Both systemic and local application of Granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy

BMC Neuroscience

Volumn 10, Issue , 2009, Pages

  Frank, Tobias ^a   Schlachetzki, Johannes C M ^a   Göricke, Bettina ^a,b   Meuer, Katrin ^a   Rohde, Gundula ^a,b   Dietz, Gunnar P H ^a,b,c   Bähr, Mathias ^a,b   Schneider, Armin ^d   Weishaupt, Jochen H ^a,b  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b Deutsche Forschungsgemeinschaft   (Germany)

^c H LUNDBECK A S   (Denmark)

^d SYGNIS Bioscience   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; NEUROTROPHIC FACTOR; NEUROTROPHIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG MECHANISM; DRUG SAFETY; FEMALE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; LEUKOCYTE COUNT; LEUKOCYTOSIS; LOCAL THERAPY; NERVE CELL CULTURE; NERVE CELL NECROSIS; NERVE FIBER TRANSECTION; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; RAT; RETINA DEGENERATION; RETINA GANGLION CELL; STEM CELL MOBILIZATION; SYSTEMIC THERAPY; ANALYSIS OF VARIANCE; ANIMAL; COMPARATIVE STUDY; DRUG EFFECT; METABOLISM; NERVE DEGENERATION; NONPARAMETRIC TEST; OPTIC NERVE INJURY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; SUBCUTANEOUS DRUG ADMINISTRATION; VITREOUS BODY;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; AXOTOMY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; INJECTIONS, SUBCUTANEOUS; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; OPTIC NERVE INJURIES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GRANULOCYTE COLONY-STIMULATING FACTOR; RETINAL GANGLION CELLS; STATISTICS, NONPARAMETRIC; VITREOUS BODY;

EID: 67249092962     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-10-49     Document Type: Article

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