메뉴 건너뛰기




Volumn 5, Issue , 2009, Pages

Understanding the regulation of aspartate metabolism using a model based on measured kinetic parameters

Author keywords

Allosteric regulation; Arabidopsis; Aspartate metabolism; Mathematical model; Simulation

Indexed keywords

ASPARTIC ACID; ISOENZYME; THREONINE; AMINO ACID; RECOMBINANT PROTEIN;

EID: 67149116887     PISSN: 17444292     EISSN: 17444292     Source Type: Journal    
DOI: 10.1038/msb.2009.29     Document Type: Article
Times cited : (105)

References (63)
  • 2
    • 33645237056 scopus 로고    scopus 로고
    • The aspartic acid metabolic pathway, an exciting and essential pathway in plants
    • Azevedo RA, Lancien M, Lea PJ (2006) The aspartic acid metabolic pathway, an exciting and essential pathway in plants. Amino Acids 30:143-162
    • (2006) Amino Acids , vol.30 , pp. 143-162
    • Azevedo, R.A.1    Lancien, M.2    Lea, P.J.3
  • 4
    • 0037311116 scopus 로고    scopus 로고
    • Variation of glucosinolate accumulation among different organs and developmental stages of Arabidopsis thaliana
    • Brown PD, Tokuhisa JG, Reichelt M, Gershenzon J (2003) Variation of glucosinolate accumulation among different organs and developmental stages of Arabidopsis thaliana. Phytochemistry 62: 471-481
    • (2003) Phytochemistry , vol.62 , pp. 471-481
    • Brown, P.D.1    Tokuhisa, J.G.2    Reichelt, M.3    Gershenzon, J.4
  • 5
    • 0035365847 scopus 로고    scopus 로고
    • An integrated study of threonine-pathway enzyme kinetics in Escherichia coli
    • Chassagnole C, Rais B, Quentin E, Fell DA, Mazat JP (2001) An integrated study of threonine-pathway enzyme kinetics in Escherichia coli. Biochem J 356: 415-423
    • (2001) Biochem J , vol.356 , pp. 415-423
    • Chassagnole, C.1    Rais, B.2    Quentin, E.3    Fell, D.A.4    Mazat, J.P.5
  • 6
    • 0035667360 scopus 로고    scopus 로고
    • Information transfer in metabolic pathways. Effects of irreversible steps in computer models
    • Cornish-Bowden A, Cárdenas ML (2001) Information transfer in metabolic pathways. Effects of irreversible steps in computer models. Eur J Biochem 268: 6616-6624
    • (2001) Eur J Biochem , vol.268 , pp. 6616-6624
    • Cornish-Bowden, A.1    Cárdenas, M.L.2
  • 8
    • 0029585284 scopus 로고
    • Strategies for manipulating metabolic fluxes in biotechnology
    • Cornish-Bowden A, Hofmeyr JHS, Cárdenas ML (1995) Strategies for manipulating metabolic fluxes in biotechnology. Bioorg Chem 23: 439-449
    • (1995) Bioorg Chem , vol.23 , pp. 439-449
    • Cornish-Bowden, A.1    Hofmeyr, J.H.S.2    Cárdenas, M.L.3
  • 9
    • 0034731360 scopus 로고    scopus 로고
    • Arabidopsis loss-of-function mutant in the lysine pathway points out complex regulation mechanisms
    • Craciun A, Jacobs M, Vauterin M (2000) Arabidopsis loss-of-function mutant in the lysine pathway points out complex regulation mechanisms. FEBS Lett 487: 234-238
    • (2000) FEBS Lett , vol.487 , pp. 234-238
    • Craciun, A.1    Jacobs, M.2    Vauterin, M.3
  • 10
    • 0032558460 scopus 로고    scopus 로고
    • Allosteric activation of Arabidopsis threonine synthase by S-adenosylmethionine
    • Curien G, Job D, Douce R, Dumas R (1998) Allosteric activation of Arabidopsis threonine synthase by S-adenosylmethionine. Biochemistry 37: 13212-13221
    • (1998) Biochemistry , vol.37 , pp. 13212-13221
    • Curien, G.1    Job, D.2    Douce, R.3    Dumas, R.4
  • 11
    • 0345688035 scopus 로고    scopus 로고
