Rheumatic manifestations associated with HIV in the highly active antiretroviral therapy era

Current Opinion in Rheumatology

Volumn 21, Issue 4, 2009, Pages 404-410

  Nguyen, Binh Y ^a   Reveille, John D ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Antitumor necrosis factor; Arthritis; Highly active antiretroviral therapy (HAART); HIV; Myositis

Indexed keywords

ANTIRETROVIRUS AGENT; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DIDANOSINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN; INDINAVIR; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PROTEINASE INHIBITOR; RALTEGRAVIR; TUMOR NECROSIS FACTOR INHIBITOR; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ALLERGIC VASCULITIS; ANAPHYLACTOID PURPURA; ANKYLOSING SPONDYLITIS; ARTHRALGIA; ARTHRITIS; AUTOIMMUNE DISEASE; AVASCULAR NECROSIS; BACTERIAL ARTHRITIS; BEHCET DISEASE; BONE NECROSIS; CD4 LYMPHOCYTE COUNT; CHURG STRAUSS SYNDROME; CLINICAL FEATURE; CONNECTIVE TISSUE DISEASE; CRYPTOCOCCOSIS; CUTANEOUS VASCULITIS; DERMATOMYOSITIS; DIFFUSE INFILTRATIVE LYMPHOCYTOSIS SYNDROME; DISEASE EXACERBATION; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; DRUG WITHDRAWAL; DUPUYTREN CONTRACTURE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMEROSCAPULAR PERIARTHRITIS; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; IMMUNITY; INFECTION; INFLAMMATORY DISEASE; KAPOSI SARCOMA; LEPROSY; LIPOMATOSIS; LOW DRUG DOSE; LYMPHOCYTOSIS; MITOCHONDRIAL MYOPATHY; MUCOCUTANEOUS LYMPH NODE SYNDROME; MUSCULOSKELETAL DISEASE; MYCOBACTERIUM INTRACELLULARE AVIUM; MYOPATHY; NEMALINE MYOPATHY; OSTEOMYELITIS; OSTEOPENIA; OSTEOPOROSIS; POLYARTERITIS NODOSA; POLYMYOSITIS; PREVALENCE; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; PSORIASIS; PSORIATIC ARTHRITIS; REACTIVE ARTHRITIS; REVIEW; RHABDOMYOLYSIS; RHEUMATIC DISEASE; RHEUMATOID ARTHRITIS; SARCOIDOSIS; SYSTEMIC LUPUS ERYTHEMATOSUS; TEMPOROMANDIBULAR JOINT DISORDER; TENOSYNOVITIS; TUBERCULOSIS; VASCULITIS; VIRUS LOAD; WASTING SYNDROME; WEGENER GRANULOMATOSIS;

ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; ANTIRHEUMATIC AGENTS; AUTOIMMUNE DISEASES; HIV INFECTIONS; HUMANS; IATROGENIC DISEASE; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; IMMUNE SYSTEM; MUSCULOSKELETAL DISEASES; RHEUMATIC DISEASES;

EID: 67149138180     PISSN: 10408711     EISSN: None     Source Type: Journal    
DOI: 10.1097/BOR.0b013e32832c9d04     Document Type: Review

References (69)

