Gene expression profiles of meningiomas are associated with tumor cytogenetics and patient outcome

Brain Pathology

Volumn 19, Issue 3, 2009, Pages 409-420

  Tabernero, Maria Dolores ^a,b   Maillo, Angel ^a   Gil Bellosta, Carlos J ^a   Castrillo, Abel ^a   Sousa, Pablo ^a   Merino, Marta ^a   Orfao, Alberto ^b  

^a HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

^b UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Array; Cytogenetics; Gene expression; Histopathology; Meningioma

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CHROMOSOME ANALYSIS; FEMALE; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MENINGIOMA; TUMOR RECURRENCE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CYTOGENETIC ANALYSIS; DISEASE-FREE SURVIVAL; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KAPLAN-MEIERS ESTIMATE; MALE; MENINGEAL NEOPLASMS; MENINGIOMA; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 66949113588     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2008.00191.x     Document Type: Article

References (53)

1. Arai H, Beppu T, Wada T, Yoshida Y, Kubo Y, Suzuki M, Ogawa A (1998) Pathological analyses of early recurrence and malignant transformation in meningiomas. Brain Tumor Pathol 15 : 37 40.
2. Bostrom J, Meyer-Puttlitz B, Wolter M, Blaschke B, Weber RG, Lichter P et al (2001) Alterations of the tumor suppressor genes CDKN2A (p16(INK4a), p14(ARF), CDKN2B (p15(INK4b), and CDKN2C (p18(INK4c)) in atypical and anaplastic meningiomas. Am J Pathol 159 : 661 669. (Pubitemid 32751096)
3. Breiman L (2001) Random forests. Mach Learn 45 : 5 32. (Pubitemid 32933532)
4. Cuevas IC, Slocum A, Jun P (2005) Meningioma transcript profiles reveal deregulated Notch signaling pathway. Cancer Res 65 : 5070 5075. (Pubitemid 40827315)
5. De Vitis LR, Tedde A, Vitelli F, Ammannati F, Mennonna P, Bigozzi U et al (1996) Screening for mutations in the neurofibromatosis type 2 (NF2) gene in sporadic meningiomas. Hum Genet 97 : 632 637. (Pubitemid 26112032)
6. Espinosa A, Tabernero MD, Maillo A, Sayagues JM, Ciudad J, Merino M et al (2006) The cytogenetic relationship between primary and recurrent meningiomas points to the need for new treatment strategies in cases at high risk of relapse. Clin Cancer Res 12 : 772 780. (Pubitemid 43259857)
7. Fathallah-Shaykh HM, He B, Zhao LJ, Engelhard HH, Cerullo L, Lichtor T et al (2003) Genomic expression discovery predict pathways and oposing function behind phenotypes. J Biol Chem 278 : 23830 23843.
8. Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S et al (2004) Bioconductor, open software development for computational biology and bioinformatics. Genome Biol 5 : R80.
9. Hsu DW, Efird JT, Hedley-Whyte ET (1998) MIB-1 (Ki-67) index and transforming growth factor-alpha (TGF alpha) immunoreactivity are significant prognostic predictors for meningiomas. Neuropathol Appl Neurobiol 24 : 441 452. (Pubitemid 29002275)
10. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, Speed TP (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4 : 249 264.
11. Kalala JP, Caemaert J, De Ridder L (2004) Primary resected meningiomas: relapses and proliferation markers. In Vivo 18 : 411 416. (Pubitemid 39199984)
12. Ketter R, Henn W, Niedermayer I, Steilen-Gimbel H, Konig J, Zang KD, Steudel WI (2001) Predictive value of progression-associated chromosomal aberrations for the prognosis of meningiomas: a retrospective study of 198 cases. J Neurosurg 95 : 601 607. (Pubitemid 33031421)
13. Ketter R, Urbschat S, Henn W, Feiden W, Beerenwinkel N, Lengauer T et al (2007) Application of oncogenetic trees mixtures as a biostatistical model of the clonal cytogenetic evolution of meningiomas. Int J Cancer 121 : 1473 1480. (Pubitemid 47328705)
14. Ketter R, Rahnenführer J, Henn W, Kim YJ, Feiden W, Steudel WI et al (2008) Correspondence of tumor localization with tumor recurrence and cytogenetic progression in meningiomas. Neurosurgery 62 : 61 69. (Pubitemid 351640249)
15. Kleihues P, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC, Cavenee WK (2002) The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol 61 : 215 925.