    • A kinetic model of the branchpoint between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana
    • Curien G, Ravanel S, Dumas R (2003) A kinetic model of the branchpoint between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana. Eur J Biochem 270: 4615-4627
    • (2003) Eur J Biochem , vol.270 , pp. 4615-4627
    • Curien, G.1    Ravanel, S.2    Dumas, R.3
  • 12
    • 29244471699 scopus 로고    scopus 로고
    • Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms: Physiological context sets the specificity
    • Curien G, Ravanel S, Robert M, Dumas R (2005) Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms: Physiological context sets the specificity. J Biol Chem 280: 41178-41183
    • (2005) J Biol Chem , vol.280 , pp. 41178-41183
    • Curien, G.1    Ravanel, S.2    Robert, M.3    Dumas, R.4
  • 13
    • 33845651790 scopus 로고    scopus 로고
    • Allosteric monofunctional aspartate kinases from Arabidopsis
    • Curien G, Laurencin M, Robert-Genthon M, Dumas R (2007) Allosteric monofunctional aspartate kinases from Arabidopsis. FEBS J 274: 164-176
    • (2007) FEBS J , vol.274 , pp. 164-176
    • Curien, G.1    Laurencin, M.2    Robert-Genthon, M.3    Dumas, R.4
  • 16
    • 0033736521 scopus 로고    scopus 로고
    • Mechanisms to account for maintenance of the soluble methionine pool in transgenic Arabidopsis plants expressing antisense cystathionine gamma-synthase cDNA
    • Gakiere B, Ravanel S, Droux M, Douce R, Job D (2000) Mechanisms to account for maintenance of the soluble methionine pool in transgenic Arabidopsis plants expressing antisense cystathionine gamma-synthase cDNA. C R Acad Sci III 323: 841-851
    • (2000) C R Acad Sci III , vol.323 , pp. 841-851
    • Gakiere, B.1    Ravanel, S.2    Droux, M.3    Douce, R.4    Job, D.5
  • 17
    • 0036331751 scopus 로고    scopus 로고
    • Metabolic engineering of amino acids and storage proteins in plants
    • Galili G, Hofgen R (2002) Metabolic engineering of amino acids and storage proteins in plants. Metab Eng 4: 3-11
    • (2002) Metab Eng , vol.4 , pp. 3-11
    • Galili, G.1    Hofgen, R.2
  • 18
    • 0035043361 scopus 로고    scopus 로고
    • Lysine catabolism: A stress and development super-regulated metabolic pathway
    • Galili G, Tang G, Zhu X, Gakiere B (2001) Lysine catabolism: a stress and development super-regulated metabolic pathway. Curr Opin Plant Biol 4: 261-266
    • (2001) Curr Opin Plant Biol , vol.4 , pp. 261-266
    • Galili, G.1    Tang, G.2    Zhu, X.3    Gakiere, B.4
  • 19
    • 26844445269 scopus 로고    scopus 로고
    • Improving the levels of essential amino acids and sulfur metabolites in plants
    • Galili G, Amir R, Hoefgen R, Hesse H (2005) Improving the levels of essential amino acids and sulfur metabolites in plants. Biol Chem 386: 817-831
    • (2005) Biol Chem , vol.386 , pp. 817-831
    • Galili, G.1    Amir, R.2    Hoefgen, R.3    Hesse, H.4
  • 20
    • 0009912615 scopus 로고
    • In vivo regulation of threonine and isoleucine biosynthesis in Lemna paucicostata Hegelm. 6746
    • Giovanelli J, Mudd SH, Datko AH (1988) In vivo regulation of threonine and isoleucine biosynthesis in Lemna paucicostata Hegelm. 6746. Plant Physiol 86: 369-377
    • (1988) Plant Physiol , vol.86 , pp. 369-377
    • Giovanelli, J.1    Mudd, S.H.2    Datko, A.H.3
  • 21
    • 0001636206 scopus 로고
    • Regulatory structure of the biosynthetic pathway for the aspartate family of amino acids in Lemna paucicostata Hegelm. 6746, with special reference to the role of aspartokinase