1. Yao Q, Frank M, Glynn M, Altman RD. Rheumatic manifestations in HIV-1 infected in-patients and literature review. Clin Exp Rheumatol 2008; 26:799-806. This retrospective study reported a prevalence of 5.5% of arthralgia/arthritis in individuals with HIV infection and an overall prevalence of 9% of rheumatic manifestations.
2. Mody GM, Parke FA, Reveille JD. Articular manifestations of human immunodeficiency virus infection. Best Pract Res Clin Rheumatol 2003; 17:265-287. (Pubitemid 36722159)
3. Njobvu P, McGiII P, Kerr H, et al. Spondyloarthropathy and human immunodeficiency virus infection in Zambia. J Rheumatol 1998; 25:1553-1559. (Pubitemid 28364762)
4. Berman A, Espinoza LR, Diaz JD, et al. Rheumatic manifestations of human immunodeficiency virus infection. Am J Med 1988; 85:59-64. (Pubitemid 18172186)
5. Forman SB, Higginson R, Garrett AB. Psoriasis and psoriatic arthritis in a patient with HIV: response to mycophenolate mofetil treatment. J Drugs Dermatol 2008; 7:972-973.
6. Mikhail M, Weinberg JM, Smith BL. Successful treatment with etanercept of von Zumbusch pustular psoriasis in a patient with human immunodeficiency virus. Arch Dermatol 2008; 144:453-456. (Pubitemid 351581101)
7. Williams FM, Cohen PR, Jumshyd J, Reveille JD. Prevalence of the diffuse infiltrative lymphocytosis syndrome among human immunodeficiency virus type 1-positive outpatients. Arthritis Rheum 1998; 41:863-868. (Pubitemid 28225787)
8. Itescu S, Brancato U, Buxbaum J, et al. A diffuse infiltrative CD8 lymphocytosis syndrome in human immunodeficiency virus (HIV) infection: A host immune response associated with HLA-DR5. Ann Intern Med 1990; 112:3-10. (Pubitemid 20026362)
9. Kazi S, Cohen PR, Williams F, et al. The diffuse infiltrative lymphocytosis syndrome: Clinical and immunogenetic features in 35 patients. AIDS 1996; 10:385-391.
10. Itescu S, Winchester R. Diffuse infiltrative lymphocytosis syndrome: A disorder occurring in human immunodeficiency virus-1 infection that may present as a sicca syndrome. Rheumatic Dis Clin North Am 1992; 18:683-697.
11. Itescu S, Dalton J, Zhang HZ, Winchester R. Tissue infiltration in a CD8 lymphocytosis syndrome associated with human immunodeficiency virus-1 infection has the phenotypic appearance of an antigenically driven response. J Clin Investig 1993; 91:2216. (Pubitemid 23141498)
12. Itescu S. Diffuse infiltrative lymphocytosis syndrome in human immunodeficiency virus infection: a Sjögren's-like disease. Rheum Dis Clin North Am 1991; 17:99-115.
13. Basu D, Williams FM, Ahn CW, Reveille JD. Changing spectrum of the diffuse infiltrative lymphocytosis syndrome. Arthritis Rheum 2006; 55:466-472. (Pubitemid 43887033)
14. Chetty R, Batitang S, Nair R. Large artery vasculopathy in HIV-positive patients: another vasculitic enigma. Human Pathol 2000; 31:374-379. (Pubitemid 30161358)
15. Velez AP, Menezes L, Crespo A. Kawasaki-like syndrome possibly associated with immune reconstitution inflammatory syndrome in an HIV-positive patient. AIDS Read 2006; 16:464-466. (Pubitemid 44744564)
16. Nguyen H, Ferentz K, Patel A, Le C. Churg-Strauss syndrome associated with HIV infection. J Am Board Fam Pract 2005; 18:140-142. (Pubitemid 41664018)
17. Sugimoto T, Tsuda A, Kito K, et al. Henoch-Schönlein purpura in a patient with human immunodeficiency virus infection. Rheumatol Int 2008; 28:615-616.
