Germline variations of the MALT1 gene as risk factors in the development of primary gastric B-cell lymphoma

European Journal of Cancer

Volumn 45, Issue 10, 2009, Pages 1865-1870

  Hellmig, Stephan ^a   Bartscht, Tobias ^a   Fischbach, Wolfgang ^b   Ott, Stephan Johannes ^a   Rosenstiel, Philip ^c   Klapper, Wolfram ^a   Fölsch, Ulrich Robert ^a   Schreiber, Stefan ^a,c  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b KLINIKUM ASCHAFFENBURG   (Germany)

^c UNIVERSITY OF KIEL   (Germany)

Author keywords

Gastric B cell lymphoma; Genetic susceptibility; MALT1

Indexed keywords

ADULT; AGED; ARTICLE; B CELL LYMPHOMA; BLOOD DONOR; CANCER GRADING; CANCER RISK; CARCINOGENESIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LOCUS; GENE SEQUENCE; GENE STRUCTURE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HELICOBACTER INFECTION; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MALT1 GENE; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; MULTICENTER STUDY; MUTATOR GENE; PRIMARY TUMOR; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STOMACH LYMPHOMA;

ADULT; AGED; CASPASES; FEMALE; GASTRITIS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GERM-LINE MUTATION; HAPLOTYPES; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; LINKAGE DISEQUILIBRIUM; LYMPHOMA, B-CELL, MARGINAL ZONE; MALE; MIDDLE AGED; NEOPLASM PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; STOMACH NEOPLASMS;

EID: 67049100458     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2009.03.010     Document Type: Article

References (34)

