Oral glucose and parental holding preferable to opioid in pain management in preterm infants

Clinical Journal of Pain

Volumn 25, Issue 2, 2009, Pages 138-145

  Axelin, Anna ^a   Salanterä, Sanna ^a   Kirjavainen, Jarkko ^b   Lehtonen, Liisa ^c  

^a UNIVERSITY OF TURKU   (Finland)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

^c Central Hospital of Central Finland   (Finland)

Author keywords

Facilitated tucking by parents; Pain management; Preterm infant

Indexed keywords

GLUCOSE; OXYCODONE; PLACEBO; NARCOTIC ANALGESIC AGENT;

ANALGESIA; ARTICLE; CHILD PARENT RELATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; FACILITATED TUCKING BY PARENT; GESTATIONAL AGE; HUMAN; INFANT; INTERMETHOD COMPARISON; KANGAROO CARE; PAIN; PAIN ASSESSMENT; PATIENT SAFETY; PREMATURITY; PRIORITY JOURNAL; PROCEDURAL PAIN; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; TRACHEOBRONCHIAL TOILET; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; HEAT; MALE; METHODOLOGY; NEWBORN; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; PROSPECTIVE STUDY; PSYCHOLOGICAL ASPECT; RETROSPECTIVE STUDY; SLEEP; SUCKING;

ADMINISTRATION, ORAL; ANALGESICS, OPIOID; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; GLUCOSE; HOT TEMPERATURE; HUMANS; INFANT; INFANT, NEWBORN; INFANT, PREMATURE; MALE; OXYCODONE; PAIN; PAIN MEASUREMENT; PARENT-CHILD RELATIONS; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; SLEEP; SUCKING BEHAVIOR;

EID: 67049088723     PISSN: 07498047     EISSN: 15365409     Source Type: Journal    
DOI: 10.1097/AJP.0b013e318181ad81     Document Type: Article

References (51)