    • Giovanelli J, Mudd SH, Datko AH (1989) Regulatory structure of the biosynthetic pathway for the aspartate family of amino acids in Lemna paucicostata Hegelm. 6746, with special reference to the role of aspartokinase. Plant Physiol 90: 1584-1599
    • (1989) Plant Physiol , vol.90 , pp. 1584-1599
    • Giovanelli, J.1    Mudd, S.H.2    Datko, A.H.3
  • 22
    • 33847223477 scopus 로고    scopus 로고
    • Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway
    • Goyer A, Collakova E, Shachar-Hill Y, Hanson AD (2007) Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway. Plant Cell Physiol 48: 232-242
    • (2007) Plant Cell Physiol , vol.48 , pp. 232-242
    • Goyer, A.1    Collakova, E.2    Shachar-Hill, Y.3    Hanson, A.D.4
  • 23
    • 0015904985 scopus 로고
    • Alkalization of the chloroplast stroma caused by light-dependent proton flux into the thylakoid space
    • Heldt WH, Werdan K, Milovancev M, Geller G (1973) Alkalization of the chloroplast stroma caused by light-dependent proton flux into the thylakoid space. Biochim Biophys Acta 314: 224-241
    • (1973) Biochim Biophys Acta , vol.314 , pp. 224-241
    • Heldt, W.H.1    Werdan, K.2    Milovancev, M.3    Geller, G.4
  • 24
    • 0035397515 scopus 로고    scopus 로고
    • Roles of triosephosphate isomerase and aerobic metabolism in Trypanosoma brucei
    • Helfert S, Estévez AM, Bakker B, Michels P, Clayton C (2001) Roles of triosephosphate isomerase and aerobic metabolism in Trypanosoma brucei. Biochem J 357:117-125
    • (2001) Biochem J , vol.357 , pp. 117-125
    • Helfert, S.1    Estévez, A.M.2    Bakker, B.3    Michels, P.4    Clayton, C.5
  • 25
    • 0028795414 scopus 로고
    • Threonine accumulation in a mutant of Arabidopsis thaliana (L.) Heynh. with altered aspartate kinase
    • Heremans B, Jacobs M (1995) Threonine accumulation in a mutant of Arabidopsis thaliana (L.) Heynh. with altered aspartate kinase. J Plant Physiol 146: 249-257
    • (1995) J Plant Physiol , vol.146 , pp. 249-257
    • Heremans, B.1    Jacobs, M.2
  • 26
    • 0030800564 scopus 로고    scopus 로고
    • The reversible Hill equation: How to incorporate cooperative enzymes into metabolic models
    • Hofmeyr JH, Cornish-Bowden A (1997) The reversible Hill equation: how to incorporate cooperative enzymes into metabolic models. Comp Appl Biosci (CABIOS) 13: 377-385
    • (1997) Comp Appl Biosci (CABIOS) , vol.13 , pp. 377-385
    • Hofmeyr, J.H.1    Cornish-Bowden, A.2
  • 29
    • 3843130613 scopus 로고    scopus 로고
    • Application of a high-throughput HPLC-MS/MS assay to Arabidopsis mutant screening; evidence that threonine aldolase plays a role in seed nutritional quality
    • Jander G, Norris SR, Joshi V, Fraga M, Rugg A, Yu SX, Li LL, Last RL (2004) Application of a high-throughput HPLC-MS/MS assay to Arabidopsis mutant screening; evidence that threonine aldolase plays a role in seed nutritional quality. Plant J 39: 465-475
    • (2004) Plant J , vol.39 , pp. 465-475
    • Jander, G.1    Norris, S.R.2    Joshi, V.3    Fraga, M.4    Rugg, A.5    Yu, S.X.6    Li, L.L.7    Last, R.L.8
  • 30
    • 33947493669 scopus 로고    scopus 로고
    • Two Arabidopsis threonine aldolases are nonredundant and compete with threonine deaminase for a common substrate pool
    • Joshi V, Laubengayer KM, Schauer N, Fernie AR, Jander G (2006) Two Arabidopsis threonine aldolases are nonredundant and compete with threonine deaminase for a common substrate pool. Plant Cell 18:3564-3575
