메뉴 건너뛰기




Volumn 5, Issue 1, 2009, Pages 13-17

Nonviral delivery platform for therapeutic RNAi: Pegylated siRNA/cationic liposome complexes for targeting of the proto-oncogene bcl-2

Author keywords

Bcl 2; Cancer; Cationic liposomes; Gene targeting; Gene therapy; Pegylation; RNA interference; RNAi; SiRNA; Small interfering RNA

Indexed keywords

DOCETAXEL; LIPOSOME; NANOPARTICLE; PROTEIN BCL 2; SMALL INTERFERING RNA;

EID: 66949166003     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/14796694.5.1.13     Document Type: Article
Times cited : (8)

References (14)
  • 1
    • 55349125661 scopus 로고    scopus 로고
    • Tumor regression in mice by delivery of Bcl-2 small interfering RNA with pegylated cationic liposomes
    • Sonoke S, Ueda T, Fujiwara K et al.: Tumor regression in mice by delivery of Bcl-2 small interfering RNA with pegylated cationic liposomes. Cancer Res. 68(2), 8843-8845 (2008).
    • (2008) Cancer Res , vol.68 , Issue.2 , pp. 8843-8845
    • Sonoke, S.1    Ueda, T.2    Fujiwara, K.3
  • 2
    • 9344224580 scopus 로고    scopus 로고
    • Antitumor activity of small interfering RNA/cationic liposome complex in mouse models of cancer
    • Yano J, Hirabayashi K, Nakagawa S et al.: Antitumor activity of small interfering RNA/cationic liposome complex in mouse models of cancer. Clin. Cancer Res. 10(22), 7721-7726 (2004).
    • (2004) Clin. Cancer Res , vol.10 , Issue.22 , pp. 7721-7726
    • Yano, J.1    Hirabayashi, K.2    Nakagawa, S.3
  • 3
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391(6669), 806-811 (1998).
    • (1998) Nature , vol.391 , Issue.6669 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 4
    • 34547584514 scopus 로고    scopus 로고
    • Applications of RNA interference: Current state and prospects for siRNA-based. strategies in vivo
    • Aigner A: Applications of RNA interference: current state and prospects for siRNA-based. strategies in vivo. Appl. Microbiol. Biotechnol. 76(1), 9-21 (2007).
    • (2007) Appl. Microbiol. Biotechnol , vol.76 , Issue.1 , pp. 9-21
    • Aigner, A.1
  • 6
    • 15444373116 scopus 로고    scopus 로고
    • RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI) -complexed siRNA in vivo
    • Urban-Klein B, Werth S, Abuharbeid S, Czubayko F, Aigner A: RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI) -complexed siRNA in vivo. Gene Ther. 12(5), 461-466 (2005).
    • (2005) Gene Ther , vol.12 , Issue.5 , pp. 461-466
    • Urban-Klein, B.1    Werth, S.2    Abuharbeid, S.3    Czubayko, F.4    Aigner, A.5
  • 7
    • 3242733298 scopus 로고    scopus 로고
    • Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo
    • Minakuchi Y, Takeshita F, Kosaka N et al.: Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo. Nucleic Acids Res. 32(13), e109 (2004).
    • (2004) Nucleic Acids Res , vol.32 , Issue.13
    • Minakuchi, Y.1    Takeshita, F.2    Kosaka, N.3
  • 8
    • 33748054817 scopus 로고    scopus 로고
    • RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system
    • Howard KA, Rahbek UL, Liu X et al.: RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system. Mol. Ther. 14(4), 476-484 (2006).
    • (2006) Mol. Ther , vol.14 , Issue.4 , pp. 476-484
    • Howard, K.A.1    Rahbek, U.L.2    Liu, X.3
  • 9
    • 33748636431 scopus 로고    scopus 로고
    • Heidel JD: Linear cyclodextrin-containing polymers and their use as delivery agents. Expert Opin. Drug Deliv. 3(5), 641-646 (2006).
    • Heidel JD: Linear cyclodextrin-containing polymers and their use as delivery agents. Expert Opin. Drug Deliv. 3(5), 641-646 (2006).
  • 10
    • 34547866454 scopus 로고    scopus 로고
    • Nonviral in vivo delivery of therapeutic small interfering RNAs
    • Aigner A: Nonviral in vivo delivery of therapeutic small interfering RNAs. Curr. Opin. Mol. Ther. 9(4), 345-352 (2007).
    • (2007) Curr. Opin. Mol. Ther , vol.9 , Issue.4 , pp. 345-352
    • Aigner, A.1
  • 11
    • 11844283922 scopus 로고    scopus 로고
    • Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat
    • Tan PH, Yang LC, Shih HC, Lan KC, Cheng JT: Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat. Gene Ther. 12(1), 59-66 (2005).
    • (2005) Gene Ther , vol.12 , Issue.1 , pp. 59-66
    • Tan, P.H.1    Yang, L.C.2    Shih, H.C.3    Lan, K.C.4    Cheng, J.T.5
  • 12
    • 41649115210 scopus 로고    scopus 로고
    • Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
    • Kleinman ME, Yamada K, Takeda A et al.: Sequence- and target-independent angiogenesis suppression by siRNA via TLR3. Nature 452(7187), 591-571 (2008).
    • (2008) Nature , vol.452 , Issue.7187 , pp. 591-571
    • Kleinman, M.E.1    Yamada, K.2    Takeda, A.3
  • 13
    • 54949095836 scopus 로고    scopus 로고
    • Misinterpreting the therapeutic effects of siRNA caused by immune stimulation
    • Epub ahead of print
    • Robbins M, Judge A, Ambegia E et al.: Misinterpreting the therapeutic effects of siRNA caused by immune stimulation. Hum. Gene Ther. (2008) (Epub ahead of print).
    • (2008) Hum. Gene Ther
    • Robbins, M.1    Judge, A.2    Ambegia, E.3
  • 14
    • 55549114663 scopus 로고    scopus 로고
    • 5′-Triphosphate-siRNA: Turning gene silencing and Rig-I activation against melanoma
    • Poeck H, Besch R, Maihoefer C et al.: 5′-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma. Nat. Med. 14(11), 1256-1263 (2008).
    • (2008) Nat. Med , vol.14 , Issue.11 , pp. 1256-1263
    • Poeck, H.1    Besch, R.2    Maihoefer, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.