18. Cicalini S, Gigli B, Palmieri F, et al. Remission of Behçet's disease and keratoconjunctivitis sicca in an HIV-infected patient treated with HAART. Int J STD AIDS 2004; 15:139-140.
19. Herranz P, Fernández-Díaz ML, de Lucas R, et al. Cutaneous vasculitis associated with didanosine. Lancet 1994; 344:680. (Pubitemid 24274319)
20. Torres RA, Lin RY, Lee M, Barr MR. Zidovudine-induced leukocytoclastic vasculitis. Arch Intern Med 1992; 152:850-851.
21. Kaye BR. Rheumatologic manifestations of infection with human immunodeficiency virus (HIV). Ann Intern Med 1989; 111:158-167. (Pubitemid 19180327)
22. Fabris P, Tositti G, Giordani MT, et al. Prevalence and clinical significance of circulating cryoglobulins in HIV-positive patients with and without co-infection with hepatitis C virus. J Med Virol 2003; 69:339-343. (Pubitemid 36158313)
23. Klaassen RJ, Goldschmeding R, Dolman KM, et al. Antineutrophil cytoplasmic autoantibodies in patients with symptomatic HIV infection. Clin Exp Immunol 1992; 87:24-30.
24. Canoso RT, Zon LI, Groopman JE. Anticardiolipin antibodies associated with HTLV-III infection. Br J Haematol 1987; 65:495-498. (Pubitemid 17073771)
25. Hazarika I, Chakravarty BP, Dutta S, Mahanta N. Emergence of manifestations of HIV infection in a case of systemic lupus erythematosus following treatment with IV cyclophosphamide. Clin Rheumatol 2006; 25:98-100.
26. Wegrzyn J, Livrozet JM, Touraine JL, Miossec P. Rheumatoid arthritis after 9 years of humain immunodeficiency virus infection. Possible contribution of tritherapy. J Rheumatol 2002; 29:2232-2234.
27. Muller-Ladner U, Kriegsmann J, Gay RE, et al. Progressive joint destruction in a human immunodeficiency virus-infected patient with rheumatoid arthritis. Arthritis Rheum 1995; 38:1328-1332.
28. Azeroual A, Harmouche H, Benjilali L, et al. Rheumatoid arthritis associated to HIV infection. Eur J Intern Med 2008; 19:e34-e35.
29. Johnson RW, Williams FM, Kazi S, et al. Human immunodeficiency virus-associated polymyositis: a longitudinal study of outcome. Arthritis Rheum 2003; 49:172-178. (Pubitemid 36418274)
30. Masanés F, Pedrol E, Grau JM, et al. Symptomatic myopathies in HIV-1 infected patients untreated with antiretroviral agents - a clinico-pathological study of 30 consecutive patients. Clin Neuropathol 1996; 15:221-225. (Pubitemid 26232621)
31. Illa I, Nath A, Dalakas M. Immunocytochemical and virological characteristics of HIV-associated inflammatory myopathies: similarities with seronegative polymyositis. Ann Neurol 1991; 29:474-481.
32. Marfatia YS, Ghiya RA, Chaudhary D. Dermatomyositis in a human immunodeficiency virus infected person. Indian J Dermatol Venereol Leprol 2008; 74:241-243. (Pubitemid 351918879)
33. de Sanctis JT, Cumbo-Nacheli G, Dobbie D, Baumgartner D. HIV-associated nemaline rod myopathy: role of intravenous immunoglobulin therapy in two persons with HIV/AIDS. AIDS Read 2008; 18:90-94. This is a case report of successful treatment of nemaline rod myopathy with intravenous immunoglobulin therapy. (Pubitemid 351238531)
34. Prabahar MR, Jain M, Chandrasekaran V, et al. Primary HIV infection presenting as nontraumatic rhabdomyolysis with acute renal failure. Saudi J Kidney Dis Transpl 2008; 19:636-642.
35. Lebrecht D, Deveaud C, Beauvoit B, et al. Uridine supplementation antagonizes zidovudine-induced mitochondrial myopathy and hyperlactatemia in mice. Arthritis Rheum 2008; 58:318-326.
36. Masanes F, Barrientos A, Cebrian M, et al. Clinical, histological and molecular reversibility of zidovudine myopathy. J Neurol Sci 1998; 159:226-228.
