-TOCOPHEROL; ANTI-INFLAMMATORY AGENTS; ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; COMET ASSAY; DEXAMETHASONE; DNA DAMAGE; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROGEN PEROXIDE; NASAL MUCOSA; ORGAN CULTURE TECHNIQUES; OXIDATION-REDUCTION; OXIDATIVE STRESS;

EID: 67349087920     PISSN: 18777821     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cdp.2008.10.002     Document Type: Article

References (42)

1. Dvorak H.F. Tumors: wound that do not heal. Similarities between tumor stroma generation and wound healing. N Eng J Med 315 (1986) 1650-1659
2. Dalgleish A.G., and O'Byrne K. Inflammation and cancer: the role of immune response and angiogenesis. Cancer Treat Res 130 (2006) 1-28
3. Schottenfield D., and Beebe-Dimmer J. Chronic inflammation: a common and important factor in the pathogenesis of neoplasia. CA Cancer J Clin 56 (2006) 69-83
4. Pelicano H., Carney D., and Huang P. ROS in cancer cells and therapeutic implications. Drug Resist Updat 7 (2004) 97-110
5. Manett L.J. Oxyradicals and DNA damage. Carcinogenesis 3 (2002) 361-370
6. Karihtala P., and Soini Y. Reactive oxygen species and antioxidant mechanisms in human tissue and their relation to malignanvcies. APMIS: acta pathologica, microbiologica, et immunologica Scandinavica 115 (2007) 81-103
7. Evans M.D., Dizdaroglu M., and Cooke M.S. Oxidative DNA damage and disease: induction, repair and significance. Mutat Res 567 (2004) 1-61
8. Le Page F., Guy A., Cadet J., Sarasin A., and Gentil A. Repair and mutagenic potency of 8-oxoG:A and 8-oxoG:C base pairs in mammalian cells. Nucl Acids Res 26 (1998) 1276-1281
9. Sen R., and Baltimore D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46 (1986) 705-716
10. Okamoto T., Sanda T., and Asamitsu K. NF-κB signaling and carcinogenesis. Curr Pharm Des 13 (2007) 447-462
11. Szlosarek P., Charles K.A., and Balkwill F.R. Tumour necrosis factor-α as a tumour promoter. Eur J Cancer 42 (2006) 745-750
12. Balkwill F., and Mantovani A. Inflammation and cancer: back to Virchow?. Lancet 357 (2001) 539-545
13. Coussens L.M., and Werb Z. Inflammation and cancer. Nature 420 (2002) 860-867
14. Kleinsasser N.H., Juchhoff J., Wallner B.C., Bergner A., Harréus U.A., Gamarra F., et al. The use of mini-organ cultures of human upper aerodigestive tract epithelia in ecogenotoxicology. Mutat Res 561 (2004) 63-73
15. Harréus U., Schmezer P., Kuchenmeister F., and Maier H. Genotoxic effect of human mucous membrane biopsies of the upper aerodigestive tract. Laryngorhinootologie 78 4 (1999) 176-181
16. Mygind N., and Andersson M. Topical clucocorticosteroids in rhinitis: clinical aspects. Acta Otolaryngol 126 10 (2006) 1022-1029
17. Barnes P.J. Corticosteroid effect on cell signalling. Eur Respir J 27 (2006) 413-426
18. Witkamp R., and Monshouwer M. Signal transduction in inflammatory processes, current and future therapeutic targets: a mini review. Vet Q 22 1 (2000) 11-16
19. Corda S., Laplace C., Vicaut E., and Duranteau J. Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factor-α I smediated by ceramide. Am J Respir Cell Mol Biol 24 (2001) 762-768
20. Ferro T.J., Hocking D.C., and Johnson A. Tumor necrosis factor-alpha alters pulmonary vasoreactivity via neutrophil-derived oxidants. Am J Physiol 265 (1993) 462-471
21. Hirst D.G., and Robson T. Nitrosative stress in cancer therapy. Front Biosci 12 (2007) 3406-3418
22. Reiter T.A. NO* chemistry: a diversity of targets in the cell. Redox Rep 11 (2006) 194-206
