Single subcutaneous administration of RGDK-lipopeptide:rhPDGF-B gene complex heals wounds in streptozotocin-induced diabetic rats

Molecular Pharmaceutics

Volumn 6, Issue 3, 2009, Pages 918-927

  Bhattacharyya, Jayanta ^a   Mondal, Goutam ^a   Madhusudana, Kuncha ^a   Agawane, Sachin B ^a   Ramakrishna, Sistla ^a   Gangireddy, Srinivasa R ^b   Madhavi, Radha D ^b   Reddy, Praveen K ^b   Konda, Venkat R ^b   Rao, Siripuramparthasaradi Ramakrishna ^b   Udaykumar, Putchaa ^c   Chaudhuri, Arabinda ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b Virchow Research Foundation   (India)

^c NATIONAL INSTITUTE OF NUTRITION   (India)

Author keywords

Chronic wounds; Liposomal gene delivery; PDGF B growth factor; RGDK lipopeptide

Indexed keywords

ARGINYLGLYCYLASPARTYLLYSINE LIPOPEPTIDE 1; CHOLESTEROL; DNA; EOSIN; HEMATOXYLIN; LIPOPEPTIDE; MONOCLONAL ANTIBODY; PLASMID DNA; PLATELET DERIVED GROWTH FACTOR B; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC WOUND; CONTROLLED STUDY; DRUG UPTAKE; EPITHELIZATION; FIBROBLAST; FIBROCOLLAGENATION; GENE EXPRESSION; GENETIC TRANSFECTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; KERATINIZATION; LIPOSOMAL GENE DELIVERY SYSTEM; MALE; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; RAT; REGENERATION; STREPTOZOCIN DIABETES; WESTERN BLOTTING; WOUND HEALING;

3T3 CELLS; ANIMALS; BLOTTING, WESTERN; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; FIBROBLASTS; GENE THERAPY; HUMANS; LIPOPEPTIDES; LIPOSOMES; MALE; MICE; MODELS, GENETIC; MOLECULAR STRUCTURE; PROTO-ONCOGENE PROTEINS C-SIS; RATS; RATS, SPRAGUE-DAWLEY; TRANSFECTION; WOUND HEALING;

EID: 67249113105     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp800231z     Document Type: Article

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