Hydrophobic moiety of cationic lipids strongly modulates their transfection activity

Molecular Pharmaceutics

Volumn 6, Issue 3, 2009, Pages 951-958

  Koynova, Rumiana ^a,c   Tenchov, Boris ^a,b,c   Wang, Li ^a   MacDonald, Robert C ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b BULGARIAN ACADEMY OF SCIENCES   (Bulgaria)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

Cationic phospholipid; Cubic phase; Hexagonal phase; Hydrophobic chain; Lipoplex; Phosphatidylethanolamine; Transfection

Indexed keywords

LIPID; MEMBRANE LIPID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE;

ARTICLE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIPID TRANSPORT; LIPOPHILICITY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

CELL LINE; HUMANS; HYDROPHOBICITY; MOLECULAR STRUCTURE; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; X-RAY DIFFRACTION;

EID: 67249113972     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp8002573     Document Type: Article

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