Biological safety of liposome-fullerene consisting of hydrogenated lecithin, glycine soja sterols, and fullerene-C60 upon photocytotoxicity and bacterial reverse mutagenicity

Toxicology and Industrial Health

Volumn 25, Issue 3, 2009, Pages 197-203

  Kato, S ^a   Aoshima, H ^b   Saitoh, Y ^a   Miwa, N ^a  

^a PREFECTURAL UNIVERSITY OF HIROSHIMA   (Japan)

^b Vitamin C60 BioResearch Corporation   (Japan)

Author keywords

bacterial reverse mutagenicity; fullerene; liposome; photocytotoxicity

Indexed keywords

2 AMINOANTHRACENE; 2 NITROFLUORENE; AMINOACRIDINE; FULLERENE; GLYCINE; HISTIDINE; LIPOSOME; N ETHYL NA' NITRO N NITROSOGUANIDINE; NANOPARTICLE; NITROSOGUANIDINE; PHOSPHATIDYLCHOLINE; REACTIVE OXYGEN METABOLITE; SODIUM AZIDE; SOYBEAN OIL; STEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ESCHERICHIA COLI; FIBROBLAST; GROWTH INHIBITION; MOUSE; MUTAGENICITY; MUTATIONAL ANALYSIS; NONHUMAN; PHOTOTOXICITY; RISK ASSESSMENT; ROOM TEMPERATURE; ULTRAVIOLET A RADIATION;

CARBOXYLIC ACIDS; CELL SURVIVAL; FULLERENES; GLYCINE; LECITHINS; LIPOSOMES; MUTAGENICITY TESTS; SOYBEAN OIL; STEROLS; ULTRAVIOLET RAYS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; GLYCINE MAX; GLYCINE SOJA; SALMONELLA TYPHIMURIUM;

EID: 67149115131     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1177/0748233709106186     Document Type: Article

References (26)

