Coagulopathy during induced severe intracranial hypertension in a porcine donor model

Anesthesiology

Volumn 110, Issue 6, 2009, Pages 1287-1292

  Barklin, Anne ^a   Tønnesen, Else ^a   Ingerslev, Jørgen ^a   Sørensen, Benny ^b   Fenger Eriksen, Christian ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

THROMBIN; THROMBOPLASTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BALLOON; BLOOD CLOTTING; BLOOD CLOTTING DISORDER; CONTROLLED STUDY; DISEASE MODEL; DISEASE SEVERITY; FEMALE; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; PROTHROMBIN TIME; SWINE; THROMBOELASTOMETRY; TRAUMATIC BRAIN INJURY; ANIMAL; BALLOON DILATATION; BIOSYNTHESIS; BRAIN; DRUG EFFECT; HEMOSTASIS; PATHOLOGY; PHYSIOLOGY; THROMBOELASTOGRAPHY; THROMBOSIS;

ANIMALS; BALLOON DILATATION; BLOOD COAGULATION; BLOOD COAGULATION DISORDERS; BRAIN; FEMALE; HEMOSTASIS; INTRACRANIAL HYPERTENSION; PROTHROMBIN TIME; SWINE; THROMBELASTOGRAPHY; THROMBIN; THROMBOPLASTIN; THROMBOSIS;

EID: 67049100025     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e3181a10352     Document Type: Article

References (31)

