메뉴 건너뛰기




Volumn 11, Issue 5, 2002, Pages 251-262

Quantitative analysis of human heart valves: Does anorexigen exposure produce a distinctive morphological lesion?

Author keywords

Anorexigen exposure; Carcinoid valve disease; Fenfluramine; Floppy valve disease; Heart valve; Phentermine; Quantitative image analysis; Rheumatic valve disease

Indexed keywords

ANOREXIGENIC AGENT; GLYCOSAMINOGLYCAN;

EID: 0036754973     PISSN: 10548807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1054-8807(02)00110-2     Document Type: Article
Times cited : (29)

References (43)
  • 2
    • 0032504948 scopus 로고    scopus 로고
    • The prevalence of cardiac valvular insufficiency assessed by transthoracic echocardiography in obese patients treated with appetite-suppressant drugs
    • Khan M.A., Herzog C.A., St. Peter J.V., Hartley G.G., Madlon-Kay R., Dick C.D., Asinger R.W., Vessey J.T. The prevalence of cardiac valvular insufficiency assessed by transthoracic echocardiography in obese patients treated with appetite-suppressant drugs. N Engl J Med. 339:1998;719-724.
    • (1998) N Engl J Med , vol.339 , pp. 719-724
    • Khan, M.A.1    Herzog, C.A.2    St. Peter, J.V.3    Hartley, G.G.4    Madlon-Kay, R.5    Dick, C.D.6    Asinger, R.W.7    Vessey, J.T.8
  • 3
    • 0032505060 scopus 로고    scopus 로고
    • An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo. Sustained-Release Dexfenfluramine Study Group
    • Weissman N.J., Tighe J.F., Gottdiener J.S., Gwynne J.T. An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo. Sustained-Release Dexfenfluramine Study Group. N Engl J Med. 339:1998;725-732.
    • (1998) N Engl J Med , vol.339 , pp. 725-732
    • Weissman, N.J.1    Tighe, J.F.2    Gottdiener, J.S.3    Gwynne, J.T.4
  • 4
    • 0033213380 scopus 로고    scopus 로고
    • Low prevalence of valvular heart disease in 226 phentermine-fenfluramine protocol subjects prospectively followed for up to 30 months
    • Burger A.J., Sherman H.B., Charlamb M.J., Kim J., Asinas L.A., Flickner S.R., Blackburn G.L. Low prevalence of valvular heart disease in 226 phentermine-fenfluramine protocol subjects prospectively followed for up to 30 months. J Am Coll Cardiol. 34:1999;1153-1158.
    • (1999) J Am Coll Cardiol , vol.34 , pp. 1153-1158
    • Burger, A.J.1    Sherman, H.B.2    Charlamb, M.J.3    Kim, J.4    Asinas, L.A.5    Flickner, S.R.6    Blackburn, G.L.7
  • 5
    • 0032747457 scopus 로고    scopus 로고
    • Echocardiographic prevalence of mitral and/or aortic regurgitation in patients exposed to either fenfluramine-phentermine combination or to dexfenfluramine
    • Kancherla M.K., Salti H.I., Mulderink T.A., Parker M., Bonow R.O., Mehlman D.J. Echocardiographic prevalence of mitral and/or aortic regurgitation in patients exposed to either fenfluramine-phentermine combination or to dexfenfluramine. Am J Cardiol. 84:1999;1335-1338.
    • (1999) Am J Cardiol , vol.84 , pp. 1335-1338
    • Kancherla, M.K.1    Salti, H.I.2    Mulderink, T.A.3    Parker, M.4    Bonow, R.O.5    Mehlman, D.J.6
  • 7
    • 0034063651 scopus 로고    scopus 로고
    • Diet drug-related cardiac valve disease: The Mayo Clinic echocardiographic laboratory experience
    • Teramae C.Y., Connolly H.M., Grogan M., Miller F.A. Diet drug-related cardiac valve disease: the Mayo Clinic echocardiographic laboratory experience. Mayo Clin Proc. 75:2000;456-461.