16. Lamszus K (2004) Meningioma pathology, genetics and biology. J Neuropathol Exp Neurol 63 : 275 286. (Pubitemid 38429025)
17. Lekanne Deprez RH, Riegman PH, Warringa UL, Groen NA, Stefanko SZ, Koper JW et al (1995) Cytogenetic, molecular genetic and pathological analyses in 126 meningiomas. J Neuropathol Exp Neurol 54 : 224 235.
18. Lekanne Deprez RH, Riegman PH, Groen NA, Warringa UL, van Biezen NA, Molijn AC et al (1995) Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma. Oncogene 10 : 1521 1528.
19. Leone PE, Bello MJ, de Campos JM, Vaquero J, Sarasa JL, Pestana A, Rey JA (1999) NF2 gene mutations and allelic status of 1p, 14q and 22q in sporadic meningiomas. Oncogene 18 : 2231 2239. (Pubitemid 29186924)
20. Leone PE, Mendiola M, Alonso J, Paz-y-Mino C, Pestana A (2003) Implications of a RAD54L polymorphism (2290C/T) in human meningiomas as a risk factor and/or a genetic marker. BMC Cancer 3 : 6.
21. Lomas J, Aminoso C, Gonzalez-Gomez P, Alonso EM, Arjona D, Lopez-Marin I et al (2004) Methylation status of TP73 in meningiomas. Cancer Genet Cytogen 148 : 148 151. (Pubitemid 38083345)
22. Lomas J, Bello MJ, Arjona D, Alonso ME, Martinez-Glez V, Lopez-Marin I et al (2005) Genetic and epigenetic alteration of the NF2 gene in sporadic meningiomas. Genes Chromosomes Cancer 42 : 314 319. (Pubitemid 40171195)
23. Lusis EA, Watson MA, Chicoine MR, Lyman M, Roerig P, Reifenberger G et al (2005) Integrative genomic analysis identifies NDRG2 as a candidate tumor suppressor gene frequently inactivated in clinically aggressive meningioma. Cancer Res 65 : 7121 7126. (Pubitemid 41161241)
24. Mahmood A, Caccamo DV, Tomecek FJ, Malik GM (1993) Atypical and malignant meningiomas: a clinicopathological review. Neurosurgery 33 : 955 963. (Pubitemid 23358388)
25. Maillo A, Orfao A, Sayagues JM, Díaz P, Gomez-Moreta JA, Caballero M et al (2003) New classification scheme for the prognostic stratification of meningioma on the basis of chromosome 14 abnormalities, patient age, and tumor histopathology. J Clin Oncol 21 : 3285 3295. (Pubitemid 46606262)
26. Maiuri F, De Caro MB, Esposito F, Cappabianca P, Strazzullo V, Pettinato G, de Divitiis E (2007) Recurrences of meningiomas: predictive value of pathological features and hormonal and growth factors. J Neurooncol 82 : 63 68. (Pubitemid 46252274)
27. Mathiesen T, Lindquist C, Kihlstron L, Karlsson B (1996) Recurrence of cranial base meningiomas. Neurosurgery 39 : 2 9. (Pubitemid 26230452)
28. Mérel P, Hoang-Xuan K, Sanson M, Moreau-Aubry A, Bijlsma EK, Lazaro C et al (1995) Predominant occurrence of somatic mutations of the NF2 gene in meningiomas and schwannomas. Genes Chromosomes Cancer 13 : 211 216.
29. Mihaila D, Jankowski M, Gutierrez JA, Rosenblum ML, Newsham IF, Bogler O et al (2003) Meningiomas: loss of heterozygosity on chromosome 10 and marker-specific correlations with grade, recurrence, and survival. Clin Cancer Res 9 : 4443 4451. (Pubitemid 37248402)
30. Nunes F, Shen Y, Niida Y, Beauchamp R, Stemmer-Rachamimov AO, Ramesh V et al (2005) Inactivation patterns of NF2 and DAL-1/4.1B (EPB41L3) in sporadic meningioma. Cancer Genet Cytogenet 162 : 135 139. (Pubitemid 41423470)
31. Perry A, Gutmann DH, Reifenberger G (2004) Molecular pathogenesis of meningiomas. J Neurooncol 70 : 183 202. (Pubitemid 39545731)
32. Peyrard M, Pan HQ, Kedra D, Fransson I, Swahn S, Hartman K et al (1996) Structure of the promoter and genomic organization of the human beta-adaptin gene (BAM22) from chromosome 22q12. Genomics 36 : 112 117. (Pubitemid 26277764)
33. Peyrard M, Seroussi E, Sandberg-Nordqvist AC, Xie YG, Han FY, Fransson I et al (1999) The human LARGE gene from 22q12.3-q13.1 is a new, distinct member of the glycosyltransferase gene family. Proc Natl Acad Sci USA 96 : 598 603. (Pubitemid 29061254)
34. Pfisterer WK, Coons SW, Aboul-Enein F, Hendricks WP, Scheck AC, Preul MC (2008) Implicating chromosomal aberrations with meningioma growth and recurrence: results from FISH and MIB-I analysis of grades I and II meningioma tissue. J Neurooncol 87 : 43 50.