    • (2006) Plant Cell , vol.18 , pp. 3564-3575
    • Joshi, V.1    Laubengayer, K.M.2    Schauer, N.3    Fernie, A.R.4    Jander, G.5
  • 32
    • 0013617318 scopus 로고
    • Energetics of intact chloroplasts
    • Barber J ed, pp, The Netherlands: Elsevier/North-Holland Biomedical Press
    • Krause GH, Heber U (1976) Energetics of intact chloroplasts. In The intact chloroplast. Barber J (ed), pp 174-175. The Netherlands: Elsevier/North-Holland Biomedical Press
    • (1976) The intact chloroplast , pp. 174-175
    • Krause, G.H.1    Heber, U.2
  • 33
    • 0021741048 scopus 로고
    • The branch point effect: Ultrasensitivity and subsensitivity to metabolic control
    • LaPorte DC, Walsh K, Koshland DE Jr (1984) The branch point effect: ultrasensitivity and subsensitivity to metabolic control. J Biol Chem 259:14068-14075
    • (1984) J Biol Chem , vol.259 , pp. 14068-14075
    • LaPorte, D.C.1    Walsh, K.2    Koshland Jr, D.E.3
  • 34
    • 0030980668 scopus 로고    scopus 로고
    • The GLYl gene of Saccharomyces cerevisiae encodes a low-specific L-threonine aldolase that catalyzes cleavage of L-allo-threonine and L-threonine to glycine. Expression of the gene in Escherichia coli and purification and characterization of the enzyme
    • Liu J, Nagata S, Dairi T, Misono H, Shimizu S, Yamada H (1997) The GLYl gene of Saccharomyces cerevisiae encodes a low-specific L-threonine aldolase that catalyzes cleavage of L-allo-threonine and L-threonine to glycine. Expression of the gene in Escherichia coli and purification and characterization of the enzyme. Eur J Biochem 245:289-293
    • (1997) Eur J Biochem , vol.245 , pp. 289-293
    • Liu, J.1    Nagata, S.2    Dairi, T.3    Misono, H.4    Shimizu, S.5    Yamada, H.6
  • 35
    • 0034047474 scopus 로고    scopus 로고
    • Purification and characterization of bifunctional lysine-ketoglutarate reductase/ saccharopine dehydrogenase from developing soybean seeds
    • Miron D, Ben-Yaacov S, Reches D, Schupper A, Galili G (2000) Purification and characterization of bifunctional lysine-ketoglutarate reductase/ saccharopine dehydrogenase from developing soybean seeds. Plant Physiol 123: 655-664
    • (2000) Plant Physiol , vol.123 , pp. 655-664
    • Miron, D.1    Ben-Yaacov, S.2    Reches, D.3    Schupper, A.4    Galili, G.5
  • 36
    • 0028191564 scopus 로고
    • Genetic and amino acid analysis of two maize threonine overproducing, lysine-insensitive aspartate kinase mutants
    • Muehlbauer GJ, Gengenbach BG, Somers DA, Donovan CM (1994) Genetic and amino acid analysis of two maize threonine overproducing, lysine-insensitive aspartate kinase mutants. Theor Appl Genet 89: 767-774
    • (1994) Theor Appl Genet , vol.89 , pp. 767-774
    • Muehlbauer, G.J.1    Gengenbach, B.G.2    Somers, D.A.3    Donovan, C.M.4
  • 37
    • 0030939285 scopus 로고    scopus 로고
    • Effects of expressing E. coli threonine synthase in tobacco (Nicotiana tabacum L.) suspension culture cells on free amino acid levels, aspartate pathway enzyme activities and uptake of aspartate into the cells
    • Muhitch MJ (1997) Effects of expressing E. coli threonine synthase in tobacco (Nicotiana tabacum L.) suspension culture cells on free amino acid levels, aspartate pathway enzyme activities and uptake of aspartate into the cells. J Plant Physiol 150:16-22
    • (1997) J Plant Physiol , vol.150 , pp. 16-22
    • Muhitch, M.J.1