    • (2000) Mayo Clin Proc , vol.75 , pp. 456-461
    • Teramae, C.Y.1    Connolly, H.M.2    Grogan, M.3    Miller, F.A.4
  • 8
    • 0011223103 scopus 로고    scopus 로고
    • Valvular regurgitation in subjects receiving anti-obesity agents: A consecutive series with follow-up
    • Fisher J.E., Orlandi Q., Ruden R., Price D., Istfan N., Joziatis B.T. Valvular regurgitation in subjects receiving anti-obesity agents: a consecutive series with follow-up. J Am Soc Echocardiogr. 12:1999;370.
    • (1999) J Am Soc Echocardiogr , vol.12 , pp. 370
    • Fisher, J.E.1    Orlandi, Q.2    Ruden, R.3    Price, D.4    Istfan, N.5    Joziatis, B.T.6
  • 10
    • 0034607394 scopus 로고    scopus 로고
    • Valvular abnormalities and cardiovascular status following exposure to dexfenfluramine or phentermine/fenfluramine
    • Gardin J.M., Schumacher D., Constantine G., Davis K.D., Leung C., Reid C.L. Valvular abnormalities and cardiovascular status following exposure to dexfenfluramine or phentermine/fenfluramine. J Am Med Assoc. 283:2000;1703-1709.
    • (2000) J Am Med Assoc , vol.283 , pp. 1703-1709
    • Gardin, J.M.1    Schumacher, D.2    Constantine, G.3    Davis, K.D.4    Leung, C.5    Reid, C.L.6
  • 11
    • 0032404014 scopus 로고    scopus 로고
    • Risk for valvular heart disease among users of fenfluramine and dexfenfluramine who underwent echocardiography before use of medication
    • Wee C.C., Phillips R.S., Aurigemma G., Erban S., Kriegel G., Riley M., Douglas P.S. Risk for valvular heart disease among users of fenfluramine and dexfenfluramine who underwent echocardiography before use of medication. Ann Intern Med. 129:1998;903-905.
    • (1998) Ann Intern Med , vol.129 , pp. 903-905
    • Wee, C.C.1    Phillips, R.S.2    Aurigemma, G.3    Erban, S.4    Kriegel, G.5    Riley, M.6    Douglas, P.S.7
  • 12
    • 0032504983 scopus 로고    scopus 로고
    • A population-based study of appetite-suppressant drugs and the risk of cardiac-valve regurgitation
    • Jick H., Vasilakis C., Weinrauch L.A., Meier C.R., Jick S.S., Derby L.E. A population-based study of appetite-suppressant drugs and the risk of cardiac-valve regurgitation. N Engl J Med. 339:1998;719-724.
    • (1998) N Engl J Med , vol.339 , pp. 719-724
    • Jick, H.1    Vasilakis, C.2    Weinrauch, L.A.3    Meier, C.R.4    Jick, S.S.5    Derby, L.E.6
  • 13
    • 0011201406 scopus 로고    scopus 로고
    • Fifteen year outcome data on patients treated with fenfluramine-phenermine combination
    • Eichelberger J.P., Pearson T.A., Gajary E. Fifteen year outcome data on patients treated with fenfluramine-phenermine combination. J Am Soc Echocardiogr. 12:1999;355.
    • (1999) J Am Soc Echocardiogr , vol.12 , pp. 355
    • Eichelberger, J.P.1    Pearson, T.A.2    Gajary, E.3
  • 14
    • 25944448171 scopus 로고    scopus 로고
    • The natural histology of fenfluramine-associated valvulopathy assessed by echocardiography
    • Mast S., Jollis J., Ryan T., Landolfo C., Crary J. The natural histology of fenfluramine-associated valvulopathy assessed by echocardiography. J Am Coll Cardiol. 35:2000;523A.
    • (2000) J Am Coll Cardiol , vol.35
    • Mast, S.1    Jollis, J.2    Ryan, T.3    Landolfo, C.4    Crary, J.5
  • 15
    • 0011223104 scopus 로고    scopus 로고
    • Regression of multivalvular regurgitation after the cessation of fenfluramine and phentermine treatment
    • Cannistra L.B., Cannistra A.J. Regression of multivalvular regurgitation after the cessation of fenfluramine and phentermine treatment. NeuroReport. 9:1998;2989-2993.
    • (1998) NeuroReport , vol.9 , pp. 2989-2993
    • Cannistra, L.B.1    Cannistra, A.J.2
  • 16
    • 0032738754 scopus 로고    scopus 로고
    • Echocardiographic improvement over time after cessation of use of fenfluramine and phentermine
    • Hensrud D.D., Connolly H.M., Grogan M., Miller F.A., Bailey K.R., Jensen M.D. Echocardiographic improvement over time after cessation of use of fenfluramine and phentermine. Mayo Clin Proc. 74:1999;1191-1197.