35. Polte TR, Hanks SK (1995) Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas. Proc Natl Acad Sci USA 92 : 10678 10682.
36. R Development Core Team (2006) R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing : Vienna, Austria.
37. Riemenschneider MJ, Perry A, Reifenberger G (2006) Histological classification and molecular genetics of meningiomas. Lancet Neurol 5 : 1045 1054. (Pubitemid 44709980)
38. Rieske P, Zakrzewska M, Piaskowski S et al (2003) Molecular heterogeneity of meningioma with INI1 mutation. Mol Pathol 56 : 299 301. (Pubitemid 37243923)
39. Ruttledge MH, Sarrazin J, Rangaratnam S, Phelan CM, Twist E, Merel P et al (1994) Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas. Nat Genet 6 : 180 184. (Pubitemid 24188600)
40. Sasaki T, Hankis GR, Helm GA (2003) Comparison of gene expression profiles between frozen original meningiomas and primary cultures of the meningiomas by Gene Chip. Neurosurgery 52 : 892 899. (Pubitemid 36402878)
41. Sayagués JM, Tabernero MD, Maíllo A, Espinosa A, Rasillo A, Díaz P et al (2004) Intratumoral patterns of clonal evolution in meningiomas as defined by multicolor interphase fluorescence in situ hybridization (FISH). Is there a relationship between histopathologically benign and atypical/anaplastic lesions? J Mol Diagn 6 : 316 325. (Pubitemid 39517399)
42. Sayagués JM, Tabernero MD, Maíllo A, Trelles O, Espinosa A, Sarasquete ME et al (2006) Microarray-based analysis of spinal vs intracranial meningiomas: different clinical, biological and genetic characteristics associated with distinct patterns of gene expression. J Neuropathol Exp Neurol 65 : 445 454. (Pubitemid 44297266)
43. Stafford SL, Perry A, Suman VJ, Meyer FB, Scheithauer BW, Lohse CM, Shaw EG (1998) Primarily resected meningiomas: outcome and prognostic factors in 581 Mayo Clinic patients, 1978 through 1988. Mayo Clin Proc 73 : 936 942. (Pubitemid 28467692)
44. Tabernero MD, Espinosa AB, Maillo A, Rebelo O, Fernandez-Vera J, Sayagues JM et al (2007) Patient gender is associated with distinct patterns of chromosomal abnormalities and sex chromosome linked gene expression profiles in Meningiomas. Oncologist 12 : 1225 1236. (Pubitemid 350106353)
45. van Tilborg AA, Al Allak B, Velthuizen SC, de Vries A, Kros JM, Avezaat CJ et al (2005) Chromosomal instability in meningiomas. J Neuropathol Exp Neurol 64 : 312 322. (Pubitemid 40489558)
46. Venables WN, Ripley BD (2002) Modern Applied Statistics with S. Springer : New York, NY.
47. Wada K, Maruno M, Suzuki T, Kagawa N, Hashiba T, Fujimoto Y et al (2005) Chromosomal and genetic abnormalities in benign and malignant meningiomas using DNA microarray. Neurol Res 27 : 747 754. (Pubitemid 41513084)
48. Watson MA, Gutmann DH, Peterson K, Chicoine MR, Kleinschmidt-Demasters BK, Brown HG, Perry A (2002) Molecular characterization of human meningiomas by gene expression profiling using high-density oligonucleotide microarrays. Am J Pathol 161 : 665 671.
49. Weber RG, Bostrom J, Wolter M, Baudis M, Collins VP, Reifenberger G, Lichter P (1997) Analysis of genomic alterations in benign, atypical, and anaplastic meningiomas: toward a genetic model of meningioma progression. Proc Natl Acad Sci USA 94 : 14719 14724. (Pubitemid 28041440)
50. Wellenreuther R, Kraus JA, Lenartz D, Menon AG, Schramm J, Louis DN et al (1995) Analysis of the neurofibromatosis 2 gene reveals molecular variants of meningioma. Am J Pathol 146 : 827 832.
51. Wrobel G, Roerig P, Kokocinski F, Neben K, Hahn M, Reifenberger G, Lichter P (2004) Microarray-based gene expression profiling of benign, atypical and anaplastic meningiomas identifies novel genes associated with meningioma progression. Int J Cancer 114 : 249 256.
52. Yamasaki F, Yoshioka H, Hama S, Sugiyama K, Arita K, Kurisu K (2000) Recurrence of meningiomas. Cancer 89 : 1102 1110.
53. Zattara-Cannoni H, Gambarelli D, Dufour H, Figarella D, Vollot F, Grisoli F, Vagner-Capodano AM (1998) Contribution of cytogenetics and FISH in the diagnosis of meningiomas. A study of 189 tumours. Ann Genet 41 : 164 175. (Pubitemid 28486314)