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Volumn 11, Issue 12, 2009, Pages 2531-2534

Total synthesis of brevenal

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DERIVATIVE; ETHER DERIVATIVE; THIOBUTABARBITAL; THIOPENTAL;

EID: 67149128372     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol900769d     Document Type: Article
Times cited : (59)

References (32)
  • 3
    • 27744466223 scopus 로고    scopus 로고
    • The antagonistic effect of brevenal on brevetoxin-induced DNA damage is reported, see
    • The antagonistic effect of brevenal on brevetoxin-induced DNA damage is reported, see: Sayer, A.; Hu, Q.; Bourdelais, A. J.; Baden, D. G.; Gibson, J. E. Arch. Toxicol. 2005, 79, 683-688.
    • (2005) Arch. Toxicol , vol.79 , pp. 683-688
    • Sayer, A.1    Hu, Q.2    Bourdelais, A.J.3    Baden, D.G.4    Gibson, J.E.5
  • 14
    • 67149104383 scopus 로고    scopus 로고
    • Sasaki and co-workers have reported the same C-C bond formation with this alkyl borate: see ref 4
    • Sasaki and co-workers have reported the same C-C bond formation with this alkyl borate: see ref 4.
  • 20
    • 0001268766 scopus 로고    scopus 로고
    • For the original conditions, see: a
    • For the original conditions, see: (a) Dahanukar, V. H.; Rychnovsky, S. D. J. Org. Chem. 1996, 61, 8317-8320
    • (1996) J. Org. Chem , vol.61 , pp. 8317-8320
    • Dahanukar, V.H.1    Rychnovsky, S.D.2
  • 23
    • 67149147478 scopus 로고    scopus 로고
    • None of the other stereoisomers were detected. Although the reaction conditions were optimized, partial decompsition of the substrate 2 was observed in this reaction.
    • None of the other stereoisomers were detected. Although the reaction conditions were optimized, partial decompsition of the substrate 2 was observed in this reaction.
  • 26
    • 67149108771 scopus 로고    scopus 로고
    • The reaction of 25 required 3 equiv of 26 for the completion, and the formation of unidentified by-products was observed.
    • The reaction of 25 required 3 equiv of 26 for the completion, and the formation of unidentified by-products was observed.
  • 27
    • 67149106210 scopus 로고    scopus 로고
    • For successful examples of the deprotection of TCBn group in similar cases, see ref 12
    • For successful examples of the deprotection of TCBn group in similar cases, see ref 12.
  • 29
    • 67149125997 scopus 로고    scopus 로고
    • 13C NMR spectra of 28 were identical with those reported previously.
    • 13C NMR spectra of 28 were identical with those reported previously.
  • 32
    • 67149115567 scopus 로고    scopus 로고
    • For the preparation of the phosphonate 33, see Supporting Information.
    • For the preparation of the phosphonate 33, see Supporting Information.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.