Determination hematotoxic and hepatotoxic effects of trichloroacetic acid at sublethal dosage in rats

Food and Chemical Toxicology

Volumn 47, Issue 6, 2009, Pages 1324-1326

  Celik, Ismail ^a   Temur, Atilla ^a  

^a YUZUNCU YIL UNIVERSITY   (Turkey)

Author keywords

Hematotoxic; Hepatotoxic; Rat; Trichloroacetic acid

Indexed keywords

BILIRUBIN; CHOLESTEROL; HEMOGLOBIN; PROTEIN; TRICHLOROACETIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILIRUBIN BLOOD LEVEL; BLOOD SAMPLING; BLOOD TOXICITY; CHOLESTEROL BLOOD LEVEL; ERYTHROCYTE; FEMALE; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; LETHAL DOSE; LEUKOCYTE; LIVER TOXICITY; MALE; MEAN CORPUSCULAR HEMOGLOBIN; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; THROMBOCYTE COUNT;

ANIMALS; BILIRUBIN; BLOOD CELL COUNT; BODY WEIGHT; CHOLESTEROL; FEMALE; HEMATOLOGIC DISEASES; HEPATITIS, TOXIC; MALE; RATS; RATS, SPRAGUE-DAWLEY; TRICHLOROACETIC ACID;

RATTUS;

EID: 67349086613     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.03.007     Document Type: Article

References (18)

1. Acharya S., Mehta K., Rodrigues S., et al. Administration of subtoxic doses of t-butyl alcohol and trichloroacetic acid to male Wistar rats to study the interactive toxicity. Toxicol. Lett. 80 (1995) 97-104
2. Arslan O., Sekeroǧlu M.R., Celik I., and Tarakci M. The inhibition effects of some pesticides on the activity of five serum enzymes in vitro. J. Environ. Sci. Health A 32 (1997) 361-365
3. Bryant B.J., Jokinen M.P., Eustis S.L., et al. Toxicity of monocholoroacetic acid administered by gavage to F344 rats and B6C3F1 mice for up to 13 weeks. Toxicology 72 (1992) 77-87
4. Celik I. Determination of toxicity of trichloroacetic acid in rats: 50 days drinking water study. Pestic. Biochem. Phys. 89 (2007) 39-45
5. Celik I., and Kara M. The effects of plant growth regulators on activity of eight serum enzymes in vitro. J. Environ. Sci. Health A 32 (1997) 1755-1961
6. Celik I., Camas H., Arslan O., Yegin E., and Kufrevioglu O.I. The effects of some pesticides on the activity of liver and erythrocyte enzymes in vitro. J. Environ. Sci. Health A 31 (1996) 1645-1649
7. Demir H., and Celik I. Acute effects of trichloroacetic acid on serum enzymes level and erythrocyte carbonic anhydrase activity of rats. Turk. J. Biol. 30 (2006) 121-125
8. Empster J.P. Effect of organochlorine insecticides on animal populations. In: Moriarty F. (Ed). Organo chlorine Insecticides; Persistent Organic Pollutants (1975), Academic Press, London 31
9. Mather G.G., Exon J.H., and Koller L.D. Subchronic 90 day toxicity of dichloroacetic and trichloroacetic acid in rats. Toxicology 64 (1990) 71-80
10. Poon R., Nadeau B., and Chu I. Biochemical effects of chloral hydrate on male rats following 7-day drinking water exposure. J. Appl. Toxicol. 20 (2000) 455-461
11. Poon R., Nakai J., Yagminas A., et al. Subchronic toxicity of chloral hydrate on rats: a drinking water study. J. Appl. Toxicol. 22 (2002) 227-236
12. Singh B., Saxena A.K., Chandan B.K., Anand K.K., Suri O.P., Suri K.A., and Satti N.K. Hepatoprotective activity of verbenalin on experimental liver damage in rodents. Fitoterapia 69 (1998) 134-140
13. Waliszevski S.M., Pardio Sedus V.T., and Waliszevski K.N. Detection of some organocholrine pesticides in cow's milk. Food Add. Contamin. 13 (1996) 231-235
14. nd WMA General Assembly, Edinburgh, Scotland. 2000.
15. Xing R., Liu S., Guo Z., Yu H., Wang P., Li C., Li Z., and Li P. Relevance of molecular weight of chitosan and its derivatives and their antioxidant activities in vitro. Bioorg. Med. Chem. 13 (2005) 1573-1577
16. Sirolli V., Ballone E., Garofalo D., Merciaro G., Settefrati N., Di Mascio R., Di Gregorio P., and Bonomini M. Platelet activation markers in patients with nephrotic syndrome. A comparative study of different platelet function tests. Nephron 91 (2002) 424-430
17. Tkaczyk M., and Baj Z. Surface markers of platelet function in idiopathic nephrotic syndrome in children. Pediatr. Nephrol. 17 (2002) 673-677
18. Kiliś-Pstrusińska K., Medyńska A., Wikiera-Magott I., and Zwolińska D. Levels of selected soluble adhesion molecules in blood serum of children with chronic glomerulonephritis. Pol. Merkuriusz Lek. 10 (2001) 247-249