    • (1999) Mayo Clin Proc , vol.74 , pp. 1191-1197
    • Hensrud, D.D.1    Connolly, H.M.2    Grogan, M.3    Miller, F.A.4    Bailey, K.R.5    Jensen, M.D.6
  • 17
    • 0002049845 scopus 로고    scopus 로고
    • Regression of heart-valve abnormalities after discontinuation of dexfenfluramine treatment
    • Mancini M.C., Leite C.C., Grinberg M., Halpern A. Regression of heart-valve abnormalities after discontinuation of dexfenfluramine treatment. Int J Obes Relat Metab Disord. 23:1999;S178.
    • (1999) Int J Obes Relat Metab Disord , vol.23
    • Mancini, M.C.1    Leite, C.C.2    Grinberg, M.3    Halpern, A.4
  • 18
    • 0033162130 scopus 로고    scopus 로고
    • Serial echocardiographic and clinical evaluation of valvular regurgitation before, during, and after treatment with fenfluramine or dexfenfluramine and mazindol or phentermine
    • Ryan D.H., Bray G.A., Helmcke F., Sander G., Volaufova J., Greenway F., Subramaniam P., Glancy D.L. Serial echocardiographic and clinical evaluation of valvular regurgitation before, during, and after treatment with fenfluramine or dexfenfluramine and mazindol or phentermine. Obes Res. 7:1999;313-322.
    • (1999) Obes Res , vol.7 , pp. 313-322
    • Ryan, D.H.1    Bray, G.A.2    Helmcke, F.3    Sander, G.4    Volaufova, J.5    Greenway, F.6    Subramaniam, P.7    Glancy, D.L.8
  • 19
    • 0033454750 scopus 로고    scopus 로고
    • Prevalence of valvular-regurgitation associated with dexfenfluramine three to five months after discontinuation of treatment
    • Weissman N.J., Tighe J.F., Gottdiener J.S., Gwynne J.T. Prevalence of valvular-regurgitation associated with dexfenfluramine three to five months after discontinuation of treatment. J Am Coll Cardiol. 34:1999;2088-2095.
    • (1999) J Am Coll Cardiol , vol.34 , pp. 2088-2095
    • Weissman, N.J.1    Tighe, J.F.2    Gottdiener, J.S.3    Gwynne, J.T.4
  • 21
    • 0035916278 scopus 로고    scopus 로고
    • The progression of fenfluramine-associated valvular heart disease assessed by echocardiography
    • Mast S.T., Jollis J.G., Ryan T., Anstrom K.J., Crary J.L. The progression of fenfluramine-associated valvular heart disease assessed by echocardiography. Ann Intern Med. 134:2001;261-266.
    • (2001) Ann Intern Med , vol.134 , pp. 261-266
    • Mast, S.T.1    Jollis, J.G.2    Ryan, T.3    Anstrom, K.J.4    Crary, J.L.5
  • 23
    • 0034595380 scopus 로고    scopus 로고
    • Fenfluramine and phentermine and cardiovascular findings: Effect of treatment duration on prevalence of valve abnormalities
    • Jollis J.G., Landolfo C.K., Kisslo J., Constantine G.D., Davis K.D., Ryan T. Fenfluramine and phentermine and cardiovascular findings: effect of treatment duration on prevalence of valve abnormalities. Circulation. 101:2000;2071-2077.
    • (2000) Circulation , vol.101 , pp. 2071-2077
    • Jollis, J.G.1    Landolfo, C.K.2    Kisslo, J.3    Constantine, G.D.4    Davis, K.D.5    Ryan, T.6
  • 24
    • 0032758778 scopus 로고    scopus 로고
    • The fen-phen controversy: Is regression another piece of the puzzle?
    • Asinger R.W. The fen-phen controversy: is regression another piece of the puzzle? Mayo Clin Proc. 74:1999;1302-1304.
