Safety and preliminary efficacy data of a novel Casein Kinase 2 (CK2) peptide inhibitor administered intralesionally at four dose levels in patients with cervical malignancies

BMC Cancer

Volumn 9, Issue , 2009, Pages

  Solares, Ana M ^a   Santana, Agueda ^b   Baladrón, Idania ^c   Valenzuela, Carmen ^c   González, Carlos A ^d   Díaz, Alina ^d   Castillo, Dagnelia ^e   Ramos, Thelvia ^c   Gómez, Roberto ^f   Alonso, Daniel F ^g   Herrera, Luis ^h   Sigman, Hugo ^f   Perea, Silvio E ^h   Acevedo, Boris E ^h   López Saura, Pedro ^c  

^a Gyneco obstetric Hospital Clodomira Acosta Ferrales   (Cuba)

^b Gyneco obstetric Hospital 10 de Octubre   (Cuba)

^c Center for Biological Research Cuba   (Cuba)

^d National Center for Toxicology   (Cuba)

^e Gyneco obstetric Hospital Ramón González Coro   (Cuba)

^f ELEA Laboratories   (Argentina)

^g UNIVERSIDAD NACIONAL DE QUILMES   (Argentina)

^h CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASEIN KINASE II; CIGB 300; UNCLASSIFIED DRUG; CIGB-300; CYCLOPEPTIDE; PROTEIN KINASE INHIBITOR;

ABDOMINAL PAIN; ADULT; ARTICLE; BLEEDING; BLOOD CELL COUNT; BLOOD CHEMISTRY; BLOOD CLOTTING PARAMETERS; BREATHING DISORDER; CLINICAL ARTICLE; CLINICAL TRIAL; COLPOSCOPY; DIZZINESS; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG ERUPTION; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG TOLERABILITY; EDEMA; ELECTROCARDIOGRAM; ERYTHEMA; EYE DISEASE; FACE EDEMA; FACE ERYTHEMA; FEMALE; HEART ARRHYTHMIA; HEART PALPITATION; HEMATOMA; HISTOLOGY; HOT FLUSH; HUMAN; HYPERTENSION; HYPOTENSION; INJECTION SITE DISCOLORATION; INJECTION SITE PAIN; MUSCLE CRAMP; NAUSEA; PRURITUS; RECOMMENDED DRUG DOSE; RED EYE; SIDE EFFECT; SKIN ABRASION; SKIN NECROSIS; SKIN TINGLING; TACHYCARDIA; TASTE DISORDER; TINNITUS; TREMOR; ULCER; URETHRAL PAIN; UTERINE CERVIX BIOPSY; UTERINE CERVIX CANCER; UTERINE CERVIX CONIZATION; VAGINAL BURNING SENSATION; VASOVAGAL SYNDROME; VOMITING; ADOLESCENT; AGED; ALPHAPAPILLOMAVIRUS; DRUG ADMINISTRATION; DRUG ADMINISTRATION ROUTE; DRUG ANTAGONISM; DRUG TOXICITY; GENETICS; ISOLATION AND PURIFICATION; MIDDLE AGED; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX TUMOR; VIROLOGY;

ADOLESCENT; ADULT; AGED; ALPHAPAPILLOMAVIRUS; CASEIN KINASE II; CERVICAL INTRAEPITHELIAL NEOPLASIA; DRUG ADMINISTRATION ROUTES; DRUG ADMINISTRATION SCHEDULE; DRUG TOXICITY; FEMALE; HUMANS; MIDDLE AGED; PEPTIDES, CYCLIC; PROTEIN KINASE INHIBITORS; UTERINE CERVICAL NEOPLASMS; YOUNG ADULT;

EID: 66949144069     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-146     Document Type: Article

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