  • 38
    • 0033567930 scopus 로고    scopus 로고
    • Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: Computer simulation and metabolic control analysis
    • Mulquiney PJ, Kuchel PW (1999) Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: computer simulation and metabolic control analysis. Biochem J 342: 597-604
    • (1999) Biochem J , vol.342 , pp. 597-604
    • Mulquiney, P.J.1    Kuchel, P.W.2
  • 39
    • 0035996723 scopus 로고    scopus 로고
    • Overproduction, purification, and characterization of recombinant aspartate semialdehyde dehydrogenase from Arabidopsis thaliana
    • Paris S, Wessel PM, Dumas R (2002a) Overproduction, purification, and characterization of recombinant aspartate semialdehyde dehydrogenase from Arabidopsis thaliana. Protein Expression Purif 24: 99-104
    • (2002) Protein Expression Purif , vol.24 , pp. 99-104
    • Paris, S.1    Wessel, P.M.2    Dumas, R.3
  • 40
    • 0035996735 scopus 로고    scopus 로고
    • Overproduction, purification, and characterization of recombinant bifunctional threonine-sensitive aspartate kinase-homoserine dehydrogenase from Arabidopsis thaliana
    • Paris S, Wessel PM, Dumas R (2002b) Overproduction, purification, and characterization of recombinant bifunctional threonine-sensitive aspartate kinase-homoserine dehydrogenase from Arabidopsis thaliana. Protein Expression Purif 24:105-110
    • (2002) Protein Expression Purif , vol.24 , pp. 105-110
    • Paris, S.1    Wessel, P.M.2    Dumas, R.3
  • 41
    • 0038475950 scopus 로고    scopus 로고
    • Mechanism of control of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase by threonine
    • Paris S, Viemon C, Curien G, Dumas R (2003) Mechanism of control of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase by threonine. J Biol Chem 278: 5361-5366
    • (2003) J Biol Chem , vol.278 , pp. 5361-5366
    • Paris, S.1    Viemon, C.2    Curien, G.3    Dumas, R.4
  • 43
    • 0032522761 scopus 로고    scopus 로고
    • Cystathionine gamma-synthase from Arabidopsis thaliana: Purification and biochemical characterization of the recombinant enzyme overexpressed in Escherichia coli
    • Ravanel S, Gakiere B, Job D, Douce R (1998) Cystathionine gamma-synthase from Arabidopsis thaliana: purification and biochemical characterization of the recombinant enzyme overexpressed in Escherichia coli. Biochem J 331: 639-648
    • (1998) Biochem J , vol.331 , pp. 639-648
    • Ravanel, S.1    Gakiere, B.2    Job, D.3    Douce, R.4
  • 44
    • 33750315393 scopus 로고    scopus 로고
    • Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses
    • Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S (2006) Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses. Proc Natl Acad Sci USA 103:15687-15692
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 15687-15692
    • Rebeille, F.1    Jabrin, S.2    Bligny, R.3    Loizeau, K.4    Gambonnet, B.5    Van Wilder, V.6    Douce, R.7    Ravanel, S.8
  • 45
    • 0021304602 scopus 로고
    • Potassium, sodium, and chloride content of isolated intact chloroplasts in relation to ionic compartmentation in leaves
    • Robinson SP, Downton WJ (1984) Potassium, sodium, and chloride content of isolated intact chloroplasts in relation to ionic compartmentation in leaves. Arch Biochem Biophys 228:197-206
    • (1984) Arch Biochem Biophys , vol.228 , pp. 197-206
    • Robinson, S.P.1    Downton, W.J.2
  • 46
    • 0000641223 scopus 로고
    • Photosynthetic carbon reduction cycle
