Endothelialization of heart valve matrix using a computer-assisted pulsatile bioreactor

Tissue Engineering - Part A

Volumn 15, Issue 4, 2009, Pages 807-814

  Lee, Dong Joon ^a,b   Steen, Julie ^a,b   Jordan, James E ^c   Kincaid, Edward H ^c   Kon, Neal D ^c   Atala, Anthony ^a   Berry, Joel ^d   Yoo, James J ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b VA Polytechnic Institute and State University   (United States)

^c WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^d WAKE FOREST UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCONVERSION; BIOMINERALIZATION; BIOREACTORS; BLOOD VESSEL PROSTHESES; CELL MEMBRANES; COAGULATION; COMPUTER CONTROL SYSTEMS; ENDOTHELIAL CELLS; FLOW RATE; HEART VALVE PROSTHESES; INDUSTRIAL CHEMICALS; SCAFFOLDS; SELF ASSEMBLY;

BIOPROSTHETIC HEART VALVES; BIOREACTOR SYSTEM; COAGULATION PROCESS; COMPUTER ASSISTED; DECELLULARIZED; ENDOTHELIAL PROGENITOR CELLS; ENDOTHELIALIZATION; HEART VALVES; IN-VIVO; MATRIX; OPTIMAL FLOWS; STEPWISE INCREASE; VOLUME FLOW RATE;

VALVES (MECHANICAL);

ANIMAL TISSUE; ARTICLE; BIOREACTOR; BIOREACTOR EQUIPMENT; BLOOD CLOTTING; ENDOTHELIUM CELL; FLOW RATE; HEART VALVE; HEART VALVE REPLACEMENT; NONHUMAN; PRIORITY JOURNAL; SHEAR STRESS; SHEEP; STEM CELL; SWINE; THROMBOCYTE ADHESION; ANIMAL; CYTOLOGY; HEART VALVE PROSTHESIS; INSTRUMENTATION; MECHANICAL STRESS; METHODOLOGY; TISSUE ENGINEERING;

SUS;

ANIMALS; BIOREACTORS; ENDOTHELIAL CELLS; HEART VALVE PROSTHESIS; SHEEP; STRESS, MECHANICAL; SWINE; TISSUE ENGINEERING;

EID: 67049097980     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2008.0250     Document Type: Article

References (27)