37. Zembower TR, Gerzenshtein L, Coleman K, Palella FJ Jr. Severe rhabdomyolysis associated with raltegravir use. AIDS 2008; 22:1382-1384. This is a case report associating newly approved integrease inhibitor with rhabdomyolysis.
38. Mah Ming JB, Gill MJ. Drug-induced rhabdomyolysis after concomitant use of clarithromycin, atorvastatin, and lopinavir/ritonavir in a patient with HIV. AIDS Patient Care STDS 2003; 17:207-210. (Pubitemid 36583344)
39. Florence E, Schrooten W, Verdonck K, et al. Rheumatological complications associated with the use of indinavir and other protease inhibitors. Ann Rheum Dis 2002; 61:82-84. (Pubitemid 34074849)
40. Vassilopoulos D, Chalasani P, Jurado RL, et al. Musculoskeletal infections in patients with human immunodeficiency virus infection. Medicine (Baltimore) 1997; 76:284-294. (Pubitemid 27357868)
41. Hirsch R, Miller SM, Kazi S, et al. Human immunodeficiency virus associated with atypical mycobacterial skeletal infarctions. Semin Arthritis Rheum 1996; 25:347-356.
42. Kahlon SS, East JW, Sarria JC. Mycobacterium-avium-intracellulare complex immune reconstitution inflammatory syndrome in HIV/AIDS presenting as osteomyelitis. AIDS Read 2008; 18:515-518. This is a report of MAC osteomyelitis associated with IRIS.
43. Mary-Krause M, Billaud E, Poizot-Martin I, et al., Clinical Epidemiology Group of the French Hospital Database. Risk factors for osteonecrosis in HIV-infected patients: impact of treatment with combination antiretroviral therapy. AIDS 2006; 20:1627-1635.
44. Glesby MJ, Hoover DR, Vaamonde CM. Osteonecrosis in patients infected with human immunodeficiency virus: a case-control study. J Infect Dis 2001; 184:519-523. (Pubitemid 32718519)
45. Sighinolfi L, Carradori S, Ghinelli F. Avascular necrosis of the femoral head: a side effect of highly active antiretroviral therapy (HAART) in HIV patients? Infection 2000; 28:254-255. (Pubitemid 30601429)
46. Miller KD, Masur H, Jones EC, et al. High prevalence of osteonecrosis of the femoral head in HIV-infected adults. Ann Intern Med 2002; 137:17-25. (Pubitemid 34705372)
47. Harzy T, Berrady R, Tizniti S, Bono W. Osteonecrosis of the femoral heads and human immunodeficiency virus. J Clin Rheumatol 2008; 14:190.
48. Johnson MD, Decker CF. Osteonecrosis in HIV-infected persons: radiographic findings delay clinical diagnosis. AIDS Read 2008; 18:124-126; 132-133
49. Larrafiaga GD, Bottaro E, Martinuzzo M, et al. Thrombophilia in human immunodeficiency virus infected patients with osteonecrosis: is there a real connection? The first case-control study. Clin Appl Thromb Hemost 2007. doi: 1076029607310217v1. [Epub ahead of print]
50. Glesby MJ. Bone disorders in human immunodeficiency virus infection. Clin InfectDis 2003; 37 (Suppl 2):S91-S95. (Pubitemid 37102730)
51. Pouchot J, Simonpoli AM, Bortolotti V, et al. Painful articular sydrome and human immunodeficiency virus infection. Arch Intern Med 1992; 152:646-649.
52. Calabrese LH, Kirchner E, Shrestha R. Rheumatic complications of human immunodeficiency virus infection in the era of highly active antiretroviral therapy: emergence of a new syndrome of immune reconstitution and changing patterns of disease. Semin Arthritis Rheum 2005; 35:166-174. (Pubitemid 41713956)
53. Wegrzyn J, Livrozet JM, Touraine JL, Miossec P. Rheumatoid arthritis after 9 years of human immunodeficiency virus infection: possible contribution of tritherapy. J Rheumatol 2002; 29:2232-2234.