    • Hatch MD, Boardman NK eds, New York: Academic Press
    • Robinson SP, Walker DA (1981) Photosynthetic carbon reduction cycle. In The Biochemistry of plants: a Comprehensive Treatise, Hatch MD, Boardman NK (eds), Vol. 8, pp 193-236. New York: Academic Press
    • (1981) The Biochemistry of plants: A Comprehensive Treatise , vol.8 , pp. 193-236
    • Robinson, S.P.1    Walker, D.A.2
  • 47
    • 0018948321 scopus 로고
    • S-adenosylmethionine - a novel regulator of aspartate kinase
    • Rognes SE, Lea PJ, Miflin BJ (1980) S-adenosylmethionine - a novel regulator of aspartate kinase. Nature 287: 357-359
    • (1980) Nature , vol.287 , pp. 357-359
    • Rognes, S.E.1    Lea, P.J.2    Miflin, B.J.3
  • 48
    • 0347928655 scopus 로고    scopus 로고
    • Transcriptional and biochemical regulation of a novel Arabidopsis thaliana bifunctional aspartate kinase-homoserine dehydrogenase gene isolated by functional complementation of a yeast hom6 mutant
    • Rognes SE, Dewaele E, Aas SF, Jacobs M, Frankard V (2003) Transcriptional and biochemical regulation of a novel Arabidopsis thaliana bifunctional aspartate kinase-homoserine dehydrogenase gene isolated by functional complementation of a yeast hom6 mutant. Plant Mol Biol 51: 281-294
    • (2003) Plant Mol Biol , vol.51 , pp. 281-294
    • Rognes, S.E.1    Dewaele, E.2    Aas, S.F.3    Jacobs, M.4    Frankard, V.5
  • 49
    • 0037113867 scopus 로고    scopus 로고
    • The metabolic architecture of plant cells. Stability of central metabolism and flexibility of anabolic pathways during the growth cycle of tomato cells
    • Rontein D, Dieuaide-Noubhani M, Dufourc EJ, Raymond P, Rolin D (2002) The metabolic architecture of plant cells. Stability of central metabolism and flexibility of anabolic pathways during the growth cycle of tomato cells. J Biol Chem 277: 43948-43960
    • (2002) J Biol Chem , vol.277 , pp. 43948-43960
    • Rontein, D.1    Dieuaide-Noubhani, M.2    Dufourc, E.J.3    Raymond, P.4    Rolin, D.5
  • 50
    • 0016201107 scopus 로고
    • Optimal design of feedback control by inhibition: Steady state considerations
    • Savageau MA (1974) Optimal design of feedback control by inhibition: steady state considerations. J Molec Evol 4: 139-156
    • (1974) J Molec Evol , vol.4 , pp. 139-156
    • Savageau, M.A.1
  • 51
    • 0016160429 scopus 로고
    • Measurement of protein by spectroscopy at 205 nm
    • Scopes RK (1974) Measurement of protein by spectroscopy at 205 nm. Anal Biochem 59: 277-282
    • (1974) Anal Biochem , vol.59 , pp. 277-282
    • Scopes, R.K.1
  • 52
    • 0036008585 scopus 로고    scopus 로고
    • High free-methionine and decreased lignin content result from a mutation in the Arabidopsis S-adenosyl-L- methionine synthetase 3 gene
    • Shen B, Li C, Tarczynski MC (2002) High free-methionine and decreased lignin content result from a mutation in the Arabidopsis S-adenosyl-L- methionine synthetase 3 gene. Plant J 29: 371-380
    • (2002) Plant J , vol.29 , pp. 371-380
    • Shen, B.1    Li, C.2    Tarczynski, M.C.3
  • 53
    • 0033150123 scopus 로고    scopus 로고
    • Enhanced expression and activation of the alternative oxidase during infection of Arabidopsis with Pseudomonas syringae pv tomato
    • Simons BH, Millenaar FF, Mulder L, Van Loon LC, Lambers H (1999) Enhanced expression and activation of the alternative oxidase during infection of Arabidopsis with Pseudomonas syringae pv tomato. Plant Physiol 120: 529-538