    • (1999) Mayo Clin Proc , vol.74 , pp. 1302-1304
    • Asinger, R.W.1
  • 25
    • 0032923959 scopus 로고    scopus 로고
    • Virus-like particles in the mitral and tricuspid valves explanted from a patient treated with fenfluramine-phentermine
    • Garon C.F., Oury J.H., Duran C.M. Virus-like particles in the mitral and tricuspid valves explanted from a patient treated with fenfluramine-phentermine. J Heart Valve Dis. 8:1999;232.
    • (1999) J Heart Valve Dis , vol.8 , pp. 232
    • Garon, C.F.1    Oury, J.H.2    Duran, C.M.3
  • 26
    • 0032828620 scopus 로고    scopus 로고
    • Histologic changes in three explanted native cardiac valves following use of fenfluramines
    • Steffee C.H., Singh H.K., Chitwood W.R. Histologic changes in three explanted native cardiac valves following use of fenfluramines. Cardiovasc Pathol. 8:1999;245-253.
    • (1999) Cardiovasc Pathol , vol.8 , pp. 245-253
    • Steffee, C.H.1    Singh, H.K.2    Chitwood, W.R.3
  • 27
    • 18844471683 scopus 로고    scopus 로고
    • Endocardial fibrosis associated with fenfluramine-phentermine
    • Fowles R.E., Cloward T.V., Yowell R.L. Endocardial fibrosis associated with fenfluramine-phentermine. N Engl J Med. 338:1998;1316.
    • (1998) N Engl J Med , vol.338 , pp. 1316
    • Fowles, R.E.1    Cloward, T.V.2    Yowell, R.L.3
  • 28
    • 0035218345 scopus 로고    scopus 로고
    • Aortic and mitral fenfluramine-phentermine valvulopathy in 64 patients treated with anorectic agents
    • Volmar K.E., Hutchins G.M. Aortic and mitral fenfluramine-phentermine valvulopathy in 64 patients treated with anorectic agents. Arch Pathol Lab Med. 125:2001;1555-1561.
    • (2001) Arch Pathol Lab Med , vol.125 , pp. 1555-1561
    • Volmar, K.E.1    Hutchins, G.M.2
  • 29
    • 0036020638 scopus 로고    scopus 로고
    • The challenge of defining normality of human mitral and aortic valves: Geometrical and compositional analysis
    • McDonald P.C., Wilson J.E., Gao M., Spinelli J.J., Wiebe H., McNeill S., McManus B.M. The challenge of defining normality of human mitral and aortic valves: geometrical and compositional analysis. Cardiovasc Pathol. 11(4):2002;193-209.
    • (2002) Cardiovasc Pathol , vol.11 , Issue.4 , pp. 193-209
    • McDonald, P.C.1    Wilson, J.E.2    Gao, M.3    Spinelli, J.J.4    Wiebe, H.5    McNeill, S.6    McManus, B.M.7
  • 30
    • 0030454525 scopus 로고    scopus 로고
    • Prominence of apolipoproteins B, (a), and E in the intimae of coronary arteries in transplanted human hearts: Geographic relationship to vessel wall proteoglycans
    • Lin H., Ignatescu M., Wilson J.E., Roberts C.R., Horley K.J., Winters G.L., Costanzo M.R., McManus B.M. Prominence of apolipoproteins B, (a), and E in the intimae of coronary arteries in transplanted human hearts: geographic relationship to vessel wall proteoglycans. J Heart Lung Transplant. 15:1996;1223-1232.
    • (1996) J Heart Lung Transplant , vol.15 , pp. 1223-1232
    • Lin, H.1    Ignatescu, M.2    Wilson, J.E.3    Roberts, C.R.4    Horley, K.J.5    Winters, G.L.6    Costanzo, M.R.7    McManus, B.M.8
  • 31
    • 0030469303 scopus 로고    scopus 로고
    • Biglycan, decorin, and versican protein expression patterns in coronary arteriopathy of human cardiac allograft: Distinctness as compared to native atherosclerosis
    • Lin H., Wilson J.E., Roberts C.R., Horley K.J., Winters G.L., Costanzo M.R., McManus B.M. Biglycan, decorin, and versican protein expression patterns in coronary arteriopathy of human cardiac allograft: distinctness as compared to native atherosclerosis. J Heart Lung Transplant. 15:1996;1233-1247.