54. Diri E, Lipsky PE, Berggren RE. Emergence of systemic lupus erythematosus after initiation of highly active antiretroviral therapy for human immunodeficiency virus infection. J Rheumatol 2000; 27:2711-2714. (Pubitemid 30847953)
55. Calza L, Manfredi R, Colangeli V, et al. Polymyositis associated with HIV infection during immune restoration induced by highly active antiretroviral therapy. Clin Exp Rheumatol 2004; 22:651-652. (Pubitemid 39302948)
56. DelVecchio S, Skidmore P. Adult-onset Still's disease presenting as fever of unknown origin in a patient with HIV infection. Clin Infect Dis 2008; 46:e41-e43. This is a case study reporting HIV-associated AOSD. (Pubitemid 351263517)
57. French MA, Lewin SR, Dykstra C, Krueger R, Price P, Leedman PJ. Graves' disease during immune reconstitution after highly active antiretroviral therapy for HIV infection: evidence of thymic dysfunction. AIDS Res Hum Retroviruses 2004; 20:157-162. (Pubitemid 38280926)
58. Foulon G, Wislez M, Naccache JM, et al. Sarcoidosis in HIV-infected patients in the era of highly active antiretroviral therapy. Clin Infect Dis 2004; 38:418-425. (Pubitemid 38200122)
59. French MA, Price P. Immune restoration disease in HIV-infected patients after antiretroviral therapy. Clin Infect Dis 2001; 32:325-326. (Pubitemid 32524815)
60. Shelburne SA 3rd, Hamill RJ, Rodriguez-Barradas MC, et al. Immune reconstitution inflammatory syndrome: emergence of a unique syndrome during highly active antiretroviral therapy. Medicine (Baltimore) 2002; 81:213-227.
61. French MA, Lenzo N, John M, et al. Immune restoration disease after the treatment of immunodeficient HIV-infected patients with highly active antiretroviral therapy. HIV Med 2000; 1:107-115.
62. Srikantiah P, Walusimbi MN, Kayanja HK, et al. Early virological response of lidovudine/lamivudine/abacavir for patients co-infected with HIV and tuberculosis in Uganda. AIDS 2007; 21:1972-1974. (Pubitemid 47329776)
63. Burman W, Weis S, Vernon A, et al. Frequency, severity and duration of immune reconstitution events in HIV-related tuberculosis. Int J Tuberc Lung Dis 2007; 11:1282-1289.
64. Shelburne SA 3rd, Darcourt J, White AC Jr, et al. The Role of Immune Reconstitution Inflammatory Syndrome in AIDS-related Cryptococcus neoformans disease in the era of highly active antiretroviral therapy. Clin Inf Dis 2005; 40:1049-1053.
65. Bourinbaiar AS, Lee-Huang S. The nonsteroidal anti-inflammatory drug, indomethacin, as an inhibitor of HIV replication. FEBS Lett 1995; 360:85-88.
66. Chiang G, Sassaroli M, Louie M, et al. Inhibition of HIV-1 replication by hydroxychloroquine: mechanism of action and comparison with zidovudine. Clin Ther 1996; 18:1080-1092. (Pubitemid 27077112)
67. Disla E, Rhim HR, Reddy A, Taranta A. Improvement in CD4 lymphocyte count in HIV-Reiter's syndrome after treatment with sulfasalazine. J Rheumatol 1994; 21:662-664. (Pubitemid 24126761)
68. Cepeda EJ, Williams FM, Ishimori ML, et al. The use of antitumour necrosis factor therapy in HIV-positive individuals with rheumatic disease. Ann Rheum Dis 2008; 67:710-712. This is prospective study showed that anti-TNF agents did not adversely affect the viral load or CD4 counts. (Pubitemid 351571938)
69. Gill H, Majithia V. Successful use of infliximab in the treatment of Reiter's syndrome: a case report and discussion. Clin Rheumatol 2008; 27:121-123. (Pubitemid 350182690)