1. Schoen, F.J., and Levy, R. Tissue heart valve: current challenges and future research perspectives. J Biomed Mater Res 47, 439, 1999.
2. Davis, E.A., Greene, P.S., Cameron, D.E., Gott, V.I., Laschinger, J.C., Stuart, R.S., Sussman, M.S., Watkins, L., and Baumgartner, W.A. Bioprosthetic versus mechanical prostheses for aortic valve replacement in the elderly. Circulation 94(9 Suppl), II121, 1996.
3. Phillips S.J. Searching for the truth: a mechanical or a tissue valve? J Heart Valve Dis 13(Supplement 1), S95, 2004.
4. Rupnick, M.A., Hubbard, F.A., Pratt, K., Jarrell, B.E., and Williams, S.K. Endothelialization of vascular prosthetic surfaces after seeding or sodding with human microvascular endothelial cells. J Vasc Surg 9, 788, 1989.
5. Kaushal, S., Amiel, G.E., Guleserian, K.J., Shapira, O.M., Perry, T., Sutherland, F.W., Rabkin, E., Moran, A.M., Schoen, F.J., Atala, A., Soker, S., Bischoff, J., and Mayer, J.E. Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo. Nat Med 7, 1035, 2001.
6. Cebotari, S., Lichtenberg, A., Tudorache, I., Hilfiker, A., Mertsching, H., Leyh, R., Breymann, T., Kallenbach, K., Maniuc, L., Batrinac, A., Repin, O., Maliga, O., Ciubotaru, A., and Haverich, A. Clinical application of tissue engineered human heart valves using autologous progenitor cells. Circulation 114(1 Suppl), I132, 2006.
7. Barron, V., Lyons, E., Stenson-Cox, C., McHugh, P.E., and Pandit, A. Bioreactors for cardiovascular cell and tissue growth: a review. Ann Biomed Eng 31, 1017, 2003.
8. Engelmayr, G.C., Hildebrand, D.K., Sutherland, F.W., Mayer, J.E., and Sacks, M.S. A novel bioreactor for the dynamic flexural stimulation of tissue engineered heart valve biomaterials. Biomaterials 24, 2523, 2003.
9. Hoerstrup, S.P., Sodian, R., Daebritz, S., Wang, J., Bacha, E.A., Martin, D.P., Moran, A.M., Gulersian, K.J., Sperling, J.S., Sunjay, K., Vacanti, J.P., Schoen, F.J., and Mayer, J.E. Functional living trileaflet heart valves grown in vitro. Circulation 102, 44, 2000.
10. Zeltinger, J., Landeen, L.K., Alexander, H.G., Kidd, I.D., and Sibanda, B. Development and characterization of tissueengineered aortic valves. Tissue Eng 7, 9, 2001.
11. Schenke-Layland, K., Opitz, F., Gross, M., Doring, C., Halbhuber, K.J., Schirrmeister, F., Wahlers, F.T., and Stock, U.A. Complete dynamic repopulation of decellularized heart valves by application of defined physical signals-an in vitrostudy. Cardiovasc Res 60, 497, 2003.
12. Mol, A., Driessen, N.J., Rutten, M.C., Hoerstrup, S.P., Bouten, C.V., and Baaijens, F.P. Tissue engineering of human heart valve leaflets: a novel bioreactor for a strain-based conditioning approach. Ann Biomed Eng 33, 1778, 2005.
13. Lichtenberg,A., Tudorache, I.,Cebotari, S., Ringes-Lichtenberg, S., Sturz, G., Hoeffler, K., Hurscheler, C., Brandes, G., Hilfiker, A., and Haverich, A. In vitro re-endothelialization of detergent decellularized heart valves under simulated physiological dynamic conditions. Biomaterials 27, 4221, 2006.
14. Dumont, K., Yperman, J., Verbeken, E., Segers, P., Meuris, B., Vandenberghe, S., Flameng, W., and Verdonck, P.R. Design of a new pulsatile bioreactor for tissue engineered aortic heart valve formation. Artif Organs 26, 710, 2002.
15. Barron, V., Lyons, E., Stenson-Cox, C., Mchugh, P.E., and Pandit, A. Bioreactors for cardiovascular cell and tissue growth: a review. Ann Biomed Eng 31, 1017, 2003.
16. Dunkern, T.R., Paulitschke, M., Meyer, R., Buttemeyer, R., Hetzer, R., and Burmester, G. A novel perfusion system for the endothelialisation of PTFE grafts under defined flow. Eur J Vasc Endovasc Surg 18, 105, 1999.
17. Hildebrand, D.K., Wu, Z.J., Mayer, J.E., and Sacks, M.S. Design and hydrodynamic evaluation of a novel pulsatile bioreactor for biologically active heart valves. Ann Biomed Eng 32, 1039, 2004.
18. Weston, M.W., LaBorde, D.V., and Yoganathan, A.P. Estimation of the shear stress on the aortic valve leaflet. Ann Biomed Eng 27, 572, 1999.
19. McDonald, P.C., Wilson, J.E., Gao, M., McNeill, S., Spinelli, J.J., Williams, O.D., Harji, S., Kenyon, J., and McManus, B.M. Pentachrome staining: quantitative analysis of human heart valves does anorexigen exposure produce a distinctive morphological lesion? Cardiovasc Pathol 11, 251, 2002.
20. Shadle, P.J., and Barondes, S.H. Adhesion of human platelets to immobilized trimeric collagen. J Cell Biol 95, 361, 1982.
21. Lichtenberg, A., Tudorache, I., Cebotari, S., Suprunov, M., Tudorache, G., Goerler, H., Park, J.K., Hilfiker-Kleiner, D., Ringes-Lichtenberg, S., Karck, M., Brandes, G., Hilfiker, A., and Haverich, A. Preclinical testing of tissue-engineered heart valves re-endothelialized under simulated physiological conditions. Circulation 114(1 Suppl), I559, 2006.
22. Lichtenberg, A., Cebotari, S., Tudorache, I., Sturz, G., Winterhalter, W.F.P., and Hilfiker, A. Flow dependent reendothelialization of tissue engineered heart valves. J Heart Valve Dis 15, 287, 2006.
23. Karamu, N., Golz, K., and Bader, A. The cardiovascular tissue-reactor: a novel device for the engineering of heart valves. Artif Organs 30, 809, 2006.
24. Skowasch, D., Steinmetz, M., Nickenig, G., and Bauriedel, G. Is the degeneration of aortic valve bioprostheses similar to that of native aortic valves? insights into valvular pathology. Expert Rev Med Devices 3, 453, 2006.
25. Leask, R.L., Jain, N., and Butany, J. Endothelium and valvular diseases of the heart. Microsc Res Tech 60, 129, 2003.
26. Butcher, J., and Nerem, R. Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: effects of steady shear stress. Tissue Eng 12, 905, 2006.
27. Leguyader, A., Watanabe, R., Berbe', J., Boumediene, A., Cogne', M., and Laskar, M. Platelet activation after aortic prosthetic valve surgery. Interact Cardiovasc Thorac Surg 5, 60, 2006.