1. Isaacson P., and Wright D.H. Extranodal malignant lymphoma arising from mucosa-associated lymphoid tissue. Cancer 53 11 (1984) 2515-2524
2. Jaffe E.S. Common threads of mucosa-associated lymphoid tissue lymphoma pathogenesis: from infection to translocation. J Natl Cancer Inst 96 8 (2004) 571-573
3. Parsonnet J., Hansen S., Rodriguez L., et al. Helicobacter pylori infection and gastric lymphoma. New Engl J Med 330 18 (1994) 1267-1271
4. Farinha P., and Gascoyne R.D. Helicobacter pylori and MALT lymphoma. Gastroenterology 128 6 (2005) 1579-1605
5. Akagi T., Motegi M., Tamura A., et al. A novel gene, MALT1 at 18q21, is involved in t(11;18)(q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue. Oncogene 18 42 (1999) 5785-5794
6. Guo B., Su T.T., and Rawlings D.J. Protein kinase C family functions in B-cell activation. Curr Opin Immunol 16 3 (2004) 367-373
7. Dierlamm J., Baens M., Wlodarska I., et al. The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas. Blood 93 11 (1999) 3601-3609
8. Liu H., Ruskon-Fourmestraux A., Lavergne-Slove A., et al. Resistance of t(11;18) positive gastric mucosa-associated lymphoid tissue lymphoma to Helicobacter pylori eradication therapy. Lancet 357 9249 (2001) 39-40
9. Crabtree J.E., and Spencer J. Immunologic aspects of Helicobacter pylori infection and malignant transformation of B cells. Semin Gastrointest Dis 7 1 (1996) 30-40
10. de Jong D., van der Hulst R.W., Pals G., et al. Gastric non-Hodgkin lymphomas of mucosa-associated lymphoid tissue are not associated with more aggressive Helicobacter pylori strains as identified by CagA. Am J Clin Pathol 106 5 (1996) 670-675
11. Hemminki K., Sundquist J., and Ji J. Familial risk for gastric carcinoma: an updated study from Sweden. Brit J Cancer 96 8 (2007) 1272-1277
12. Malaty H.M., Engstrand L., Pedersen N.L., and Graham D.Y. Helicobacter pylori infection: genetic and environmental influences. A study of twins. Ann Intern Med 120 12 (1994) 982-986
13. El-Omar E.M., Carrington M., Chow W.H., et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 404 6776 (2000) 398-402
14. Hellmig S., Fischbach W., and Goebeler-Kolve M.E. A functional promotor polymorphism of TNF-alpha is associated with primary gastric B-Cell lymphoma. Am J Gastroenterol 100 12 (2005) 2644-2649
15. Rosenstiel P., Hellmig S., Hampe J., et al. Influence of polymorphisms in the NOD1/CARD4 and NOD2/CARD15 genes on the clinical outcome of Helicobacter pylori infection. Cell Microbiol 8 7 (2006) 1188-1198
16. Fischbach W., Dragosics B., Kolve-Goebeler M.E., et al. Primary gastric B-cell lymphoma: results of a prospective multicenter study. The German-Austrian Gastrointestinal Lymphoma Study Group. Gastroenterology 119 5 (2000) 1191-1202
17. Lewin K.J., Ranchod M., and Dorfman R.F. Lymphomas of the gastrointestinal tract: a study of 117 cases presenting with gastrointestinal disease. Cancer 42 2 (1978) 693-707
18. Carbone P.P., Kaplan H.S., Musshoff K., et al. Report of the Committee on Hodgkin's Disease Staging Classification [Clinical staging classification of non-Hodgkin's lymphomas (author's transl)]. Gastrointestinal malignant lymphomas of the mucosa-associated lymphoid tissue: factors relevant to prognosis. Lymphomas of the gastrointestinal tract: a study of 117 cases presenting with gastrointestinal disease. Cancer Res 31 11 (1971) 1860-1861
19. Musshoff K. Clinical staging classification of non-Hodgkin's lymphomas (author's transl). Strahlentherapie 153 4 (1977) 218-221
20. Radaszkiewicz T., Dragosics B., and Bauer P. Gastrointestinal malignant lymphomas of the mucosa-associated lymphoid tissue: factors relevant to prognosis. Gastroenterology 102 5 (1992) 1628-1638
21. Hampe J., Wollstein A., Lu T., Frevel H.J., Will M., Manaster C., et al. An integrated system for high throughput TaqMan based SNP genotyping. Bioinformatics 17 7 (2001) 654-655
22. Kruglyak L., Daly M.J., Reeve-Daly M.P., and Lander E.S. Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Human Genet 58 6 (1996) 1347-1363
23. Krawczak M., Konecki D.S., Schmidtke J., Duck M., Engel W., Nutzenadel W., et al. Allelic association of the cystic fibrosis locus and two DNA markers, XV2c and KM19, in 55 German families. Human Genet 80 1 (1988) 78-80
24. Devlin B., and Risch N. A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics 29 2 (1995) 311-322
25. Fischbach W. Gastrointestinal lymphomas. Z Gastroenterol 42 9 (2004) 1067-1072
26. Wang D., Matsumoto R., You Y., et al. CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1. Mol Cell Biol 24 1 (2004) 164-171
27. van Oers N.S., and Chen Z.J. Cell biology. Kinasing and clipping down the NF-kappa B trail. Science 308 5718 (2005) 65-66
28. Sanchez-Izquierdo D., Buchonnet G., Siebert R., et al. MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma. Blood 101 11 (2003) 4539-4546
29. Nakagawa M., Hosokawa Y., Yonezumi M., et al. MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10. Blood 106 13 (2005) 4210-4216
30. Sagaert X., Laurent M., Baens M., Wlodarska I., and De Wolf-Peeters C. MALT1 and BCL10 aberrations in MALT lymphomas and their effect on the expression of BCL10 in the tumour cells. Mod Pathol 19 2 (2006) 225-232
31. Baens M., Steyls A., Dierlamm J., De Wolf-Peeters C., and Marynen P. Structure of the MLT gene and molecular characterization of the genomic breakpoint junctions in the t(11;18)(q21;q21) of marginal zone B-cell lymphomas of MALT type. Genes Chromosomes Cancer 29 4 (2000) 281-291
32. Kalla J., Stilgenbauer S., Schaffner C., et al. Heterogeneity of the API2-MALT1 gene rearrangement in MALT-type lymphoma. Leukemia 14 11 (2000) 1967-1974
33. Lutterbach B., and Hiebert S.W. Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation. Gene 245 2 (2000) 223-235
34. Prokunina L., Castillejo-Lopez C., Oberg F., et al. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat Genet 32 4 (2002) 666-669