Simulating the growth of articular cartilage explants in a permeation bioreactor to aid in experimental protocol design

Journal of Biomechanical Engineering

Volumn 131, Issue 4, 2009, Pages

  Ficklin, Timothy P ^a   Davol, Andrew ^a   Klisch, Stephen M ^a  

^a CALIFORNIA POLYTECHNIC STATE UNIVERSITY   (United States)

Author keywords

Bioreactor; Cartilage; Finite element analysis; Growth; Mixture; Permeation

Indexed keywords

ARTICULAR CARTILAGES; BIOCHEMICAL PARAMETERS; BOVINE ARTICULAR CARTILAGE; CARTILAGE GROWTH; EXPERIMENTAL DESIGN; EXPERIMENTAL PROTOCOLS; FINITE ELEMENT; FINITE ELEMENT ANALYSIS; FINITE ELEMENT MODELS; GROWTH; GROWTH BOUNDARIES; GROWTH LAWS; IN-VITRO; MAXIMUM SHEAR STRESS; MECHANICAL STIMULUS; NON-HOMOGENEOUS; NON-LINEAR FINITE ELEMENT MODEL; PERMEATION VELOCITY; PILOT EXPERIMENT; POROELASTIC; PROTEOGLYCANS; SOLID MATRIXES; TIME-DEPENDENT; TISSUE SPECIMENS;

BIOCONVERSION; BIOMECHANICS; BIOREACTORS; CARTILAGE; CONSTITUTIVE EQUATIONS; EXPERIMENTS; LIGAMENTS; SHEAR STRESS; STRENGTH OF MATERIALS; ULTRASONIC MEASUREMENT;

FINITE ELEMENT METHOD;

ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BIOREACTOR; CATTLE; CONTROLLED STUDY; EXPERIMENTAL DESIGN; EXPLANT; FINITE ELEMENT ANALYSIS; NONHUMAN; SIMULATION; TISSUE GROWTH; ANIMAL; BIOLOGICAL MODEL; BIOMECHANICS; COMPUTER SIMULATION; ELASTICITY; GROWTH, DEVELOPMENT AND AGING; MECHANICAL STRESS; MECHANOTRANSDUCTION; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; POROSITY;

BOVINAE;

COLLAGEN; PROTEOGLYCAN;

ANIMALS; BIOMECHANICS; BIOREACTORS; CARTILAGE, ARTICULAR; CATTLE; COLLAGEN; COMPUTER SIMULATION; ELASTICITY; FINITE ELEMENT ANALYSIS; MECHANOTRANSDUCTION, CELLULAR; MODELS, BIOLOGICAL; ORGAN CULTURE TECHNIQUES; POROSITY; PROTEOGLYCANS; STRESS, MECHANICAL;

EID: 67049169378     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.3049856     Document Type: Article

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