MRI observation of apoptotic cells using superparamagnetic iron oxide nanoparticles labeled Annexin V in vitro

Chinese Journal of Medical Imaging Technology

Volumn 25, Issue 5, 2009, Pages 734-737

  Li, Zong Fang ^a   Liu, Liu ^a   Tian, Wei ^a   Teng, Gao Jun ^b   Zhang, Yu ^b   Ge, Yu Qing ^b   Wang, Fu Ke ^a  

^a KUNMING MEDICAL UNIVERSITY   (China)

^b SOUTHEAST UNIVERSITY   (China)

Author keywords

Annexin V; Apoptosis; Magnetic resonance imaging

Indexed keywords

FERRIC FERROCYANIDE; HYDROGEN PEROXIDE; LIPOCORTIN 5; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; FEASIBILITY STUDY; IN VITRO STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RAT;

EID: 67249103808     PISSN: 10033289     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Luo QY, Zhu RS. Imaging modalities for in vivo detection of apoptosis. Chin J Med Imaging Technol,2004,20(10):1620-1623.
2. 99mTc-Annexin B1 as a novel radiotracer for apoptosis imaging. Chin J Med Imaging Technol,2008,24(8):1177-1181.
3. Mattson MP, Culmsee C, Yu ZF, et al. Apoptotic and antiapoptotic mechanisms in stroke. Cell Tissue Res,2000,301(1):163-171. (Pubitemid 30459864)
4. Mattsson P, Delfani K, Janson AM, et al. Motor neuronal and glial apoptosis in the adult facial nucleus after intracranial nerve transection. J Neurosurg,2006,104(3):457-460. (Pubitemid 43326848)
5. Zhao M, Beauregard DA, Loizou L, et al. Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent. Nat Med,2001,7(11):1241-1244. (Pubitemid 33063780)
6. Schellenberger EA, Bogdanov A Jr, Högemann D, et al. Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI. Mol Imaging,2002,1(2):102-107.
7. Schellenberger EA, Sosnovik D, Weissleder R, et al. Magneto/optical annexin V, a multimodal protein. Bioconjug Chem,2004,15(5):1062-1067.
8. Sosnovik DE, Schellenberger EA, Nahrendorf M, et al. Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle. Magn Reson Med,2005,54(3):718-724. (Pubitemid 41233769)
9. van Tilborg GA, Mulder WJ, Deckers N, et al. Annexin A5-functionalized bimodal lipid-based contrast agents for the detection of apoptosis. Bioconjug Chem,2006,17(3):741-749. (Pubitemid 43794385)