1. Babynin EV, Nuretdinov IA, Gubskaia VP, Barabanshikov BI (2002) Study of mutagenic activity of fullerene and some of its derivatives using His+ reverations of Salmonella typhimurium as an example. Genetika 38: 453–457.
2. Claxton LD, Allen J, Auletta A, Mortelmams K, Nestmann E, Zeiger E (1987) Guide for the Salmonella typhimurium/mammalian microscope tests for bacterial mutagenicity. Mutat Res 189: 83–91.
3. Hotze EM, Labille J, Alvarez P, Wiesner MR (2008) Mechanisms of photochemistry and reactive oxygen production by fullerene suspensions in water. Environ Sci Technol 42: 4175–4180.
4. Hung CF, Chen JK, Liao MH, Lo HM, Fang JY (2006) Development and evaluation of emulsion-liposome blends for reverastrol delivery. J Nanosci Nanotechnol 6: 2950–2958.
5. Ikeda A, Doi Y, Nishiguchi K, Kitamura K, Hashizume M, Kikuchi J (2007) Induction of cell death by photodynamic therapy with water-soluble lipid-membrane-incorporated [60] fullerene. Org Biomol Chem 5: 1158–1160.
6. Jacobsen NR, Pojana G, White P, Møller P, Cohn CA, Korsholm KS (2008) Genotoxicity, cytotoxicity, and reactive oxygen species induced by single-walled carbon nanotubes and C(60) fullerenes in the FE1-Mutatrade markMouse lung epithelial cells. Environ Mol Mutagen 49: 476–487.
7. Jiang W, Kim BY, Rutka JT, Chan WC (2007) Advances and challenges of nanotrchnology-based drug delivery systems. Expert Opin Drug Deliv 4: 621–633.
8. Kamat JP, Devasagayam TP, Priyadarsini KI, Mohan H (2000) Reactive oxygen species mediated membrane damage induced by fullerene derivatives and its possible biological implications. Toxicology 155: 55–61.
9. Kolosnjaj J, Szwarc H, Moussa F (2007) Toxicity studies of fullerenes and derivatives. Adv Exp Med Biol 620: 168–180.
10. Lee J, Fortner JD, Hughes JB, Kim JH (2007) Photochemical production of reactive oxygen species by C60 in the aqueous phase during UV irradiation. Environ Sci Technol 41: 2529–2535.
11. Lee J, Yamakoshi Y, Hughes JB, Kim JH (2008) Mechanism of C60 photoactivity in water: fate of triplet state and radical anion and production of reactive oxygen species. Environ Sci Technol 42: 3459–3464.
12. Maron DM, Ames BN (1983) Revised methods for the Salmonella mutagenicity test. Mutat Res 113: 173–215.
13. Mori T, Takada H, Ito S, Matsubayashi K, Miwa N, Sawaguchi T (2006) Preclinical studies on safety of fullerene upon acute oral administration and evaluation for no mutagenesis. Toxicology 225: 48–54.
14. Nelson MA, Domann FE, Bowden GT, Hooser SB, Fernando O, Carter DE (1993) Effects of acute and subchronic exposure of topically applied fullerene extracts on the mouse skin. Toxicol Ind Health 9: 623–630.
15. Nielsen GD, Roursgaad M, Jensen KA, Poulsen SS, Larsen ST (2008) In vivo biology and toxicology of fullerenes and their derivatives. Basic Clin Pharmacol Toxicol 103: 197–208.
16. Pryluts'ka SV, Hryniuk II, Burlaka AP, Holub OA, Matyshevs'ka OP (2006) Oxidative properties of photoexcited fullerenes C60 and C60-containing composites in suspension of thymocytes and Ehrlich ascites carcinoma cells. Ukr Biokhim Zh 78: 139–145.
17. Raicu P, Mixich F (1992) Cytogenetic effects of sodium azide encapsulated in liposomes on heteroploid cell cultures. Mutat Res 283: 215–219.
18. Sera N, Tokiwa H, Miyata N (1996) Mutagenicity of the fullerene C60-generated singlet oxygen dependent formation of lipid peroxides. Carcinogenesis 17: 2163–2169.
19. Trotta M, Peira E, Carlotti ME, Gallarate M (2004) Deformable liposomes for dermal administration of methotrexate. Int J Pharm 270: 119–125.
20. Valenta C, Wanka M, Heidlas J (2000) Evaluation of novel soya-lecithin formulations for dermal use containing ketoprofen as a model drug. J Control Release 63: 165–173.
21. Wang IC, Tai LA, Lee DD, Kanakamma PP, Shen CK, Luh TY (1999) C60 and water-soluble fullerene derivatives as antioxidants against radical-initiated lipid peroxidation. J Med Chem 42: 4614–4620.
22. Xiao L, Matsubayashi K, Miwa N (2007) Inhibitory effect of the water-soluble polymer-wrapped derivative of fullerene on UVA-induced melanogenesis via downregulation of tyrosinase expression in human melanocytes and skin tissues. Arch Dermatol Res 299: 245–257.
23. Xiao L, Takada H, Gan X, Miwa N (2006) The water-soluble fullerene derivative “Radical Sponge” exerts cytoprotective action against UVA irradiation but not visible-light-catalyzed cytotoxicity in human skin keratinocytes. Bioorg Med Chem Lett 16: 1590–1595.
24. Xiao L, Takada H, Maeda K, Haramoto M, Miwa N (2005) Antioxidant effects of water-soluble fullerene derivatives against ultraviolet ray or peroxylipid through their action of scavenging the reactive oxygen species in human skin keratinocytes. Biomed Pharmacother 59: 351–358.
25. Yahagi T, Nagao M, Seino Y, Matsushima T, Sugimura T, Okada M (1977) Mutagenecities of N-nitrosamines of Salmonella. Mutat Res 48: 121–129.
26. Zhao B, He YY, Bilski PJ, Chignell CF (2008) Pristine (C60) and hydroxylated [C60(OH)24] fullerene phototoxicity towards HaCaT keratinocytes: type 1 vs type II mechanisms. Chem Res Toxicol 21: 1056–1063.