1. Vavilala MS, Dunbar PJ, Rivara FP, Lam AM: Coagulopathy predicts poor outcome following head injury in children less than 16 years of age. J Neurosurg Anesthesiol 2001; 13:13-8
2. Pasternak JJ, Hertzfeldt DN, Stanger SR, Walter KR, Werts TD, Marienau ME, Lanier WL: Disseminated intravascular coagulation after craniotomy. J Neurosurg Anesthesiol 2008; 20:15-20
3. Selladurai BM, Vickneswaran M, Duraisamy S, Atan M: Coagulopathy in acute head injury-a study of its role as a prognostic indicator. Br J Neurosurg 1997; 11:398-404
4. MacLeodJB, Lynn M, McKenney MG, Cohn SM, MurthaM: Early coagulopa- thy predicts mortality in trauma. J Trauma 2003; 55:39-44
5. Harhangi BS, Kompanje EJ, Leebeek FW, Maas AI: Coagulation disorders after traumatic brain injury. Acta Neurochir (Wien) 2008; 150:165-75
6. Keimowitz RM, Annis BL: Disseminated intravascular coagulation associated with massive brain injury. J Neurosurg 1973; 39:178-80
7. Rapaport SI, Rao LV: The tissue factor pathway: How it has become a "prima ballerina." Thromb Haemost 1995; 74:7-17
8. Stein SC, Smith DH: Coagulopathy in traumatic brain injury. Neurocrit Care 2004; 1:479-88
9. Brohi K, Cohen MJ, GanterMT, Matthay MA, Mackersie RC, Pittet JF: Acute traumatic coagulopathy: Initiated by hypoperfusion: Modulated through the protein C pathway? Ann Surg 2007; 245:812-8
10. Hess JR, Lawson JH: The coagulopathy of trauma versus disseminated intravascular coagulation. J Trauma 2006; 60:S12-9
11. Fenger-Eriksen C, Anker-Moller E, Heslop J, Ingerslev J, Sorensen B: Thrombelastographic whole blood clot formation after ex vivo addition of plasma substitutes: Improvements of the induced coagulopathy with fibrinogen concentrate. Br J Anaesth 2005; 94:324-9
12. Hemker HC, Wielders S, Kessels H, Beguin S: Continuous registration of thrombin generation in plasma, its use for the determination of the thrombin potential. Thromb Haemost 1993; 70:617-24
13. Sorensen B, Johansen P, Christiansen K, Wöelke M, Ingerslev J: Whole blood coagulation thrombelastographic profiles employing minimal tissue factor activation. J Thromb Haemost 2003; 1:551-8
14. Sorensen B, Ingerslev J: Thromboelastography and recombinant factor VIIa-hemophilia and beyond. Semin Hematol 2004; 41:140-4
15. Sorensen B, IngerslevJ: Tailoring haemostatic treatment to patient requirements-An update on monitoring haemostatic response using thrombelastogra- phy. Haemophilia 2005; 11(Suppl 1):1-6
16. Larsen OH, Ingerslev J, Sorensen B: Whole blood laboratory model of thrombocytopenia for use in evaluation of hemostatic interventions. Ann Hema-tol 2007; 86:217-21
17. Hvitfeldt PL, Christiansen K, Sorensen B, Ingerslev J: Whole blood throm- belastographic coagulation profiles using minimal tissue factor activation can display hypercoagulation in thrombosis-prone patients. Scand J Clin Lab Invest 2006; 66:329-36
18. Papa ML, Capasso F, Pudore L, Torre S, Mango S, Russo V, Delrio P, Palaia R, Ruffolo F, d'Eufemia MD, De Lucia, D Napolitano M, Di Micco P, Parisi V: Thromboelastographic profiles as a tool for thrombotic risk in digestive tract cancer. Exp Oncol 2007; 29:111-5
19. O'Donnell J, Riddell A, Owens D, Handa A, Pasi J, Hamilton G, Perry DJ: Role of the thrombelastograph as an adjunctive test in thrombophilia screening. Blood Coagul Fibrinolysis 2004; 15:207-11
20. Clark JD, Gebhart GF, Gonder JC, Keeling ME, Kohn DF: Special Report:The 1996 Guide forthe Care and Use of Laboratory Animals. ILARJ 1997; 38:41-8
21. Chen EP, Bittner HB, Kendall SW, Van Trigt P: Hormonal and hemody-namic changes in a validated animal model of brain death. Crit Care Med 1996;24:1352-9
22. Roelsgaard K, Botker HE, Stodkilde-Jorgensen H, Andreasen F, Jensen SL, Keiding S: Effects of brain death and glucose infusion on hepatic glycogen and blood hormones in the pig. Hepatology 1996; 24:871-5
23. Pratschke J, Neuhaus P, Tullius SG: What can be learned from brain-death models? Transpl Int 2005; 18:15-21
24. Barklin A, Larsson A, Vestergaard C, Koefoed-Nielsen J, Bach A, Nyboe R, Wogensen L, Tonnesen E: Does brain death induce a pro-inflammatory response at the organ level in a porcine model? Acta Anaesthesiol Scand 2008; 52:621-7
25. Barklin A, Larsson A, Vestergaard C, Kjaergaard A, Wogensen L, Schmitz O, Tonnesen E: Insulin alters cytokine content in two pivotal organs after brain death: A porcine model. Acta Anaesthesiol Scand 2008; 52:628-34
26. Lang T, Bauters A, Braun SL, Potzsch B, von Pape KW, Kolde HJ, LaknerM: Multi-centre investigation on reference ranges for ROTEM thromboelastometry. Blood Coagul Fibrinolysis 2005; 16:301-10
27. Pfenninger J, Plaschkes J, Straume BH: Consumption coagulopathy after severe head injury in children. Z Kinderchir 1982; 37:53-5
28. Hulka F, Mullins RJ, Frank EH: Blunt brain injury activates the coagulation process. Arch Surg 1996; 131:923-7
29. Kozek-Langenecker SA: Effects of hydroxyethyl starch solutions on hemo- stasis. ANESTHESIOIOGY2005; 103:654-60
30. Lwaleed BA, Cooper AJ, Voegeli D, Getliffe K: Tissue factor: A critical role in inflammation and cancer. Biol Res Nurs 2007; 9:97-107
31. Esmon CT: The impact of the inflammatory response on coagulation. Thromb Res 2004; 114:321-7