1. Stevens B, Yamada J, Ohlsson A. Sucrose for analgesia in newborn infants undergoing painful procedures. Cochrane Database Syst Rev. 2004;3:CD001069.
2. Carbajal R, Lenclen R, Gajdos V, et al. Crossover trial of analgesic efficacy of glucose and pacifier in very preterm neonates during subcutaneous injections. Pediatrics. 2002;2:389-393.
3. Okan F, Coban A, Ince Z, et al. Analgesia in preterm newborns: the comparative effects of sucrose and glucose. Eur J Pediatr. 2007;166:1017-1024.
4. Franck LS. Some pain, some gain: reflections on the past two decades of neonatal pain research and treatment. Neonatal Netw. 2002;21:37-41.
5. Cignacco E, Hamers JPH, Stoffel L, et al. The efficacy of nonpharmacological interventions in the management of procedural pain in preterm and term neonates. A systematic literature review. Eur J Pain. 2007;11:139-152.
6. Corbo MG, Mansi G, Stagni A, et al. Nonnutritive sucking during heelstick procedures decreases behavioral distress in the newborn infant. Biol Neonate. 2000;77:162-167.
7. Johnston CC, Stevens B, Pinelli J, et al. Kangaroo care is effective in diminishing pain response in preterm neonates. Arch Pediatr Adolesc. 2003;157:1084-1088.
8. Ludington-Hoe SM, Hosseini R, Torowicz DL. Skin-to-skin contact (kangaroo care) analgesia for preterm infant heel stick. AACN Clin Issues. 2005;16:373-387.
9. Corff KE, Seideman R, Venkataraman PS, et al. Facilitated tucking: a nonpharmacologic comfort measure for pain in preterm neonates. J Obstet Gynecol Neonatal Nurs. 1995;24: 143-147.
10. Ward-Larson C, Horn RA, Gosnell F. The efficacy of facilitated tucking for relieving procedural pain of endotracheal suctioning in very low birthweight infants. MCN Am J Matern Child Nurs. 2004;29:151-156.
11. Axelin A, Salanterä S, Lehtonen L. 'Facilitated tucking by parents' in pain management of preterm infants-a randomized crossover trial. Early Hum Dev. 2006;82:241-247.
12. Frank LS, Cox S, Allen A, et al. Parental concern and distress about infant pain. Arch Dis Child Fetal Neonatal Ed. 2004;89: F71-F75.
13. Anand KJ, Sippell WG, Aynsley-Green A. Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response. Lancet. 1987;10:62-66.
14. Anand KJ, Barton BA, McIntosh N, et al. Analgesia and sedation in preterm neonates who require ventilatory support: results from the NOPAIN trial. Neonatal outcome and prolonged analgesia in neonates. Arch Pediatr Adolesc Med. 1999;153:331-338.
15. Saarenmaa E, Huttunen P, Leppä luoto J, et al. Alfentanil as procedural pain relief in newborn infants. Arch Dis Child. 1996;75:F103-F107.
16. Debillon T, Bureau V, Savagner C, et al; on behalf of the French National Federation of Neonatologists. Pain management in French neonatal intensive care units. Acta Peadiatr. 2002;91:822-826.
17. Simons SHP, van Dijk M, Anand KS, et al. Do we still hurt newborn babies? A prospective study of procedural pain and analgesia in neonates. Arch Pediatr Adolesc Med. 2003;157: 1058-1064.
18. Simons SHP, van Dijk M, van Lingen RA, et al. Routine morphine infusion in preterm newborns who received ventilatory support. JAMA. 2003;290:2419-2427.
19. Carbajal R, Lenclen R, Jugie M, et al. Morphine does not provide adequate analgesia for acute procedural pain among preterm infants. Pediatrics. 2005;115:1494-1500.
20. Anand KJS, Hall RW, Shephard B, et al; for the NEOPAIN Trial Investigators Group. Effects of morphine analgesia in ventilated preterm neonates: primary outcomes from the NEOPAIN randomized trial. Lancet. 2004;363: 1673-1682.
21. Anand KJ, Hall RW. Pharmacological therapy for analgesia and sedation in the newborn. Arch Dis Child Fetal Neonatal Ed. 2006;91:F448-F453.
22. Leslie A, Marlow N. Non-pharmacological pain relief. Semin Fetal Neonatal Med. 2006;11:246-250.
23. Gibbins S, Stevens B, Hodnett E, et al. Efficacy and safety of sucrose for procedural pain relief in preterm and term neonates. Nurs Res. 2002;51:375-382.
24. Huang CM, Tung WS, Kuo LL, et al. Comparison of pain responses in premature infants to heelstick between containment and swaddling. J Nurs Res. 2004;12:31-39.
25. Grunau RE, Holsti L, Peters JW. Long-term consequences of pain in human neonates. Semin Fetal Neonatal Med. 2006;11:268-275.
26. Stevens B, Johnston C, Petryshen P, et al. Premature Infant Pain Profile: development and initial validation. Clin J Pain. 1996;12:13-22.
27. Lawrence J, Alcock D, McGrath P, et al. The development of a tool to assess neonatal pain. Neonatal Netw. 1993;12:59-66.
28. Ballantyre M, Stevens B, McAllister M, et al. Validation of the Premature Infant Pain Profile in the clinical settings. Clin J Pain. 1999;5:297-303.
29. Stevens B, Johnston C, Franck L, et al. The efficacy of developmentally sensitive interventions and sucrose for relieving procedural pain in very low birth weight neonates. Nurs Res. 1999;48:35-43.
30. Johnston CC, Stremler R, Horton L, et al. Effect of repeated doses of sucrose during heel stick procedure in preterm neonates. Biol Neonate. 1999;75:160-166.
31. Gormally S, Barr RG, Wertheim L, et al. Contact and nutrient caregiving effects on newborn infant pain responses. Dev Med Child Neurol. 2001;43:28-38.
32. Gibbins S, Stevens B. The influence of gestational age on the efficacy and short-term safety of sucrose for procedural pain relief. Adv Neonatal Care. 2003;3:241-249.
33. Modrcin-Talbott MA, Harrison LL, Groer MW, et al. The biobehavioral effects of gentle human touch on preterm infants. Nurs Sci Q. 2003;16:60-67.
34. Grenier IR, Bigsby R, Vergara ER, et al. Comparison of motor self-regulatory and stress behaviors of preterm infants across body positions. Am J Occup Ther. 2003;57:289-297.
35. Harrison LL, Williams AK, Berbaum ML, et al. Physiologic and behavioral effects of gentle human touch on preterm infants. Res Nurs Health. 2000;23:435-446.
36. Feldman R, Weller A, Sirota L, et al. Skin-to-skin contact (kangaroo care) promotes self-regulation in premature infants: sleep-wake cyclicity, arousal modulation, and sustained exploration. Dev Psychol. 2002;38:194-207.
37. Hernandez-Reif M, Diego M, Field T. Preterm infants show reduced stress behaviors and activity after 5 days of massage therapy. Infant Behav Dev. 2007;30:557-561.
38. Diego MA, Field T, Hernandez-Reif M, et al. Preterm infant massage elicits consistent increases in vagal activity and gastric motility that are associated with greater weight gain. Acta Paediatr. 2007;96:1588-1591.
39. Hill S, Engle S, Jorgensen J, et al. Effects of facilitated tucking during routine care of infants born preterm. Pediatr Phys Ther. 2005;17:158-163.
40. Lugo RA, Kern SE. The pharmacokinetics of oxycodone. J Pain Palliat Care Pharmacother. 2004;18:17-30.
41. Kokki H, Rasanen I, Reinikainen M, et al. Pharmacokinetics of oxycodone after intravenous, buccal, intramuscular and gastric administration in children. Clin Pharmacokinet. 2004;4: 613-622.
42. Anand KJS, and the International Evidence-Based Group for Neonatal Pain. Consensus statement for the prevention and management of pain in the newborn. Arch Pediatr Adolesc Med. 2001;155:173-180.
43. Moustogiannis AN, Raju TN, Roohey T, et al. Intravenous morphine attenuates pain induced changes in skin blood flow in newborn infants. Neurol Res. 1996;18:440-444.
44. Bellu R, de Waal KA, Zanini R. Opioids for neonates receiving mechanical ventilation. Cochrane Database Syst Rev. 2005;4: CD004212.
45. Nandi R, Fitzgerald M. Opioid analgesia in the newborn. Eur J Pain. 2005;9:105-108.
46. Holsti L, Grunau RE. Initial validation of the Behavioral Indicators of Infant Pain (BIIP). Pain. 2007;132:264-272.
47. Johnston CC, Stevens BJ, Franck LS, et al. Factors explaining lack of response to heel stick in preterm newborns. J Obstet Gynecol Neonatal Nurs. 1999;28:587-594.
48. Grunau RE, Holsti L, Haley DW, et al. Neonatal procedural pain exposure predicts lower cortisol and behavioral reactivity in preterm infants in the NICU. Pain. 2005;113: 293-300.
49. Craig KD, Whitfield MF, Grunau RV, et al. Pain in the preterm neonate: behavioural and physiological indices. Pain. 1993;52:287-299.
50. Stevens B, Yamada J, Beyene J, et al. Consistent management of repeated procedural pain with sucrose in preterm neonates: is it effective and safe for repeated use over time? Clin J Pain. 2005;21:543-548.
51. World Medical Association Declaration of Helsinki. Available at: http://www.wma.net/e/policy/b3.htm. Accessed on: October 31, 2007.