23. Halliwell B., and Whiteman M. Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?. Br J Pharmacol 142 (2004) 231-255
24. Iuchi T., Akaike M., Mitsui T., Ohshima Y., Shintani Y., Azuma H., et al. Glucocorticoid excess induces superoxide production in vascular endothelial cells and elicits vascular endothelial dysfunction. Circ Res 92 (2003) 81-87
25. Rahman I., Bel A., Mulier B., Donaldson K., and MacNee W. Differential regulation of glutathione by oxidants and dexamethasone in alveolar epithelial cells. Am J Physiol 275 (1998) L80-L86
26. Sadowska A.M., Klebe B., Germonpré P., and De Backer W.A. Glucocorticosteroids as antioxidants in treatment of asthma and COPD. New application for an old medication?. Steroids 72 (2007) 1-6
27. Block G., Patterson B., and Subar A. Fruit, vegetables and cancer prevention: a review of the epidemiologic evidence. Nutr Cancer 18 (1992) 1-29
28. Garewal H. Chemoprevention of oral cancer: beta-carotene and vitamin E in leukoplakia. Eur J Cancer Prev 3 (1994) 101-107
29. Albanes D., Heinonen O.P., Taylor P.R., Virtamo J., Edwards B.K., Rautalahti M., et al. Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance. J Natl Cancer Inst 88 (1996) 1560-1570
30. Wright M.E., Virtamo J., Hartman A.M., Pietinen P., Edwards B.K., Taylor P.R., et al. Effects of α-tocopherol and β-carotene supplementation on upper aerodigestive tract cancers in a large, randomized controlled trial. Cancer 109 (2007) 891-898
31. Bairati I., Meyer F., Jobin E., Gélinas M., Fortin A., Nabid A., et al. Antioxidant vitamins supplementation and mortality: a randomized trial in head and neck cancer patients. Int J Cancer 119 (2006) 2221-2224
32. Bairati I., Meyer F., Gélinas M., Fortin A., Nabid A., Brochet F., et al. A randomized trial of antioxidant vitamins to prevent second primary cancers in head and neck cancer patients. J Natl Cancer Inst 97 (2005) 481-488
33. Brigelius-Flohé R., Kelly F.J., Salonen J.T., Neuzil J., Zingg J.M., and Azzi A. The European perspective on vitamin E: current knowledge and future research. Am J Clin Nutr 76 (2002) 703-716
34. Cerecetto H., and Lopez G.V. Antioxidants derived from vitamin E: an overview. Mini Rev Med Chem 7 (2007) 315-338
35. Ekstrand-Hammarström B., Osterlund C., Lilliehöök B., Bucht A., and Vitamin. E down-modulates mitogen-activated protein kinases, nuclear factor- κB and inflammatory responses in lung epithelial cells. Clin Exp Immunol 147 (2007) 359-369
36. Betti M., Minelli A., Canonico B., Castaldo P., Magi S., Aisa M.C., et al. Antiproliferative effects of tocopherols (vitamin E) on murine glioma C6 cells: homologue-specific control of PKC/ERK and cyclin signaling. Free Radic Biol Med 41 (2006) 464-472
37. Azzi A., Ricciarelli R., and Zingg J.M. Non-antioxidant molecular functions of α-tocopherol (vitamin E). FEBS Lett 519 (2002) 8-10
38. 2. Free Radic Biol Med 34 (2003) 521-530
39. Choi J., Yoon S.H., Kim J.E., Rhee K.H., Youn H.S., and Chung M.H. Gene-specific oxidative DNA damage in helicobacter pylori-infected human gastric mucosa. Int J Cancer 99 (2002) 485-490
40. Devaraj S., and Jjalal I. Failure of vitamin E in clinical trials: is gamma-tocopherol the answer?. Nutr Rev 63 (2005) 290-293
41. Jiang Q., Christen S., Shigenaga M.K., and Ames B.N. Gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr 74 (2001) 714-722
42. Huand H.Y., and Appel L.J. Supplementation of diets with α-tocopherol reduces serum concentrations of γ- and δ-tocopherol in humans. J Nutr 133 (2003) 3137-3140