    • (1999) Plant Physiol , vol.120 , pp. 529-538
    • Simons, B.H.1    Millenaar, F.F.2    Mulder, L.3    Van Loon, L.C.4    Lambers, H.5
  • 55
    • 0345392613 scopus 로고    scopus 로고
    • Synthesis of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is concertedly regulated by metabolic and stress-associated signals
    • Stepansky A, Galili G (2003) Synthesis of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is concertedly regulated by metabolic and stress-associated signals. Plant Physiol 133:1407-1415
    • (2003) Plant Physiol , vol.133 , pp. 1407-1415
    • Stepansky, A.1    Galili, G.2
  • 56
    • 0017831488 scopus 로고
    • The role of isozymes in metabolism: A model of metabolic pathways as the basis for the biological role of isozymes
    • Ureta T (1978) The role of isozymes in metabolism: a model of metabolic pathways as the basis for the biological role of isozymes. Curr Top Cell Regul 13: 233-258
    • (1978) Curr Top Cell Regul , vol.13 , pp. 233-258
    • Ureta, T.1
  • 57
    • 0020016147 scopus 로고
    • The comparative isoenzymology of vertebrate hexokinases
    • Ureta T (1982) The comparative isoenzymology of vertebrate hexokinases. Comp Biochem Physiol B 71: 549-555
    • (1982) Comp Biochem Physiol B , vol.71 , pp. 549-555
    • Ureta, T.1
  • 58
    • 34547654118 scopus 로고    scopus 로고
    • Kinetic model of sucrose accumulation in maturing sugarcane culm tissue
    • Uys L, Botha FC, Hofmeyr JH, Rohwer JM (2007) Kinetic model of sucrose accumulation in maturing sugarcane culm tissue. Phytochemistry 68: 2375-2392
    • (2007) Phytochemistry , vol.68 , pp. 2375-2392
    • Uys, L.1    Botha, F.C.2    Hofmeyr, J.H.3    Rohwer, J.M.4
  • 59
    • 0034642216 scopus 로고    scopus 로고
    • Evidence for two distinct effector-binding sites in threonine deaminase by site-directed mutagenesis, kinetic, and binding experiments
    • Wessel PM, Graciet E, Douce R, Dumas R (2000) Evidence for two distinct effector-binding sites in threonine deaminase by site-directed mutagenesis, kinetic, and binding experiments. Biochemistry 39: 15136-15143
    • (2000) Biochemistry , vol.39 , pp. 15136-15143
    • Wessel, P.M.1    Graciet, E.2    Douce, R.3    Dumas, R.4
  • 60
    • 0000957432 scopus 로고
    • Subcellular volumes and metabolite concentrations in barley leaves
    • Winter H, Robinson DG, Heldt HW (1994a) Subcellular volumes and metabolite concentrations in barley leaves. Planta 191: 180-190
    • (1994) Planta , vol.191 , pp. 180-190
    • Winter, H.1    Robinson, D.G.2    Heldt, H.W.3
  • 61
    • 0027976083 scopus 로고
    • Subcellular volumes and metabolite concentrations in spinach leaves
    • Winter H, Robinson DG, Heldt HW (1994b) Subcellular volumes and metabolite concentrations in spinach leaves. Planta 193: 530-535
    • (1994) Planta , vol.193 , pp. 530-535
    • Winter, H.1    Robinson, D.G.2    Heldt, H.W.3
  • 62
    • 15744391433 scopus 로고    scopus 로고
    • A mathematical model for the branched chain amino acid biosynthetic pathways of Escherichia coli K12
    • Yang CR, Shapiro BE, Hung SP, Mjolsness ED, Hatfield GW (2005) A mathematical model for the branched chain amino acid biosynthetic pathways of Escherichia coli K12. J Biol Chem 280: 11224-11232
    • (2005) J Biol Chem , vol.280 , pp. 11224-11232
    • Yang, C.R.1    Shapiro, B.E.2    Hung, S.P.3    Mjolsness, E.D.4    Hatfield, G.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.