NF-κB inhibitory activities of the methanol extracts and some constituents therein of some Vietnamese medicinal plants

Scientia Pharmaceutica

Volumn 77, Issue 2, 2009, Pages 389-399

  Nam, Nguyen H ^a   Jae, You Y ^b  

^a HANOI UNIVERSITY OF PHARMACY   (Viet Nam)

^b University of South Dakota   (United States)

Author keywords

Medicinal plants; NF B inhibitory activity; Screening

Indexed keywords

CRINUM LATIFOLIUM EXTRACT; DRUG METABOLITE; EVODIA RUTAECARPA EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHANOL; PERILLA OCYMOIDES EXTRACT; PLANT EXTRACT; POLYGONUM CUSPIDATUM EXTRACT; RUBIA CORDIFOLIA EXTRACT; SCUTELLARIA BARBATA EXTRACT; SPARGANIUM STENOPHYLLUM EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG SCREENING; FRUIT; MEDICINAL PLANT; MOUSE; NONHUMAN; PLANT LEAF; RHIZOME;

EID: 67149093758     PISSN: 00368709     EISSN: 22180532     Source Type: Journal    
DOI: 10.3797/scipharm.0903-15     Document Type: Article

References (16)

1. Zingarelli B, Sheehan M, Wong HR. Nuclear factor-κB as a therapeutic target in critical care medicine. Crit Care Med. 2003; 31 (Suppl 1): S105-S111. doi:10.1097/00003246-200301001-200400015 (Pubitemid 36143484)
2. Koo TH, Lee JH, Park YJ, Hong YS, Kim HS, Kim KW, Lee JJ. A Sesquiterpene Lactone, Costunolide, from Magnolia grandiflora Inhibits NF-κB by Targeting IkB Phosphorylation. Planta Med. 2001; 67: 103-107. doi:10.1055/s-2001-11503
3. Hwang BY, Lee JH, Nam JB, Hong YS, Lee JJ. Lignans from Saururus chinensis inhibiting the transcription factor NF-κB. Phytochemistry. 2003; 64: 765-771. doi:10.1016/S0031-9422(03)00391-401
4. Hwang BY, Lee JH, Koo TH, Kim HS, Hong YS, Ro JS, Lee KS, Lee JJ. Kaurane Diterpenes from Isodon japonicus Inhibit Nitric Oxide and Prostaglandin E2 Production and NF-κB Activation in LPS-Stimulated Macrophage RAW264.7 Cells. Planta Med. 2001; 67: 406-410. doi:10.1055/s-2001-15808
5. Jin HZ, Hwang BY, Kim HS, Lee JH, Kim YH, Lee JJ. Antiinflammatory Constituents of Celastrus orbiculatus inhibit the NF-κB Activation and NO Production. J Nat Prod. 2002; 65: 89-91. doi:10.1021/np010428r
6. Chaicharoenpong C, Kato K, Umezawa K. Synthesis and Structure-Activity Relationship of Dehydromethylepoxyquinomicin Analogues as Inhibitors of NF-κB Functions. Bioorg Med Chem. 2002; 10: 3933-3939. doi:10.1016/S0968-0896(02)00315-322 (Pubitemid 36164692)
7. Shotwell JB, Koh B, Choi HW, Wood JL, Crews CM. Inhibitors of NF-±B Signalling: Design and Synthesis of a Biotinylated Isopropanepoxydone Affinity Reagent. Bioorg Med Chem. 2002; 12: 3463-3466. doi:10.1016/S0960-894X(02)00769-772 (Pubitemid 35292470)
8. Takada Y, Kobayashi Y, Aggarwal BB. Evodiamine abolishes constitutive and inducible NF-κB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-κB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion. J Biol Chem. 2005; 280: 17203-17212. doi:10.1074/jbc.M500077200 (Pubitemid 41509418)
9. Nam NH, Chung LH. [Isolation of resveratrol and emodin from Polygonum cuspidatum growing in Vietnam.] Tap Chi Duoc Hoc [Pharm J Hanoi]. 2007; 7-10.
10. Tuan ND, Nam NH, Vung NT. [Quantitation of resveratrol content in Polygonum cuspidatum growing in Vietnam.] Tap Chi Duoc Hoc [Pharm J Hanoi]. 2007; 13-16.
11. Nam NH, Vung NT. [Isolation of some bioactive compounds from Perilla ocymoides.] Tap Chi Duoc Lieu [J Med Mater Hanoi]. 2008; 13: 120-123.
12. Nam NH. Naturally Occuring NF-κB Inhibitors. Mini Rev Med Chem. 2006; 6: 945-951. doi:10.2174/138955706777934937
13. Nam NH, You YJ, Kim Y, Hong DH, Kim HM, Ahn BZ. New Contituents from Crinum latifolium with Inhibitory Activity against Tube-like Formation of Human Umbilical Endothelial Cells. Nat Prod Res. 2004; 18: 485-491. doi:10.1080/1057563031000122103
14. Nam NH, Vung NT. [Isolation and structural elucidation of two flavonoids from Crinum latifolium.] Tap Chi Duoc Hoc [Pharm J Hanoi]. 2006; 7-9.
15. Erkel G, Anke T, Sterner O. Inhibition of NF-kappa B activation by panepoxydone. Biochem Biophys Res Com. 1996; 226: 214-221. doi:10.1006/bbrc. 1996.1335
16. Skehan P, Storeng R, Scudiero D, Monk A, MacMahon J, Vistica D, Warren J, Bokesch H, Kenny S, Boyd MR. New colorimetric cytotoxicity assay for anticancer drug screening. J Natl Cancer Inst. 1990; 82: 1107-1112. doi:10.1093/jnci/82. 13.1107 (Pubitemid 20213250)