Evaluation of RET polymorphisms in a six-generation family with G533C RET mutation: Specific RET variants may modulate age at onset and clinical presentation

Clinical Endocrinology

Volumn 71, Issue 1, 2009, Pages 56-64

  Tamanaha, Rosana ^a,b   Camacho, Cléber P ^b   Pereira, Alexandre C ^c   Da Silva, Adriana M Álvares ^d   MacIel, Rui M B ^a   Cerutti, Janete M ^a,b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b Genetics Division   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d HOSPITAL HELIÓPOLIS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BIOINFORMATICS; CLINICAL FEATURE; FAMILY; FEMALE; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; HAPLOTYPE; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; ONCOGENE RET; ONSET AGE; PHENOTYPIC VARIATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RNA SPLICING; SINGLE NUCLEOTIDE POLYMORPHISM; THYROID MEDULLARY CARCINOMA;

ADULT; AGE OF ONSET; AGED; AGED, 80 AND OVER; CARCINOMA, MEDULLARY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; PEDIGREE; POINT MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS C-RET; THYROID NEOPLASMS;

EID: 66949149437     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2008.03491.x     Document Type: Article

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