    • (1996) J Heart Lung Transplant , vol.15 , pp. 1233-1247
    • Lin, H.1    Wilson, J.E.2    Roberts, C.R.3    Horley, K.J.4    Winters, G.L.5    Costanzo, M.R.6    McManus, B.M.7
  • 32
    • 0022397051 scopus 로고
    • Pathology of surgically excised mitral valves. One hundred consecutive cases
    • Hanson T.P., Edwards B.S., Edwards J.E. Pathology of surgically excised mitral valves. One hundred consecutive cases. Arch Pathol Lab Med. 109:1985;823-828.
    • (1985) Arch Pathol Lab Med , vol.109 , pp. 823-828
    • Hanson, T.P.1    Edwards, B.S.2    Edwards, J.E.3
  • 34
    • 0030668049 scopus 로고    scopus 로고
    • Cardiovascular complications of malignant carcinoid disease
    • Anderson A.S., Krauss D., Lang R. Cardiovascular complications of malignant carcinoid disease. Am Heart J. 134:1997;693-702.
    • (1997) Am Heart J , vol.134 , pp. 693-702
    • Anderson, A.S.1    Krauss, D.2    Lang, R.3
  • 35
    • 0030755423 scopus 로고    scopus 로고
    • A unique heart disease associated with a unique cancer: Carcinoid heart disease
    • Roberts W.C. A unique heart disease associated with a unique cancer: carcinoid heart disease. Am J Cardiol. 80:1997;251-256.
    • (1997) Am J Cardiol , vol.80 , pp. 251-256
    • Roberts, W.C.1
  • 36
    • 0000998303 scopus 로고
    • The aging heart: II. The valves
    • McMillan J.B., Lev M. The aging heart: II. The valves. J Gerontol. 19:1964;1-14.
    • (1964) J Gerontol , vol.19 , pp. 1-14
    • McMillan, J.B.1    Lev, M.2
  • 38
    • 0023753449 scopus 로고
    • Age-related changes in aortic and mitral valve thickness: Implications for two-dimensional echocardiography based on an autopsy study of 200 normal human hearts
    • Sahasakul Y., Edwards W.D., Naessens J.M., Tajik A.J. Age-related changes in aortic and mitral valve thickness: implications for two-dimensional echocardiography based on an autopsy study of 200 normal human hearts. Am J Cardiol. 62:1988;424-430.
    • (1988) Am J Cardiol , vol.62 , pp. 424-430
    • Sahasakul, Y.1    Edwards, W.D.2    Naessens, J.M.3    Tajik, A.J.4
  • 39
    • 0015778655 scopus 로고
    • Valvular, subvalvular and supravalvular aortic stenosis: Morphologic features
    • Roberts W.C. Valvular, subvalvular and supravalvular aortic stenosis: morphologic features. Cardiovasc Clin. 5:1973;97-126.
    • (1973) Cardiovasc Clin , vol.5 , pp. 97-126
    • Roberts, W.C.1
  • 40
    • 0029916335 scopus 로고    scopus 로고
    • Etiology of valvular heart disease
    • Rose A.G. Etiology of valvular heart disease. Curr Opin Cardiol. 11:1996;98-113.
    • (1996) Curr Opin Cardiol , vol.11 , pp. 98-113
    • Rose, A.G.1
  • 41
    • 0023793030 scopus 로고
    • The pathology of mitral valve prolapse
    • Virmani R., Atkinson J.B., Forman M.B. The pathology of mitral valve prolapse. Herz. 13:1988;215-226.
    • (1988) Herz , vol.13 , pp. 215-226
    • Virmani, R.1    Atkinson, J.B.2    Forman, M.B.3
  • 42
    • 0033580464 scopus 로고    scopus 로고
    • Medical progress: Carcinoid tumors
    • Kulke M.H., Mayer R.J. Medical progress: carcinoid tumors. N Engl J Med. 340:1999;858-868.
    • (1999) N Engl J Med , vol.340 , pp. 858-868
    • Kulke, M.H.1    Mayer, R.J.2
  • 43
    • 0026078560 scopus 로고
    • Histochemical and immunohistochemical morphology of carcinoid heart disease
    • Lundin L., Funa K., Hansson H.E., Wilander E., Oberg K. Histochemical and immunohistochemical morphology of carcinoid heart disease. Pathol Res Pract. 187:1991;73-77.
    • (1991) Pathol Res Pract , vol.187 , pp. 73-77
    • Lundin, L.1    Funa, K.2    Hansson, H.E.3    Wilander, E.4    Oberg, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.